Results 21 to 30 of about 152,465 (288)
Advanced Science, 2023 Vesicle trafficking has emerged as an important process driving tumor progression through various mechanisms. Transforming growth factor beta (TGFβ)‐mediated secretion of Angiopoietin‐like 4 (ANGPTL4) is important for cancer development.
Dennis Frank +5 more
doaj +1 more source
"Alternative" endocytic mechanisms exploited by pathogens: new avenues for therapeutic delivery? [PDF]
, 2007 Some pathogens utilize unique routes to enter cells that may evade the intracellular barriers encountered by the typical clathrin-mediated endocytic pathway.
Medina-Kauwe, LK
core +1 more source
Structures of yeast vesicle trafficking proteins [PDF]
Protein Science, 1999 AbstractIn protein transport between organelles, interactions of v‐ and t‐SNARE proteins are required for fusion of proteincontaining vesicles with appropriate target compartments. Mammalian SNARE proteins have been observed to interact with NSF and SNAP, and yeast SNAREs with yeast homologues of NSF and SNAP proteins.
Tishgarten, T +7 more
openaire +3 more sources
Getting Sugar Coating Right! The Role of the Golgi Trafficking Machinery in Glycosylation
Cells, 2021 The Golgi is the central organelle of the secretory pathway and it houses the majority of the glycosylation machinery, which includes glycosylation enzymes and sugar transporters. Correct compartmentalization of the glycosylation machinery is achieved by
Zinia D’Souza +3 more
doaj +1 more source
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Crawford, Sue E. +4 more
core +2 more sources
Cell polarity and patterning by PIN trafficking through early endosomal compartments in Arabidopsis thaliana [PDF]
, 2013 PIN-FORMED (PIN) proteins localize asymmetrically at the plasma membrane and mediate intercellular polar transport of the plant hormone auxin that is crucial for a multitude of developmental processes in plants.
De Rycke, Riet +8 more
core +14 more sources
CK2 phosphorylates Sec31 and regulates ER-To-Golgi trafficking. [PDF]
PLoS ONE, 2013 Protein export from the endoplasmic reticulum (ER) is an initial and rate-limiting step of molecular trafficking and secretion. This is mediated by coat protein II (COPII)-coated vesicles, whose formation requires small GTPase Sar1 and 6 Sec proteins ...
Mayuko Koreishi +4 more
doaj +1 more source
Vesicle Trafficking: A Rab Family Profile [PDF]
Current Biology, 2011 A new tool-kit has been developed for profiling expression and function of Rab GTPases on a genome-wide scale. Use of this tool-kit has revealed unexpectedly that at least half of Drosophila Rabs have neuronal-specific expression patterns and localize to synapses.
Harris, Kathryn P., Littleton, J. Troy
openaire +3 more sources
Neurobiology of Disease, 2003 Loss of synapses correlates with cognitive decline in Alzheimer’s disease (AD). However, molecular mechanisms underlying the synaptic dysfunction and loss are not well understood.
Pamela J Yao +6 more
doaj +1 more source
Bio-Protocol, 2021 More than 30% of the total amount of proteins synthesized in mammalian cells follow the secretory pathway in order to mature and be properly sorted to their final destinations.
Mehrshad Pakdel +2 more
doaj +1 more source