Results 1 to 10 of about 380,048 (349)

Accuracy of low-density lipoprotein cholesterol estimation at very low levels [PDF]

BMC Medicine, 2017
Background As the approach to low-density lipoprotein cholesterol (LDL-C) lowering becomes increasingly intensive, accurate assessment of LDL-C at very low levels warrants closer attention in individualized clinical efficacy and safety evaluation.
Renato Quispe, Aditya Hendrani, Mohamed B. Elshazly, Erin D. Michos, John W. McEvoy, Michael J. Blaha, Maciej Banach, Krishnaji R. Kulkarni, Peter P. Toth, Josef Coresh, Roger S. Blumenthal, Steven R. Jones, Seth S. Martin   +12 more
doaj   +5 more sources

Emerging Evidence of Pathological Roles of Very-Low-Density Lipoprotein (VLDL) [PDF]

Int J Mol Sci, 2022
Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours.
Jih-Kai Huang, Hsiang-Chun Lee
semanticscholar   +2 more sources

Is hypertriglyceridemic very low density lipoprotein a precursor of normal low density lipoprotein?

Journal of Lipid Research, 1985
The precursor-product relationship of very low density (VLDL) and low density lipoproteins (LDL) was studied. VLDL obtained from normal (NTG) and hypertriglyceridemic (HTG) subjects was fractionated by zonal ultracentrifugation and subjected to in vitro ...
Y Oschry, T Olivecrona, R J Deckelbaum, S Eisenberg   +3 more
doaj   +3 more sources

PPARδ is a very low-density lipoprotein sensor in macrophages [PDF]

Proceedings of the National Academy of Sciences, 2003
Although triglyceride-rich particles, such as very low-density lipoprotein (VLDL), contribute significantly to human atherogenesis, the molecular basis for lipoprotein-driven pathogenicity is poorly understood. We demonstrate that in macrophages, VLDL functions as a transcriptional regulator via the activation of the nuclear receptor peroxisome ...
A. Chawla, Chih‐Hao Lee, Y. Barak, Weimin He, J. Rosenfeld, D. Liao, Jungyeob Han, Heonjoong Kang, R. Evans   +8 more
semanticscholar   +4 more sources

Low Very low-Density Lipoprotein Cholesterol but High Very low-Density Lipoprotein Receptor mRNA Expression in Peripheral White Blood Cells: An Atherogenic Phenotype for Atherosclerosis in a Community-Based Population [PDF]

EBioMedicine, 2017
Very low-density lipoprotein cholesterol (VLDL-C), via binding very low-density lipoprotein receptor (VLDLR), can induce the development of atherosclerosis.
Fan Zhao, Yue Qi, Jing Liu, Wei Wang, Wuxiang Xie, Jiayi Sun, Jun Liu, Yongchen Hao, Miao Wang, Yan Li, Dong Zhao   +10 more
doaj   +2 more sources

Interactions of high density lipoproteins with very low and low density lipoproteins during lipolysis.

Journal of Lipid Research, 1988
Interactions of high density lipoproteins (HDL) with very low (VLDL) and low (LDL) density lipoproteins were investigated during in vitro lipolysis in the presence of limited free fatty acid acceptor. Previous studies had shown that lipid products accumulating on lipoproteins under these conditions promote the formation of physical complexes between ...
Ming‐Shyan Lin, H J Michenfelder, R M Krauss   +2 more
openalex   +5 more sources

Delayed clearance of very low density and intermediate density lipoproteins with enhanced conversion to low density lipoprotein in WHHL rabbits.

Proceedings of the National Academy of Sciences of the United States of America, 1982
Rabbit livers express two genetically distinct receptors for plasma lipoproteins: (i) the low density lipoprotein (LDL) receptor and (ii) the chylomicron remnant receptor.
Tomoko Kita, M S Brown, D W Bilheimer, Joseph L. Goldstein   +3 more
openalex   +2 more sources

Discordance Between Very Low‐Density Lipoprotein Cholesterol and Low‐Density Lipoprotein Cholesterol Increases Cardiovascular Disease Risk in a Geographically Defined Cohort [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Clinical risk scores are used to identify those at high risk of atherosclerotic cardiovascular disease (ASCVD). Despite preventative efforts, residual risk remains for many individuals.
Kristina E. Seehusen, Alan T. Remaley, Maureen Sampson, Jeffrey W. Meeusen, Nicholas B. Larson, Paul A. Decker, Jill M. Killian, Paul Y. Takahashi, Véronique L. Roger, Sheila M. Manemann, Reyna Lam, Suzette J. Bielinski   +11 more
doaj   +2 more sources

Reticulon 3 regulates very low density lipoprotein secretion by controlling very low density lipoprotein transport vesicle biogenesis. [PDF]

Can J Physiol Pharmacol, 2018
Secretion of very low density lipoprotein (VLDL) by the liver is an important physiological process; however, the rate of VLDL secretion is determined by its transport from the endoplasmic reticulum (ER) to the Golgi. This transport event is facilitated by a specialized ER-derived vesicle, the VLDL transport vesicle (VTV).
Siddiqi S, Zhelyabovska O, Siddiqi SA.
europepmc   +5 more sources

Resistance of a very low density lipoprotein subpopulation from familial dysbetalipoproteinemia to in vitro lipolytic conversion to the low density lipoprotein density fraction.

Journal of Lipid Research, 1983
In vitro lipolysis of very low density lipoprotein (VLDL) from normolipidemic and familial dysbetalipoproteinemic plasma by purified bovine milk lipoprotein lipase was studied using the combined single vertical spin and vertical autoprofile method of ...
B H Chung, J P Segrest
doaj   +2 more sources