Results 111 to 120 of about 46,600 (231)
Effects of verapamil and diltiazem on human platelet function
In this study the antiplatelet properties of two calcium channel blockers, verapamil and diltiazem, were evaluated. In 20 random aspirin-abstaining donors, both diltiazem and verapamil (0.01-10 microM) reduced epinephrine-induced aggregation [46 +/- 6% (
C. A. Fisher +5 more
core +1 more source
Ruxolitinib pharmacokinetics (PK) has been characterized in clinical trials but remains poorly documented in real‐world practice. This project aimed to investigate ruxolitinib PK in routine clinical practice, identify factors driving its variability, and explore exposure–response relationships to assess the potential role of therapeutic drug monitoring.
Jérémie Tachet +11 more
wiley +1 more source
Verapamil, another CCB, had no effect the tumor growth invivo.
a) Verapamil had no obvious effect on tumor size in nude mice injected with 5⋅106 MDA-MB-231-GFP cells. Results represented the mean ± SEM. n = 10; P>0.05, Mixed Model in SAS software. b) Effect of different periods with verapamil on the tumor weight. No
Yu-Chun Gu (667398) +3 more
core +1 more source
CORDARONE AND VERAPAMIL EFFECTIVENESS IN PRE-HOSPITAL TREATMENT OF ATRIAL FIBRILLATION PAROXYSMS
In 263 patients with atrial fibrillation lasting for 0,5–30 hours, pre-hospital antiarrythmic therapy (cordarone 5 mg/kg, verapamil 5–10 mg) was ineffective in the first hour.
V. G. Epifanov +3 more
doaj
Neurocardiology: Brain–Heart Interactions in the Heart
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang +3 more
wiley +1 more source
HEMODYNAMIC CONTROL AFTER TRACHEAL INTUBATION: LIDOCAINE VS VERAPAMIL
Introduction. Laryngoscopy and tracheal intubation cause sympathetic and parasympathetic stimulation that in turn, result in dangerous cardiovascular signs like elevation of systolic and diastolic blood pressure and heart rate.
M RAFIEI, J HASHEMI, P KASHEFI
doaj
In NHANES III adults, latent class trajectory analysis identified a J‐point phenotype characterized by higher V4 amplitude and a steep decline toward V6. This spatial trajectory was independently associated with increased long‐term all‐cause mortality and cardiac death, suggesting prognostic value beyond conventional early repolarization criteria ...
Chenhui Tai, Zhe Wang
wiley +1 more source
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Cluster headache (CH) is a severe primary headache disorder and the neuropeptide calcitonin gene‐related peptide (CGRP) has been shown to be elevated ictally and interictally. We investigated tear fluid CGRP levels during experimental cluster headache attacks and showed elevated CGRP levels during these headache attacks.
Katharina Kamm +4 more
wiley +1 more source
Chronopharmacology of verapamil in Stage I-II arterial hypertension
Aim. To compare the pharmacokinetics and pharmacodynamics of verapamil retard, regularly taken by patients with Stage I-II arterial hypertension (AH). Material and methods. The effects of the administration time (morning vs. evening) on verapamil retard
V. G. Belolipetskaya +8 more
doaj

