Results 31 to 40 of about 151,771 (292)
Neurobiology of Disease, 2003 Loss of synapses correlates with cognitive decline in Alzheimer’s disease (AD). However, molecular mechanisms underlying the synaptic dysfunction and loss are not well understood.
Pamela J Yao +6 more
doaj +1 more source
Bio-Protocol, 2021 More than 30% of the total amount of proteins synthesized in mammalian cells follow the secretory pathway in order to mature and be properly sorted to their final destinations.
Mehrshad Pakdel +2 more
doaj +1 more source
Early stages of retinal development depend on Sec13 function [PDF]
, 2013 Summary ER-to-Golgi transport of proteins destined for the extracellular space or intracellular compartments depends on the COPII vesicle coat and is constitutive in all translationally active cells.
Cavodeassi, Florencia +3 more
core +3 more sources
Rab GTPases: Central Coordinators of Membrane Trafficking in Cancer
Frontiers in Cell and Developmental Biology, 2021 Tumor progression involves invasion, migration, metabolism, autophagy, exosome secretion, and drug resistance. Cargos transported by membrane vesicle trafficking underlie all of these processes.
Hongyuan Jin +13 more
doaj +1 more source
Genome-Wide Association Study for Maize Leaf Cuticular Conductance Identifies Candidate Genes Involved in the Regulation of Cuticle Development. [PDF]
, 2020 The cuticle, a hydrophobic layer of cutin and waxes synthesized by plant epidermal cells, is the major barrier to water loss when stomata are closed at night and under water-limited conditions.
Baseggio, Matheus +12 more
core +2 more sources
Regulation of plasma membrane expansion during axon formation [PDF]
, 2018 Here, will review current evidence regarding the signaling pathways and mechanisms underlying membrane addition at sites of active growth during axon formation.Fil: Quiroga, Santiago. Consejo Nacional de Investigaciones Científicas y Técnicas.
Bisbal, Mariano +2 more
core +1 more source
Molecular Plant-Microbe Interactions, 2017 Vesicle trafficking is an important event in eukaryotic organisms. Many proteins and lipids transported between different organelles or compartments are essential for survival.
Bing Li +7 more
doaj +1 more source
Acta Neuropathologica Communications, 2017 While Munc18–1 interacts with Syntaxin1 and controls the formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) complex to regulate presynaptic vesicle fusion in developed neurons, this molecule is likely to be ...
Nanako Hamada +3 more
doaj +1 more source
A new vesicle trafficking regulator CTL1 plays a crucial role in ion homeostasis. [PDF]
PLoS Biology, 2017 Ion homeostasis is essential for plant growth and environmental adaptation, and maintaining ion homeostasis requires the precise regulation of various ion transporters, as well as correct root patterning.
Yi-Qun Gao +8 more
doaj +1 more source
Effects of Excess Brain-Derived Human α-Synuclein on Synaptic Vesicle Trafficking
Frontiers in Neuroscience, 2021 α-Synuclein is a presynaptic protein that regulates synaptic vesicle trafficking under physiological conditions. However, in several neurodegenerative diseases, including Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy, α ...
Cristina Román-Vendrell +5 more
doaj +1 more source