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COMPARISON OF APOPTOSIS IN CONTRALATERAL RENAL TUBULAR CELLS IN ORYCTALAGUS CUNICULUS DUE TO ARTIFICIAL UNILATERAL URETERAL OBSTRUCTION, WITH AND WITHOUT VERAPAMIL [PDF]

open access: yesJurnal Urologi Indonesia, 2016
Objective: To compare the effects of verapamil on the contralateral kidney affected by unilateral ureter obstruction. Material & method: The right ureter of oryctalagus cuniculus rabbits, were obstructed surgically with silk suture material, and kept ...
Djoyo M Boetoro   +4 more
doaj   +3 more sources

Comparative Effects of Verapamil, Nicardipine, and Nitroglycerin on Myocardial Ischemia/Reperfusion Injury [PDF]

open access: yesAnesthesiology Research and Practice, 2011
The aim of this experiment was to establish whether verapamil, nicardipine, and nitroglycerin have (1) infarct size-limiting effects and (2) antiarrhythmic effects in in vivo rabbit hearts during ischemia/reperfusion.
Hitoshi Yui   +6 more
doaj   +4 more sources

PROTECTIVE EFFECTS OF VERAPAMIL AGAINST HEXACHLOROBUTADIENE NEPHROTOXICITY IN RATS [PDF]

open access: yesPakistan Veterinary Journal, 2008
In order to evaluate the protective effect of verapamil against hexachlorobutadiene (HCBD) nephrotoxicity, 30 adult Wistar albino rats were divided into five equal groups, A, B, C, D and E and were given intra-peritonially corn oil (I ml/kg; control ...
E. MOGHTADAI KHORASGANI, K. MANOCHEHRI AND M. HOSSEINI1
doaj   +2 more sources

Evaluating the antidiabetic effects of R-verapamil in type 1 and type 2 diabetes mellitus mouse models.

open access: yesPLoS ONE, 2021
The global incidence of diabetes mellitus (DM) is increasing. Types 1 and 2 DM are associated with declining β-cell function. Verapamil (50% S-verapamil and 50% R-verapamil) can treat DM by downregulating thioredoxin-interacting protein (TXNIP), which ...
Yu-Syuan Chen   +8 more
doaj   +2 more sources

An in silico drug repurposing pipeline to identify drugs with the potential to inhibit SARS-CoV-2 replication [PDF]

open access: yesInformatics in Medicine Unlocked (2023): 101387, 2021
Drug repurposing provides an opportunity to redeploy drugs, which ideally are already approved for use in humans, for the treatment of other diseases. For example, the repurposing of dexamethasone and baricitinib has played a crucial role in saving patient lives during the ongoing SARS-CoV-2 pandemic.
arxiv   +1 more source

Solanaceae glycoalkaloids: α-solanine and α-chaconine modify the cardioinhibitory activity of verapamil

open access: yesPharmaceutical Biology, 2022
Context Solanaceae glycoalkaloids (SGAs) possess cardiomodulatory activity.Objective This study investigated the potential interaction between verapamil and glycoalkaloids.Material and methods The cardioactivity of verapamil and glycoalkaloids (α ...
Szymon Chowański   +9 more
doaj   +1 more source

Effects of Verapamil on the Reduction of Radial Artery Thrombosis after Coronary Angiography: A Randomized Clinical Trial

open access: yesJournal of Tehran University Heart Center, 2022
Background: The trans-radial approach significantly reduces access bleeding and underlying vascular complications and is associated with lower healthcare costs than the transfemoral approach.
Mohammadreza Beyranvand   +3 more
doaj   +1 more source

Verapamil and the myocardium [PDF]

open access: yesPostgraduate Medical Journal, 1974
SummaryAlthough many of the drugs which recently have been developed for use in relieving angina pectoris display β-adrenoceptor blocking activity this property cannot be essential, because verapamil relieves angina pectoris without blocking the cardiac β-adrenoceptors.
Winifred G. Nayler, Dennis M. Krikler
openaire   +3 more sources

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