Results 71 to 80 of about 521,692 (352)
From Vesicles to Protocells: The Roles of Amphiphilic Molecules
Life, 2015 It is very challenging to construct protocells from molecular assemblies. An important step in this challenge is the achievement of vesicle dynamics that are relevant to cellular functions, such as membrane trafficking and self-reproduction, using ...
Yuka Sakuma, Masayuki Imai
doaj +1 more source
Journal of Systems Chemistry, 2011 While studying fatty acid vesicles as model primitive cell membranes, we encountered a dramatic phenomenon in which light triggers the sudden rupture of micron-scale dye-containing vesicles, resulting in rapid release of vesicle contents. We show that such vesicle explosions are caused by an increase in internal osmotic pressure mediated by the ...
Ting F. Zhu, Jack W. Szostak
openaire +2 more sources
Charge-Reversal Instability in Mixed Bilayer Vesicles
, 2000 Bilayer vesicles form readily from mixtures of charged and neutral surfactants. When such a mixed vesicle binds an oppositely-charged object, its membrane partially demixes: the adhesion zone recruits more charged surfactants from the rest of the ...
A. D. Dinsmore +24 more
core +2 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
eLife, 2014 The Drosophila protocadherin Fat (Ft) regulates growth, planar cell polarity (PCP) and proximodistal patterning. A key downstream component of Ft signaling is the atypical myosin Dachs (D).
Justin A Bosch +5 more
doaj +1 more source
Vesicle dynamics in elongation flow: Wrinkling instability and bud formation
, 2007 We present experimental results on the relaxation dynamics of vesicles subjected to a time-dependent elongation flow. We observed and characterized a new instability, which results in the formation of higher order modes of the vesicle shape (wrinkles ...
Enrico Segre +3 more
core +1 more source
Selective flow-induced vesicle rupture to sort by membrane mechanical properties [PDF]
, 2015 International audienceVesicle and cell rupture caused by large viscous stresses in ultrasonication is central to biomedical and bioprocessing applications.
Brooks, NJ +3 more
core +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
FEBS Letters, EarlyView.Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos +3 more
wiley +1 more source
A Fusion–Growth Protocell Model Based on Vesicle Interactions with Pyrite Particles
MoleculesProtocell models play a pivotal role in the exploration of the origin of life. Vesicles are one type of protocell model that have attracted much attention.
Dong Guo +5 more
doaj +1 more source
Vesicle dynamics in confined steady and harmonically modulated Poiseuille flows
, 2018 We present a numerical study of the time-dependent motion of a two-dimensional vesicle in a channel under an imposed flow. In a Poiseuille flow the shape of the vesicle depends on the flow strength, the mechanical properties of the membrane, and the ...
Benyoussef, Abdelilah +6 more
core +1 more source