Results 101 to 110 of about 46,600 (231)
Interpatient variability with the disposition of verapamil
, 1997 The pharmacokinetics of verapamil were evaluated in the young and elderly after steady state administration of a sustained release formulation. The objective was to determine whether the interindividual metabolic variability of verapamil and its main ...
Anacleto, Ana Isabel.
core
Population Pharmacokinetic Analysis of Brensocatib in Adult and Adolescent Patients With Non‐Cystic Fibrosis Bronchiectasis [PDF]
CPT Pharmacometrics Syst PharmacolABSTRACT Brensocatib, a competitive and reversible oral DPP1 inhibitor, at 10 and 25 mg significantly reduced pulmonary exacerbation burden, and 25 mg also reduced lung function decline vs. placebo in patients with non‐cystic fibrosis bronchiectasis, hereafter bronchiectasis, in ASPEN (NCT04594369).
Usansky H +8 more
europepmc +2 more sources
Trends in Urology &Men's Health, Volume 17, Issue 5, October 2026.ABSTRACT Peyronie's disease significantly affects sexual function and psychological well‐being. It can lead to penile curvature, erectile dysfunction, and psychological distress—making the evaluation of quality of life through patient‐reported outcomes (PROs) essential. Therefore, this study sought to (1) describe the characteristics of RCTs evaluating
Thriaksh Rajan +5 more
wiley +1 more source
In vivo measurement of [11C]verapamil kinetics in human tissues
, 2001 Objectiva: To evaluate [11C]verapamil kinetics in humans. Methods: After intravenous injection of [11C]verapamil (370 MBq, specific activity >1600 GBq/mmol), kinetics were evaluated in five cancer patients using positron emission tomography (PET ...
De Vries, E. G.E. +4 more
core +1 more source
Indian Journal of Endocrinology and Metabolism, 2017 Resham Raj Poudel, Nisha Kusum Kafle
openaire +3 more sources
ChemMedChem, Volume 21, Issue 18, 28 September 2026.The acid‐sensing ion channel 3 (ASIC3), physiologically located in the peripheral nervous system, was found in stem cells of CNS‐located glioblastoma multiforme (GBM CSCs); its chronic activation in the CNS kills dysfunctional GBM CSCs with no effect on ASIC3‐lacking CNS tissues.
Leonardo Maiorana +8 more
wiley +1 more source
Advanced Science, Volume 13, Issue 53, 24 September 2026.This work establishes a novel method for generating multicellular liver organoids from control and MASH donor iPSCs. The model recapitulates several disease‐specific characteristics, with MASH donor‐derived organoids showing higher susceptibility. Lipidomic profiling of MASH organoids closely resembles MASH liver biopsies.
Ekta Minocha +5 more
wiley +1 more source
Brain and Behavior, Volume 16, Issue 9, September 2026.ABSTRACT Objective To determine whether patients with reversible cerebral vasoconstriction syndrome (RCVS) without demonstrable vasoconstriction differ clinically from those with angiographically confirmed vasoconstriction. Methods We retrospectively studied consecutive patients with RCVS hospitalized at a tertiary headache center in Japan between ...
Katsuya Takeuchi +8 more
wiley +1 more source
EMERGENCY TREATMENT OF SVT: ADENOSINE VERSUS VERAPAMIL
Journal of University Medical & Dental College, 2017 : Introduction: Supraventricular tachycardia (SVT) is a common arrhythmia seen in critical care settings. After vagal maneuvers, adenosine 6 to 12 mg intravenous bolus is the initial drug of choice.
Naeem Asghar +2 more
doaj
Cardiovascular effects of verapamil in patients with essential hypertension.
, 1987 The cardiovascular effects of intravenous verapamil and 3 months of oral administration of a slow-release form of verapamil (verapamil-SR) were studied in 10 patients with mild-to-moderate essential hypertension.
F H Messerli +3 more
core +1 more source