Results 251 to 260 of about 1,227,442 (389)

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Vesicle-vesicle fusion promoted by the Atg8-family autophagy protein LC3C: relevance of the N-terminal region. [PDF]

Autophagy
Ballesteros U, Alonso A, Montes LR, Etxaniz A.   +3 more
europepmc   +1 more source

Syntaxin 7, syntaxin 8, Vti1 and VAMP7 (vesicle-associated membrane protein 7) form an active SNARE complex for early macropinocytic compartment fusion in Dictyostelium discoideum [PDF]

, 2002
Aleksandra Bogdanović, Nelly Bennett, Sylvie Kieffer, Mathilde Louwagie, Takahiro Morio, Jérôme Garin, Michel Satre, Franz Brückert   +7 more
openalex   +1 more source

Comparative Analysis of Clinical Outcomes and Financial Aspects of Phototherapies and Immunotherapy for Cancer

Advanced Science, EarlyView.
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan, Kun Shao, Roopa Hebbandi Nanjundappa, Daniel‐Jiajun Yu, Marianne Stanford, Huile Gao, Channakeshava Sokke Umeshappa   +6 more
wiley   +1 more source

Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion. [PDF]

Proc Natl Acad Sci U S A
López-Murcia FJ, Lin KH, Berns MMM, Ranjan M, Lipstein N, Neher E, Brose N, Reim K, Taschenberger H.   +8 more
europepmc   +1 more source

Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity

Advanced Science, EarlyView.
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang, Yesheng Fu, Lihua Qiang, Mengyuan Zhao, Zhe Lu, Zhuo Zhao, Guoping Chen, Zehui Lei, Qiyao Chai, Pupu Ge, Bingxi Li, Jing Wang, Cui Hua Liu, Lingqiang Zhang   +13 more
wiley   +1 more source

The role of extracellular vesicle fusion with target cells in triggering systemic inflammation. [PDF]

Nat Commun
Papareddy P, Tapken I, Kroh K, Varma Bhongir RK, Rahman M, Baumgarten M, Cim EI, Györffy L, Smeds E, Neumann A, Veerla S, Olinder J, Thorlacus H, Ryden C, Bartakova E, Holub M, Herwald H.   +16 more
europepmc   +1 more source

Fusion of vesicles with the air–water interface: the influence of polar head group, salt concentration, and vesicle size

, 2000
Marcos Gugliotti, Hernán Chaimovich, Mário J. Politi   +2 more
openalex   +1 more source

Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons

Journal of Neuroscience, 2016
Gülçin Vardar, Shuwen Chang, M. Arancillo, Yuan-Ju Wu, T. Trimbuch, Christian Rosenmund   +5 more
semanticscholar   +1 more source

Orosomucoid 1 Ameliorates Temporomandibular Joint Osteoarthritis by Maintaining Cartilage Homeostasis

Advanced Science, EarlyView.
The present study identified the key protein ORM1 through the proteomic analysis of synovial fluid samples from patients with temporomandibular joint osteoarthritis (TMJOA), and demonstrated the important role of ORM1 in maintaining cartilage homeostasis via the suppression of VIM/MAPK/MMP signalling.
Dahe Zhang, Yuxin Zhang, Simo Xia, Lu Chen, Pei Shen, Chi Yang   +5 more
wiley   +1 more source