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Very Long-Chain Fatty Acids in Peroxisomal Disease
1992Fatty acids with from 24 to 28 carbon atoms (very long-chain fatty acids, VLCFA) are present in small amounts in all mammalian tissues. Even longer chain fatty acids with from 30 to 38 carbon atoms (ultra-long-chain fatty acids, ULCFA) are found in certain specialized tissues including retina, brain, and spermatozoa.
A, Poulos +7 more
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Extending the story of very-long-chain fatty acid elongation
Plant Science, 2013Very-long-chain fatty acids (VLCFAs) are essential molecules produced by all plant cells, and are components or precursors of numerous specialized metabolites synthesized in specific cell types. VLCFAs are elongated by an endoplasmic reticulum-localized fatty acid elongation complex of four core enzymes, which sequentially add two carbon units to a ...
Tegan M, Haslam, Ljerka, Kunst
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Very long chain fatty acid oxidation in rat liver
Biochemical and Biophysical Research Communications, 1981Abstract [l- 14 C]Lignoceric acid (C24:0) was oxidized to CO 2 and water-soluble intermediates by rat liver preparations. With mitochondria alone, the radioactivity in the water-soluble material increased rapidly for the first 10 min, then decreased, while 14 CO 2 appeared only after the 10 min lag.
N, Kawamura, H W, Moser, Y, Kishimoto
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Very-Long-Chain Fatty Acids and Phytanic Acid
2008The peroxisomes are subcellular organelles with a variety of biochemical functions, amongst which a system for beta-oxidation of very long-chain (C22-C26) fatty acids (VLCFA) and a system for alpha-oxidation of branched-chain fatty acids such as phytanic acid.
Wanders, R. J. A., Duran, M.
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Very-long-chain fatty acids from lower organism
Folia Microbiologica, 1987The qualitative occurrence and quantitative proportion of very-long-chain fatty acids (above C22), mainly in lower organisms and briefly in higher plants and animals is described.
T, Rezanka, J, Cudlín, M, Podojil
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Very Long Chain Fatty Acid Synthesis in Sunflower Kernels
Journal of Agricultural and Food Chemistry, 2005Most common seed oils contain small amounts of very long chain fatty acids (VLCFAs), the main components of oils from species such as Brassica napus or Lunnaria annua. These fatty acids are synthesized from acyl-CoA precursors in the endoplasmic reticulum through the activity of a dissociated enzyme complex known as fatty acid elongase.
Joaquín J, Salas +2 more
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Dissociation of Long and Very Long Chain Fatty Acids from Phospholipid Bilayers
Biochemistry, 1996Dissociation of fatty acids (FA) from and transbilayer movement (flip-flop) in small unilamellar phosphatidylcholine vesicles (SUV) were monitored by measuring the pH inside the vesicle with an entrapped water-soluble fluorophore, pyranin. With a pH gradient imposed upon SUV preloaded with FA, the rate of flip-flop of saturated very long chain FA (C20 ...
F, Zhang, F, Kamp, J A, Hamilton
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Very long chain fatty acids in higher animals—A review
Lipids, 1995AbstractFatty acids with greater than 22 carbon atoms (very long chain fatty acids, VLCFA) are present in small amounts in most animal tissues. Saturated and monoenoic VLCFA are major components of brain, while the polyenoic VLCFA occur in significant amounts in certain specialized animal tissues such at retina and spermatozoa.
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Inhibitors of Biosynthesis of Very-Long-Chain Fatty Acids
2002Chloroacetamides have been used in maize, soybean or rice for about 50 years (Hamm 1974). During 1997/1998 in the USA, this class contributed to about 50% of the herbicides applied in corn and 11% in soybean (Anonymous 1999). Safeners have successfully broadened their use, and postemergence weed treatment has been improved by the concurrent application
Peter Böger, Bernd Matthes
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The Role of Long-Chain Polyunsaturated Fatty Acids in Very Preterm Nutrition
2022Infants born very preterm miss out on the in utero transfer of the omega-3 and omega-6 long-chain polyunsaturated fatty acids that occurs during the third trimester. A number of studies have explored the impact of increasing the enteral intakes of omega-3 +/- omega-6 long-chain polyunsaturated fatty acids to match fetal accretion rates in such infants.
Andrew J, McPhee +3 more
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