Results 121 to 130 of about 78,658 (276)

Magnesium Sulfate Combination Therapy for Aconitine‐Induced Electrical Storm

open access: yesAnnals of Noninvasive Electrocardiology, Volume 30, Issue 6, November 2025.
Treatment course of 28 episodes of electrical storm caused by aconitine poisoning with combined magnesium sulfate therapy. ABSTRACT We present the case of a 74‐year‐old man who developed 28 episodes of electrical storm secondary to aconitine poisoning from homemade herbal wine consumption, followed by complete recovery through 28 electrical ...
Liujiang Ran, Jun Si, Yanyan Liu
wiley   +1 more source

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

Structure‐based discovery of thiamine uptake inhibitors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 22, Page 5611-5626, November 2025.
Background and Purpose Thiamine (vitamin B1) is an essential coenzyme and catalyses various reactions in central metabolic pathways. Since mammals have lost the ability to synthesise thiamine de novo, this micronutrient has to be imported via the high affinity solute carriers SLC19A2 and A3 across the plasma membrane.
Florian Gabriel   +2 more
wiley   +1 more source

Preincisional and Postincisional Epidural Bupivacaine, Ketamin and Verapamil Effects on Postoperative Analgesic Consumption in Knee Replacement Surgery

open access: yesAnkara Üniversitesi Tıp Fakültesi Mecmuas, 2011
Patients and method: 164 patients undergoing total knee arthroplasty were randomly divided into 8 groups. The study groups are, group 1 (preB), preincisional bupivacaine, postincisional saline; group 2 (postB), preincisional saline, postincisional ...
Enver Özgencil   +3 more
doaj   +1 more source

IA‐0130, a novel 3‐(1,3‐diarylallylidene)oxindole derivative, alleviates ovarian cancer via inhibiting IL‐6/gp130/STAT3 signalling

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 22, Page 5670-5689, November 2025.
Background and Purpose Dysregulation of the IL‐6/glycoprotein 130(gp130)/STAT3 signalling axis is implicated in several human diseases, particularly cancer. Notably, gp130, a single transducer of this signalling axis, is a target for ovarian cancer treatment. However, data regarding small‐molecule inhibitors of gp130 are lacking. Therefore, we aimed to
Sun‐Ae Park   +11 more
wiley   +1 more source

CORDARONE AND VERAPAMIL EFFECTIVENESS IN PRE-HOSPITAL TREATMENT OF ATRIAL FIBRILLATION PAROXYSMS

open access: yesРоссийский кардиологический журнал, 2009
In 263 patients with atrial fibrillation lasting for 0,5–30 hours, pre-hospital antiarrythmic therapy (cordarone 5 mg/kg, verapamil 5–10 mg) was ineffective in the first hour.
V. G. Epifanov   +3 more
doaj  

Non‐Invasive Vagus Nerve Stimulation in Cluster Headache: A Clinical Practice Guideline

open access: yesPain Practice, Volume 25, Issue 8, November 2025.
ABSTRACT Background Cluster headache (CH) is a rare but severe primary headache disorder characterized by recurrent attacks of unilateral, typically periocular pain lasting 15 min to 3 h, accompanied by ipsilateral autonomic symptoms and restlessness or agitation.
Peter J. Goadsby   +4 more
wiley   +1 more source

Verapamil in diabetes

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Nisha Kusum Kafle, Resham Raj Poudel
openaire   +4 more sources

New Mechanisms for Regulation of Intracellular Collagen Degradation in Fibrotic Lesions of Periodontal Tissues

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Drug‐induced gingival overgrowth involves dysregulation of intracellular collagen degradation. The mechanisms that are involved in the regulation of lysosomal collagenolytic activity are poorly understood. Here, we focus on how cathepsins, Rabs, and V‐ATPases regulate intracellular collagen degradation and, in particular, the vesicular trafficking and ...
Wing Hei Wong   +3 more
wiley   +1 more source

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