Results 71 to 80 of about 46,600 (231)

Verapamil treatment in severe Chironex fleckeri stings

open access: yes, 2004
[Extract] We thank Burnett and Calton for their interest in our work on Chironex fleckeri venom. However, we have significant concerns that they have focussed on the use of verapamil, and not discussed this in relation to the value of antivenom and ...
Ramasamy, Sharmaine   +3 more
core   +1 more source

Impact of Nebulized Verapamil in Patients with Pulmonary Hypertension Secondary to Lung Diseases

open access: yesAin Shams Medical Journal
Background: Pulmonary hypertension (PH) secondary to chronic lung diseases (CLD) remains a major therapeutic challenge, as systemic vasodilators may aggravate ventilation–perfusion mismatch and worsen hypoxemia.
Tamer Ibraheem   +3 more
doaj   +1 more source

Treatment strategies for interstitial granulomatous dermatitis: Systematic review and expert opinion

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
Systematic review of 108 studies with a total of 182 patients with interstitial granulomatous dermatitis (IGD). IGD was frequently associated with systemic conditions or drug exposure. Management includes careful medication review and prompt withdrawal of potential triggers. Corticosteroids (systemic and topical) were commonly effective, while biologic
Francesco Bellinato   +4 more
wiley   +1 more source

Comparison between Acute and Long-Term Effects of Verapamil on Naloxane Induced Morphine Withdrawal in Mice

open access: yesJournal of Research in Medical Sciences, 2004
Background: There is growing evidence indicating that neuronal calcium channels play an important role in the mechanism of Morphine dependence. Objective: To investigate the acute and long-term effects of Verapamil in Morphine dependent mice.
M Rabbani, A Jafarian, M Sobhanian
doaj  

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

open access: yesJournal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali   +4 more
wiley   +1 more source

Comparative Study of Protective Effect of Cimetidine and Verapamil on Paracetamol-Induced Hepatotoxicity in Mice

open access: yesInternational Journal of Hepatology, 2020
Paracetamol, chemically known as acetaminophen, if taken in higher doses has hepatotoxic potential. Cimetidine by inhibiting the cytochromal enzymes and reducing the production of the toxic metabolite can reduce the hepatotoxic potential while Verapamil ...
Lubna Danish   +5 more
doaj   +1 more source

Preliminary Comparison of Competitive Efflux and Historical Transwell Assays for Assessing Canine P‐Glycoprotein Substrate Status of Eleven Drugs Representing Ten Different Drug Classes

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Because P‐glycoprotein (P‐gp) influences the disposition of substrate drugs, regulatory agencies recommend ascertaining the P‐gp substrate status of active pharmaceutical ingredients (API's) intended for humans. Transwell‐based assays using P‐gp‐overexpressing human cell lines are routinely used to predict the API's P‐gp substrate status ...
K. L. Mealey, N. S. Burke
wiley   +1 more source

Verapamil-Associated Stevens-Johnson Syndrome

open access: yes, 1989
Stevens-Johnson syndrome (SJS) is a complication infrequently associated with the use of calcium-channel blocking agents. A 59-year-old woman developed symptoms typical of SJS approximately ten days following the initiation of sustained-release ...
Anne Y.F. Lin, Brian A. Baker
core   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

open access: yesPhotochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore   +6 more
wiley   +1 more source

Comparative effect and safety of verapamil in keloid and hypertrophic scar treatment: a meta-analysis

open access: yes, 2016
Zhouna Li, Zhehu Jin Department of Dermatology, Yanbian University Affiliated hospital, Yanji, Jilin, People’s Republic of China Background: Keloids and hypertrophic scars are the most common types of pathological scarring. Traditionally, keloids
Li ZN, Jin ZH
core  

Home - About - Disclaimer - Privacy