Results 111 to 120 of about 313,250 (274)

Relationship between age and ventral striatum activation during total win > neutral trials in the MTwiNS sample.

, 2022
k = number of voxels within the cluster. Significant clusters were identified in SPM12 using a mask of the ventral striatum [9], grey matter segmented using AFNI [36].
Laura Murray (658039), Luke W. Hyde (6040277), Kelly L. Klump (7592861), Melissa K. Peckins (12042132), Martha Alves (12042138), Alison L. Miller (6598215), Ashley N. Gearhardt (8530209), Julie C. Lumeng (12042141), Heidi B. Westerman (12042135), S. Alexandra Burt (9457148)   +9 more
core   +1 more source

Tracking Genetic Parkinson's Disease with Molecular Imaging: A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is a worldwide, complex neurodegenerative disorder influenced by both genetic and environmental factors. Around 15–20% of PD cases are linked to genetic mutations, providing insights into the disease's pathogenesis.
Chiara Meneghini, Luca Gallo, Arianna Sala, Enza Maria Valente, Micol Avenali, Silvia Paola Caminiti   +5 more
wiley   +1 more source

Hippocampal projections to the ventral striatum: from spatial memory to motivated behavior

, 2014
Multiple regions of the hippocampal formation project to the ventral striatum, a central node in brain circuits that subserve aspects of motivation. These projections emphasize information flow from the ventral (temporal) pole of the hippocampus and ...
Pennartz, C.M.A.; id_orcid, Lansink, C.S., van der Meer, M.M.A, Ito, R.   +3 more
core   +2 more sources

Depression in Parkinson’s disease is associated with reduced ventral striatal dopamine transporter binding

npj Parkinson's Disease
Major depressive disorder (MDD) is a common non-motor symptom in Parkinson’s disease (PD), affecting one third of patients. Dopaminergic deficits have been hypothesised to contribute to PD-MDD, but direct molecular evidence is limited.
Jessica E. M. C. Dirkx, Filip Grill, Nienke Dijk, Roshan Cools, Jan Booij, Bastiaan R. Bloem, Rick C. G. Helmich, Henricus G. Ruhé, Maria H. C. T. van Beek   +8 more
doaj   +1 more source

The Hypoactivity Associated with the Repeated Exposure to Atrazine Is Related to Decreases in the Specific Binding to D1-DA Receptors in the Striatum of Rats

Journal of Toxicology, 2017
The herbicide atrazine (ATR) has a potential toxic effect on the neuronal circuits of the brain, specifically on two major dopaminergic pathways: the nigrostriatal and mesolimbic circuits.
José Abraham Márquez-Ramos, Isela Hernández-Plata, Mauricio Díaz-Muñoz, Verónica M. Rodríguez   +3 more
doaj   +1 more source

Apathy in Parkinson's Disease: Distinguishing Overlapping Symptoms Via Network Analysis

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Anxiety, fatigue, and excessive daytime sleepiness (EDS) frequently co‐occur in Parkinson's disease (PD) and can influence the clinical determination of apathy. Objective To distinguish patient‐reported apathy from other non‐motor symptoms.
Joseph Seemiller, Abhimanyu Mahajan, Christopher B. Morrow, Joseph F. McGuire, Dawn Bowers, Kelly A. Mills, Gregory M. Pontone   +6 more
wiley   +1 more source

Acute and Chronic Local Field Potential Recordings in Dystonia—A Systematic Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Dystonia is a hyperkinetic movement disorder increasingly conceptualized as a disorder of distributed network dysfunction involving the basal ganglia, cortex and cerebellum. Local field potentials (LFPs) recorded from deep brain stimulation (DBS) electrodes provide a unique opportunity to characterize the electrophysiological signatures ...
Jack Horan, Eoghan Donlon, Aoibheann Gill, Rosalyn Moran, Conor Fearon, Richard A. Walsh, Catherine Moran   +6 more
wiley   +1 more source

Matrix-biased excitatory and inhibitory inputs to the striatum involving external segment of the globus pallidus

Frontiers in Cellular Neuroscience
IntroductionThe external segment of the globus pallidus (GPe) is traditionally viewed as a relay nucleus within the indirect basal ganglia pathway. However, a subpopulation of GPe neurons projects directly to the striatum, raising questions about their ...
Fuyuki Karube, Kenta Kobayashi, Fumino Fujiyama   +2 more
doaj   +1 more source

Continuous Subcutaneous Apomorphine as a Temporary Bridging Therapy for Dopamine Dysregulation Syndrome in Patients with Deep Brain Stimulation

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dopamine dysregulation syndrome (DDS) is a challenging complication of dopaminergic therapy in Parkinson's disease and can persist despite subthalamic deep brain stimulation (STN‐DBS). We evaluated a temporary bridging concept in which oral dopaminergic medication was replaced by continuous subcutaneous apomorphine infusion while ...
Tobias Binder, Johannes Hartig, Lennart Sitzmann, Chi Wang Ip, Philipp Capetian, Florian Lange, Martin Reich, Christine Daniels, Jens Volkmann   +8 more
wiley   +1 more source

Apathy in Lewy Body Disorders: A Position Paper

Movement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky, Lidia Bojtos, Milica G. Kramberger, Elisa Mantovani, Iulia Murasan, Jose‐Alberto Palma, Karolina Poplawska‐Domaszewicz, Anna Sauerbier, Kallol Ray Chaudhuri, Per Odin, Daniel Weintraub, Anette Schrag, Cristian Falup‐Pecorariu   +12 more
wiley   +1 more source