Results 81 to 90 of about 46,600 (231)

Verapamil in Bipolar Illness

, 1986
The authors report two cases of Bipolar Affective Disorder which were responsive to Lithium therapy in the past, but could no longer be treated with Lithium due to hyperparathyroidism in the first case and noncompliance in the second.
Leigh Solomon, Peter Williamson
core   +1 more source

Calcium Channel Blocker Verapamil Enhances Reticulum Stress and Death Induced by Proteasome Inhibition in Myeloma Cells

Neoplasia: An International Journal for Oncology Research, 2010
The proteasome inhibitor bortezomib is clinically approved for the treatment of multiple myeloma. However, long-term remissions are difficult to achieve, and myeloma cells often develop secondary resistance to proteasome inhibitors.
Silke Meister, Benjamin Frey, Veronika R. Lang, Udo S. Gaipl, Georg Schett, Ursula Schlötzer-Schrehardt, Reinhard E. Voll   +6 more
doaj   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, EarlyView.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

Study on the performance and mechanism of verapamil degradation by zero-valent iron activated persulfate oxidation

Desalination and Water Treatment
Pharmaceuticals and personal care products (PPCPs) are a kind of refractory organic pollutants with large amount and wide range of pollution in environmental water, which can contaminate drinking water sources.
Xingya Wei, Weimin Geng, Bangjun Han, Renzheng Gu, Nana Li, Naiyun Gao   +5 more
doaj   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Effect of verapamil on QT interval dynamicity

, 1999
International audienceUsing measurements of QT/RR slopes with a computerized Holter system, QT interval dynamicity was evaluated in 19 patients with normal structural heart before and 2 months after oral treatment with verapamil prescribed for paroxysmal
Poret, Philippe, Fauchier, Jean Paul, Babuty, Dominique, Jean Paul Fauchier, Fauchier, Laurent, Philippe Poret, Marie Laurence Autret, Pierre Cosnay, Cosnay, Pierre, Dominique Babuty, Autret, Marie Laurence, Laurent Fauchier   +11 more
core   +1 more source

A comparative study of embedded and anesthetized zebrafish in vivo on myocardiac calcium oscillation and heart muscle contraction

Frontiers in Pharmacology, 2010
The zebrafish (Danio rerio) has been used as a model for studying vertebrate development in the cardiovascular system. In order to monitor heart contraction and cytosolic calcium oscillations, fish were either embedded in methylcellulose or anesthetized
Brian eMuntean, Christine Horvat, James Behler, Wissam AbouAlaiwi, Andromeda Nauli, Frederick Williams, Surya Nauli   +6 more
doaj   +1 more source

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

The Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones, Fiona S. Godbeer, Matthew K. Lancaster   +2 more
wiley   +1 more source

Effect of verapamil on human intestinal transit.

, 1992
Although constipation is a well-known side effect of calcium channel blockers such as verapamil, this side effect has not been evaluated in a quantitative manner.
Maurer, A H, Cohen, S, Krevsky, B, Niewiarowski, T   +3 more
core   +1 more source

Effects of verapamil combinations with enalapril or indapamide on plasma, vascular and platelet hemostasis and biochemical markers of endothelial dysfunction in patients with arterial hypertension and metabolic syndrome

Российский кардиологический журнал, 2008
The combination of verapamil retard and enalapril, or verapamil retard and indapamide SR similarly and significantly increased high-density lipoprotein cholesterol and stable NO2 metabolite levels, reducing platelet aggregation in patients with metabolic
N. M. Krasnova, T. P. Kalashnikova, A. I. Vengerovsky, E. M. Idrisova, I. V. Kulagina, T. E. Suslova, O. V. Gruzdeva, S. V. Kremeno, N. M. Zheltonogova, A. A. Shishkina, R. S. Karpov   +10 more
doaj