Results 71 to 80 of about 529,645 (391)
Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion
eLife, 2015 Recent evidence suggests that autophagy facilitates the unconventional secretion of the pro-inflammatory cytokine interleukin 1β (IL-1β). Here, we reconstituted an autophagy-regulated secretion of mature IL-1β (m-IL-1β) in non-macrophage cells.
M. Zhang +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Frequency-dependent electrodeformation of giant phospholipid vesicles in AC electric field [PDF]
J Biol Phys 36 (2010) 339-354, 2010 A model of vesicle electrodeformation is described which obtains a parametrized vesicle shape by minimizing the sum of the membrane bending energy and the energy due to the electric field. Both the vesicle membrane and the aqueous media inside and outside the vesicle are treated as leaky dielectrics, and the vesicle itself is modelled as a nearly ...
arxiv +1 more source
The Role of Mitochondrially Derived ATP in Synaptic Vesicle Recycling*♦
Journal of Biological Chemistry, 2015 Background: The ATP requirements of synaptic vesicle release are poorly understood. Results: Mitochondrially derived ATP supports the function of boutons with and without mitochondria.
D. Pathak +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
From Vesicles to Protocells: The Roles of Amphiphilic Molecules
Life, 2015 It is very challenging to construct protocells from molecular assemblies. An important step in this challenge is the achievement of vesicle dynamics that are relevant to cellular functions, such as membrane trafficking and self-reproduction, using ...
Yuka Sakuma, Masayuki Imai
doaj +1 more source
Adhesion of Multi-component Vesicle Membranes [PDF]
, 2009 In this work, we study the adhesion of multi-component vesicle membrane to both flat and curved substrates, based on the conventional Helfrich bending energy for multi-component vesicles and adhesion potentials of different forms. A phase field formulation is used to describe the different components of the vesicle.
arxiv +1 more source
Ready-made chromatography columns for extracellular vesicle isolation from plasma
Journal of Extracellular Vesicles, 2015 Proteomic studies of circulating vesicles are hampered by difficulties in purifying vesicles from plasma and serum. Isolations are contaminated with high-abundance blood proteins that may mask genuine vesicular-associated proteins and/or simply provide ...
Joanne L Welton +4 more
semanticscholar +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Translocation of a daughter vesicle in a model system of self-reproducing vesicles [PDF]
arXiv, 2023 Translocation of a daughter vesicle from a mother vesicle through a pore is experimentally studied by many groups using a model system of self-reproducing vesicles. However, the theoretical formulation of the problem is not fully understood. In the present study, we present a theoretical formulation of the process based on our previous work [P ...
arxiv