Results 1 to 10 of about 76,436 (232)
Verapamil and the myocardium [PDF]
Postgraduate Medical Journal, 1974 SummaryAlthough many of the drugs which recently have been developed for use in relieving angina pectoris display β-adrenoceptor blocking activity this property cannot be essential, because verapamil relieves angina pectoris without blocking the cardiac β-adrenoceptors.
Winifred G. Nayler, Dennis M. Krikler
openaire +3 more sources
Mechanism Underlying the Reversal of Drug Resistance in P-Glycoprotein-Expressing Leukemia Cells by Pinoresinol and the Study of a Derivative [PDF]
, 2017 P-glycoprotein (P-gp) is a membrane protein associated with multidrug resistance (MDR) due to its key role in mediating the traffic of chemotherapeutic drugs outside cancer cells, leading to a cellular response that hinders efforts toward successful ...
Carpinella, Maria Cecilia +10 more
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Light sheet microscopy with acoustic sample confinement [PDF]
, 2019 Contactless sample confinement would enable a whole host of new studies in developmental biology and neuroscience, in particular, when combined with long-term, wide-field optical imaging.
Cochran, Sandy +9 more
core +7 more sources
Comprehensive translational assessment of human-induced pluripotent stem cell derived cardiomyocytes for evaluating drug-induced arrhythmias [PDF]
, 2016 Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CM) hold promise for assessment of drug-induced arrhythmias and are being considered for use under the comprehensive in vitro proarrhythmia assay (CiPA).
Blinova, Ksenia +17 more
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Cluster headache management and beyond [PDF]
, 2015 The therapeutic management of cluster headache is based on a very stable triad of drugs. Acute treatment has, in subcutaneous sumatriptan, its gold standard if compared to pure oxygen or indomethacin.
Martelletti, Paolo
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Verapamil in arrhythmia. [PDF]
British Journal of Clinical Pharmacology, 1986 The antiarrhythmic effects of verapamil were observed before it was appreciated that it was a calcium ion‐antagonist. Intravenous verapamil is highly effective in the termination of paroxysmal reciprocating atrioventricular tachycardia, whether associated with preexcitation or involving the atrioventricular node alone.
openaire +3 more sources
Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats [PDF]
, 2019 From studies on different species and in cell culture systems, it has been suggested that vitamin D metabolites might affect themetabolism and elimination of xenobiotics.
Hansen, Kathrin +7 more
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Identification of side population cells in mouse primordial germ cells and prenatal testis [PDF]
, 2011 In mammals, the stem cells of spermatogenesis are derived from an embryonic cell population called primordial germ cells (PGCs). Spermatogonial stem cells displaying the "side population" (SP) phenotype have been identified in the immature and adult ...
De Felici, Massimo +6 more
core +2 more sources