Results 111 to 120 of about 46,600 (231)

Effects of verapamil and diltiazem on human platelet function

open access: yes, 1986
In this study the antiplatelet properties of two calcium channel blockers, verapamil and diltiazem, were evaluated. In 20 random aspirin-abstaining donors, both diltiazem and verapamil (0.01-10 microM) reduced epinephrine-induced aggregation [46 +/- 6% (
C. A. Fisher   +5 more
core   +1 more source

Ruxolitinib Pharmacokinetics and Exposure–Toxicity Relationship in Hematologic Malignancies and Immune‐Mediated Diseases: A Prospective Observational Study

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 753-761, September 2026.
Ruxolitinib pharmacokinetics (PK) has been characterized in clinical trials but remains poorly documented in real‐world practice. This project aimed to investigate ruxolitinib PK in routine clinical practice, identify factors driving its variability, and explore exposure–response relationships to assess the potential role of therapeutic drug monitoring.
Jérémie Tachet   +11 more
wiley   +1 more source

Verapamil, another CCB, had no effect the tumor growth invivo.

open access: yes, 2014
a) Verapamil had no obvious effect on tumor size in nude mice injected with 5⋅106 MDA-MB-231-GFP cells. Results represented the mean ± SEM. n = 10; P>0.05, Mixed Model in SAS software. b) Effect of different periods with verapamil on the tumor weight. No
Yu-Chun Gu (667398)   +3 more
core   +1 more source

CORDARONE AND VERAPAMIL EFFECTIVENESS IN PRE-HOSPITAL TREATMENT OF ATRIAL FIBRILLATION PAROXYSMS

open access: yesРоссийский кардиологический журнал, 2009
In 263 patients with atrial fibrillation lasting for 0,5–30 hours, pre-hospital antiarrythmic therapy (cordarone 5 mg/kg, verapamil 5–10 mg) was ineffective in the first hour.
V. G. Epifanov   +3 more
doaj  

Neurocardiology: Brain–Heart Interactions in the Heart

open access: yesMedComm, Volume 7, Issue 9, September 2026.
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang   +3 more
wiley   +1 more source

HEMODYNAMIC CONTROL AFTER TRACHEAL INTUBATION: LIDOCAINE VS VERAPAMIL

open access: yesJournal of Research in Medical Sciences, 2001
Introduction. Laryngoscopy and tracheal intubation cause sympathetic and parasympathetic stimulation that in turn, result in dangerous cardiovascular signs like elevation of systolic and diastolic blood pressure and heart rate.
M RAFIEI, J HASHEMI, P KASHEFI
doaj  

Prognostic Value of Spatial Trajectory of J‐Point Amplitude Across Left Precordial Leads in a Community‐Based Population

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 5, September 2026.
In NHANES III adults, latent class trajectory analysis identified a J‐point phenotype characterized by higher V4 amplitude and a steep decline toward V6. This spatial trajectory was independently associated with increased long‐term all‐cause mortality and cardiac death, suggesting prognostic value beyond conventional early repolarization criteria ...
Chenhui Tai, Zhe Wang
wiley   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, Volume 104, Issue 6, Page e630-e647, September 2026.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Tear Fluid Calcitonin Gene‐Related Peptide Levels Are Elevated in Glycerol Trinitrate‐Induced Cluster Headache Attacks: Results From an Exploratory Study

open access: yesEuropean Journal of Neurology, Volume 33, Issue 9, September 2026.
Cluster headache (CH) is a severe primary headache disorder and the neuropeptide calcitonin gene‐related peptide (CGRP) has been shown to be elevated ictally and interictally. We investigated tear fluid CGRP levels during experimental cluster headache attacks and showed elevated CGRP levels during these headache attacks.
Katharina Kamm   +4 more
wiley   +1 more source

Chronopharmacology of verapamil in Stage I-II arterial hypertension

open access: yesКардиоваскулярная терапия и профилактика, 2009
Aim. To compare the pharmacokinetics and pharmacodynamics of verapamil retard, regularly taken by patients  with Stage I-II arterial hypertension (AH). Material and methods. The effects of the administration time (morning vs. evening) on verapamil retard
V. G. Belolipetskaya   +8 more
doaj  

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