Results 111 to 120 of about 271,842 (268)

Verification Technology for Object-Oriented/XML Transactions

, 2009
Typically, object-oriented schemas are lacking declarative specification of the schema integrity constraints. Object-oriented transactions are also typically missing a fundamental ACID requirement: consistency.
Royer, Mark, Alagić, Suad, PhD, Briggs, David, PhD   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

On the Functional Verification of Dynamic Partial Reconfiguration

, 2018
Dynamic Partial Reconfiguration (DPR) on Field Programmable Gate Arrays (FPGAs) allows reconfiguration of some of the logic at runtime while the rest of the logic keeps operating.
Ahmed Nader Mohieldin, Ahmed, Islam, Mostafa, Hassan, Mohieldin, Ahmed Nader, Hassan Mostafa, Islam Ahmed   +5 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Gene replacement therapy in Bietti crystalline corneoretinal dystrophy: an open-label, single-arm, exploratory trial

Signal Transduction and Targeted Therapy
Bietti crystalline corneoretinal dystrophy is an inherited retinal disease caused by mutations in CYP4V2, which results in blindness in the working-age population, and there is currently no available treatment. Here, we report the results of the first-in-
Jinyuan Wang, Jinlu Zhang, Shicheng Yu, Hongyan Li, Shaohong Chen, Jingting Luo, Haibo Wang, Yuxia Guan, Haihan Zhang, Shiyi Yin, Huili Wang, Heping Li, Junle Liu, Jingyuan Zhu, Qiong Yang, Ying Sha, Chuan Zhang, Yuhang Yang, Xuan Yang, Xifang Zhang, Xiuli Zhao, Likun Wang, Liping Yang, Wenbin Wei   +23 more
doaj   +1 more source

A synthesis of fuzzy rule-based system verification. [PDF]

The verification of fuzzy rule bases for anomalies has received increasing attention these last few years. Many different approaches have been suggested and many are still under investigation.
Vanthienen, Jan, Wets, G, Viaene, Stijn
core  

MISAT: Designing a Series of Powerful Small Satellites Based upon Micro Systems Technology [PDF]

, 2007
MISAT is a research and development cluster which will create a small satellite platform based on Micro Systems Technology (MST) aiming at innovative space as well as terrestrial applications.
Verhoeven, C.J.M., Verhoeven, C.J.M.,, Scherpen, J.M.A.,, Gill, E.,, Scherpen, J.M.A., Monna, G.L.E., Gill, E., Monna, G.L.E.,   +7 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Platform-based design, test and fast verification flow for mixed-signal systems on chip

, 2011
This research is providing methodologies to enhance the design phase from architectural space exploration and system study to verification of the whole mixed-signal system.
CECCHINI, TOMMASO
core  

Bayesian distance metric learning on i-vector for speaker verification [PDF]

, 2013
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2013.Cataloged from PDF version of thesis.Includes bibliographical references (pages 63-66).This thesis explores the use of Bayesian distance ...
Fang, Xiao, Ph. D. Massachusetts Institute of Technology
core