Results 91 to 100 of about 46,600 (231)

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier, Anna S. Savchenko, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Increased quinidine plasma concentrations during administration of verapamil: A new quinidine-verapamil interaction

, 1986
A number of drug interactions that involve quinidine have been reported. 1 These include both pharmacokinetic interactions in which plasma concentrations of other drugs, most notably digoxin, are influenced by quinidine, and pharmacologic interactions ...
Estes, Daneil M, Kessler, Kenneth M, Castellanos, Agustin, Palomo, Andres R, Trohman, Richard G, Myerburg, Robert J   +5 more
core   +1 more source

A prospective, randomized, single - blind study comparing intraplaque injection of thiocolchicine and verapamil in Peyronie's Disease: a pilot study

International Brazilian Journal of Urology
Objectives: To compare the response to tiocolchicine and verapamil injection in the plaque of patients with Peyronie's disease. Materials and Methods: Prospective, single-blind, randomized study, selecting patients who have presented Peyronie's disease ...
I. L. Toscano Jr., M.V. Rezende, L. F. Mello, L. Pires, D. Paulillo, S. Glina   +5 more
doaj   +1 more source

STAT3 and Nrf2 pathways modulate the protective effect of verapamil on lung injury of diabetic rats

Endocrine Regulations, 2018
Objective. We aimed to assess the protective role of verapamil, L-type calcium channel blockers, against early lung damage in diabetic rats. Lung injury has recently been recognized as a consequent complication of diabetes mellitus. Hyperglycemia induces
Mohamed Mervat Z., Hafez Heba M., Mohamed Hanaa H., Zenhom Nagwa M.   +3 more
doaj   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, Volume 101, Issue 10, Page 2571-2580, October 2026.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source

Immediate effect of verapamil on pulmonary functions in bronchial asthma

, 1987
This article describes the immediate effect of verapamil, a calcium antagonist, on pulmonary functions in bronchial asthma. The effect of oral administration of 80 mg of verapamil or placebo was studied in a randomized double-blind manner in 30 extrinsic
Sharma, S. K., Sailo, J. L., Guleria, J. S.   +2 more
core   +1 more source

Suppression of Gelatinase Activity in Human Peripheral Blood Mononuclear Cells by Verapamil [PDF]

Cell Journal, 2014
Objective: Gelatinases are a large group of proteolytic enzymes that belong to the matrix metalloproteinases (MMPs). MMPs are a broad family of peptidases, which proteolyse the extracellular matrix and have an important role in inflammation. Verapamil is
Fatemeh Hajighasemi, Neda Kakadezfuli
doaj  

Updated Estimates of Agreement Between Dispensed Medications and Forensic Toxicology in Sweden

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose To present updated estimates from a nationwide Swedish study comparing dispensed medications with forensic toxicological findings (2006–2013), following re‐evaluation of the toxicology dataset to address periods with non‐uniform analytical detection and inconsistent testing.
Heidi Taipale, Jari Tiihonen, Antti Tanskanen, Jonas Forsman   +3 more
wiley   +1 more source

Recent Updates in Surgical and Non‐Surgical Management of Peyronie's Disease: Implications for Modern Clinical Practice

Trends in Urology &Men's Health, Volume 17, Issue 5, October 2026.
ABSTRACT The management of Peyronie's Disease (PD) remains a clinical challenge to urologists due to its dynamic and heterogeneous nature, variable psychosocial burden, with wide‐ranging treatments, both non‐surgical and surgical. Recent advances in Peyronie's disease (PD) include refined classification systems like PTNM that help facilitate ...
Justin K. Achua, William A. Brown, Beatriz S. Hernandez, Thiago Pardini Furtado, Mohit Khera, Jeffrey C. Morrison   +5 more
wiley   +1 more source