Results 151 to 160 of about 313,250 (274)

Ventral striatum dopamine release encodes unique properties of visual stimuli in mice. [PDF]

open access: yesElife, 2023
Gonzalez LS   +5 more
europepmc   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

open access: yesObesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey   +7 more
wiley   +1 more source

Nature, nurture, and 5‐HT4R: Familial predisposition, not parental bonding, is associated with brain 5‐HT4R in a sex‐specific manner

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Background Major depressive disorder (MDD) aggregates in families. The neostriatum, key to reward and attachment circuits, has the highest density of serotonin 4 receptors (5‐HT4R). Striatal 5‐HT4R is low in MDD and linked to familial depression risk. Poor parental bonding increases depression risk, yet whether nature and nurture converge on 5‐HT4R is ...
Randi T. Kjær   +2 more
wiley   +1 more source

Parkinson's disease under dopamine replacement therapy as a human framework for studying addiction‐relevant mechanisms

open access: yesPsychiatry and Clinical Neurosciences, EarlyView.
Addiction is a chronic relapsing condition characterized by compulsive reward seeking and impaired behavioral control, associated with major individual and societal burden. Mechanistic investigation in humans remains constrained by ethical limitations, uncontrolled exposure histories, and ecological confounds.
Vanessa Fleury   +6 more
wiley   +1 more source

Finding the Words: How Does the Aging Brain Process Language? A Focused Review of Brain Connectivity and Compensatory Pathways

open access: yesTopics in Cognitive Science, EarlyView.
Abstract As people age, there is a natural decline in cognitive functioning and brain structure. However, the relationship between brain function and cognition in older adults is neither straightforward nor uniform. Instead, it is complex, influenced by multiple factors, and can vary considerably from one person to another.
Monica Baciu, Elise Roger
wiley   +1 more source

Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications

open access: yesExperimental Physiology, EarlyView.
Abstract Placebo and nocebo effects on pain provide a model for investigating how cognitive and contextual factors modulate the physiological processes underlying nociception and its regulation. However, existing accounts remain fragmented and lack a unifying mechanistic framework linking brain, behaviour and autonomic responses.
Denisa Adina Zamfira   +4 more
wiley   +1 more source

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