Results 61 to 70 of about 72,292 (222)

Microalgal metabolites as anti-cancer/anti-oxidant agents reduce cytotoxicity of elevated silver nanoparticle levels against non-cancerous vero cells

Heliyon, 2020
Heavy metal pollution has become a major concern globally as it contaminates eco-system, water networks and as finely suspended particles in air. In this study, the effects of elevated silver nanoparticle (AgNPs) levels as a model system of heavy metals,
Hanaa Ali Hussein, M. Maulidiani, Mohd Azmuddin Abdullah   +2 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

VP1-141 is a determinant of a Vero cell-adapted Coxsackievirus A10 for vaccine development.

PLoS Neglected Tropical Diseases
Coxsackievirus A10 (CVA10) infection primarily causes hand, foot, and mouth diseases (HFMD) in children. As CVA10 is one of the most widespread enteroviruses, the development of a CVA10 vaccine is essential.
Chi-Hsun Chen, Chih-Yeu Fang, Yu-Sheng Shen, Jen-Ren Wang, Suh-Chin Wu, Chia-Chyi Liu   +5 more
doaj   +1 more source

Fluoroquinolone Antibiotics Exhibit Low Antiviral Activity against SARS-CoV-2 and MERS-CoV

Viruses, 2020
Repurposing FDA-approved drugs that treat respiratory infections caused by coronaviruses, such as SARS-CoV-2 and MERS-CoV, could quickly provide much needed antiviral therapies.
Stacey L. P. Scroggs, Danielle K. Offerdahl, Dylan P. Flather, Ciera N. Morris, Benjamin L. Kendall, Rebecca M. Broeckel, Paul A. Beare, Marshall E. Bloom   +7 more
doaj   +1 more source

Scan‐Path‐ and Initial‐State‐Dependent Superdomain Switching in (111)‐Oriented PZT

Advanced Electronic Materials, EarlyView.
Scan trajectory and initial superdomain topology govern polarization switching in (111)‐oriented PZT. Automated AFM writing, pulsing experiments, and interferometric 3D‐PFM show that raster scans reproducibly stabilize ordered Type‐I stripe superdomains with constrained variant selection, whereas spiral trajectories generate frustrated mixed‐variant ...
Rama Vasudevan, Laveeza Ahmad, Bharat Pant, Ralph Bulanadi, Asraful Haque, Puneet Kaur, Sabine Neumayer, Jan‐Chi Yang, Yongtao Liu, Ye Cao, Stephen Jesse, Marti Checa   +11 more
wiley   +1 more source

Cooptimized Sensing and Sole Mechanics Enable Embodied‐Intelligence Design of User‐Specific Smart Footwear

Advanced Intelligent Systems, EarlyView.
An embodied codesign framework for smart footwear is presented, jointly tuning lattice mechanics and sensing for personalized plantar pressure monitoring. By integrating pneumatic sensing within 3D‐printed lattice soles, the system achieves accurate real‐time centre‐of‐pressure tracking with reduced sensor count and energy demand, demonstrating how ...
Fengyu Zhong, Marco Pontin, Amy Zavatsky, Perla Maiolino   +3 more
wiley   +1 more source

Comparing chemical transfection, electroporation, and lentiviral vector transduction to achieve optimal transfection conditions in the Vero cell line

BMC Molecular and Cell Biology
Background Transfection is an important analytical method for studying gene expression in the cellular environment. There are some barriers to efficient DNA transfection in host cells, including circumventing the plasma membrane, escaping endosomal ...
Parisa Jamour, Abbas Jamali, Arash Ghalyanchi Langeroudi, Behrouz Ebadi Sharafabad, Asghar Abdoli   +4 more
doaj   +1 more source

Adaptation of high-growth influenza H5N1 vaccine virus in Vero cells: implications for pandemic preparedness. [PDF]

PLoS ONE, 2011
Current egg-based influenza vaccine production technology can't promptly meet the global demand during an influenza pandemic as shown in the 2009 H1N1 pandemic.
Yu-Fen Tseng, Alan Yung-Chih Hu, Mei-Liang Huang, Wei-Zhou Yeh, Tsai-Chuan Weng, Yu-Shuan Chen, Pele Chong, Min-Shi Lee   +7 more
doaj   +1 more source

Interaction between submicron COD crystals and renal epithelial cells

International Journal of Nanomedicine, 2012
Hua Peng1,2 Jian-Ming Ouyang1,2 Xiu-Qiong Yao1, Ru-E Yang11Department of Chemistry, Jinan University, 2Institute of Biomineralization and Lithiasis Research, Jinan University, Guangzhou, ChinaObjectives: This study aims to investigate the adhesion ...
Peng H, Ouyang JM, Yao XQ, Yang RE
doaj  

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source