Results 241 to 250 of about 1,227,442 (389)

Reexamination of N-terminal domains of syntaxin-1 in vesicle fusion from central murine synapses. [PDF]

open access: yesElife, 2021
Vardar G   +7 more
europepmc   +1 more source

Drosophila CAPS Is an Essential Gene that Regulates Dense-Core Vesicle Release and Synaptic Vesicle Fusion [PDF]

open access: bronze, 2001
Robert Renden   +8 more
openalex   +1 more source

Engineered Foxp1high Exosomes Ameliorates Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
This study presents a dual‐engineering strategy combining mesenchymal stem cell aggregation and Foxp1 overexpression to generate Foxp1high aggregation exosomes with enhanced immunomodulatory properties. These engineered exosomes exhibit immune organ targeting and superior efficacy in systemic lupus erythematosus treatment by promoting Treg ...
Luhan Niu   +9 more
wiley   +1 more source

Reconstitution of Membrane Proteins into Giant Unilamellar Vesicles via Peptide-Induced Fusion [PDF]

open access: bronze, 2001
Nicoletta Kahya   +4 more
openalex   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao   +7 more
wiley   +1 more source

Adducin‐1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity

open access: yesAdvanced Science, EarlyView.
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang   +10 more
wiley   +1 more source

Mutations of Single Residues in the Complexin N-terminus Exhibit Distinct Phenotypes in Synaptic Vesicle Fusion. [PDF]

open access: yesJ Neurosci
Toulme E   +8 more
europepmc   +1 more source

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