Results 91 to 100 of about 32,892 (194)

Hit‐To‐Lead Optimization of a Pyridylpiperazine Class Against Malaria: Pharmacokinetic Profile and In Vivo Efficacy of Optimized Compounds

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Chemical optimization of a novel pyridylpiperazine class yields two promising antimalarial candidates with an exceptional balance of metabolic stability and solubility. These optimized leads significantly protect mice from cerebral malaria, reducing parasitic load by up to 91.7%.
Douglas Davison da Silva Oliveira, Duarte Eduardo Pereira, Rafael Consolin Chelucci, Simone Michelan, Júlia Maria Fernandes Pituba, Adriano D. Andricopulo, Leonardo L. G. Ferreira, Neide Maria Silva, Celso de Oliveira Rezende Júnior   +8 more
wiley   +1 more source

Chronopharmacology of verapamil in Stage I-II arterial hypertension

Кардиоваскулярная терапия и профилактика, 2009
Aim. To compare the pharmacokinetics and pharmacodynamics of verapamil retard, regularly taken by patients  with Stage I-II arterial hypertension (AH). Material and methods. The effects of the administration time (morning vs. evening) on verapamil retard
V. G. Belolipetskaya, D. F. Guranda, E. Yu. Fedorova, V. M. Gorbunov, N. A. Belolipetsky, A. V. Zhezlova, O. Yu. Isaykina, E. A. Zhabina, I. E. Koltunov   +8 more
doaj  

Successful Treatment of Rapid Cycling Bipolar Disorder With Lurasidone, Clozapine, and Valproate: A Case Report

Bipolar Disorders, Volume 28, Issue 5, August 2026.
Petr Potměšil, Miloslav Kopeček, Veronika Andrashko   +2 more
wiley   +1 more source

Cardioprotective Effect of Aloin Against Ischemia/Reperfusion Injury: Experimental and Computational POM Approaches. [PDF]

J Biochem Mol Toxicol
Kadi M, Hadda TB, Almalki FA, Mohammed NM, Abdelhady MIS, Ibrahim RR, Mishra AP, Babalghith AO, Bhat AR, Ahmed S, Ziyyat A, Legssyer A, Hajam YA.   +12 more
europepmc   +1 more source

The Potential Role of Verapamil Against Fluconazole-Induced Torsade de Pointes: A Critical Review. [PDF]

Health Sci Rep
Abdel-Razik NE, Al-Kuraishy HM, Al-Gareeb AI, Soliman MM, Alexiou A, Papadakis M, Aluwaili M, Batiha GE.   +7 more
europepmc   +1 more source

A Case of Wide Complex Tachycardia With Right Bundle Branch Block-Electrocardiographic Features to Distinguish Supraventricular Tachycardia With Aberrancy Versus Ventricular Tachycardia. [PDF]

J Arrhythm
Moe MEE, Loo G, Chong D, Ching KC.
europepmc   +1 more source

A clue hidden in plain sight. [PDF]

Eur Heart J Case Rep
Faheem Y, Merves S, Almasri M.
europepmc   +1 more source

Drug Repurposing of Verapamil for H1N1 Influenza Virus Infection: A Multi-Target Strategy Revealed by Network Pharmacology and Experimental Validation. [PDF]

Int J Mol Sci
Cao Y, Wu J, Li X, Qiu F, Wang S, Qian B, Fan L, Wang Y, Xue K, Zhang J, Shen B, Gao Y.   +11 more
europepmc   +1 more source

Identification of efflux inhibitors through a drug repurposing strategy in <i>Candida albicans</i>. [PDF]

Front Cell Infect Microbiol
Marques D, Costa SS, Rodrigues L.
europepmc   +1 more source

Comparison of Landiolol and Verapamil for Postoperative Atrial Fibrillation: A Prospective Randomized Study. [PDF]

Circ Rep
Yabu N, Minami T, Yasuda S, Kobayashi Y, Saito A.   +4 more
europepmc   +1 more source