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An Improved Method to Enrich Large Extracellular Vesicles Derived from Giardia intestinalis through Differential Centrifugation

open access: yesLife, 2023
Giardia intestinalis is a flagellated unicellular protozoan that colonizes the small intestine, causing the diarrheal disease called giardiasis. The production of extracellular vesicles (EVs) by G. intestinalis and the role of these EVs in the parasite’s
Abel Sana   +5 more
doaj   +1 more source

Extracellular Vesicles in neural cell interaction and CNS homeostasis

open access: yesFASEB BioAdvances, 2021
Central nervous system (CNS) homeostasis critically depends on the interaction between neurons and glia cells. Extracellular vesicles (EVs) recently emerged as versatile messengers in CNS cell communication.
Andrea Schnatz   +3 more
doaj   +1 more source

Bacterial subversion of NLR-mediated immune responses

open access: yesFrontiers in Immunology, 2022
Members of the mammalian Nod-like receptor (NLR) protein family are important intracellular sensors for bacteria. Bacteria have evolved under the pressure of detection by host immune sensing systems, leading to adaptive subversion strategies to dampen ...
Ioannis Kienes   +7 more
doaj   +1 more source

Lipid-Based Nanosystems for the Topical Application of Ferulic Acid: A Comparative Study

open access: yesPharmaceutics, 2023
In this study, we examined and compared two different lipid-based nanosystems (LBNs), namely Transferosomes (TFs) and Monoolein Aqueous Dispersions (MADs), as delivery systems for the topical application of Ferulic Acid (FA), an antioxidant molecule ...
Maddalena Sguizzato   +7 more
doaj   +1 more source

Data Analysis and Background Subtraction in Neutron Spin Echo Spectroscopy

open access: yesFrontiers in Physics, 2021
With the constantly improving performance of neutron spin echo (NSE) spectrometers it becomes possible to perform measurements on increasingly complex samples and to study more and more delicate effects.
Ingo Hoffmann
doaj   +1 more source

Chitosan Soft Matter Vesicles Loaded with Acetaminophen as Promising Systems for Modified Drug Release

open access: yesMolecules, 2023
Our study was designed to acquire, characterize and evaluate the biocompatibility of novel lipid vesicles loaded with acetaminophen (APAP) and coated with chitosan (CS).
Loredana Nicoleta Hilițanu   +8 more
doaj   +1 more source

Lidosomes: Innovative Vesicular Systems Prepared from Lidocaine Surfadrug

open access: yesPharmaceutics, 2022
Lidocaine is a local anaesthetic drug with an amphiphilic structure able to self-associate, under certain conditions, in molecular aggregates playing the role of both carrier and drug.
Martina Romeo   +3 more
doaj   +1 more source

Cutaneous manifestations of coronavirus disease in Turkey: A prospective study

open access: yesDermatologica Sinica, 2021
Background: Although the clinical features of coronavirus disease 2019 (COVID-19) infection are mainly based on respiratory system symptoms, different types of skin manifestations have been described in the literature.
Yeniay Yildiray, Pekdemir Sen Ayse
doaj   +1 more source

An improved assay to measure the phospholipid transfer activity of microsomal triglyceride transport protein

open access: yesJournal of Lipid Research, 2021
Microsomal triglyceride transfer protein (MTP) is essential for the assembly and secretion of apolipoprotein B-containing lipoproteins. MTP transfers diverse lipids such as triacylglycerol (TAG) and phospholipids (PLs) between vesicles in vitro ...
Narasimha Anaganti   +2 more
doaj   +1 more source

Ionically Crosslinked Complex Gels Loaded with Oleic Acid-Containing Vesicles for Transdermal Drug Delivery

open access: yesPharmaceutics, 2020
Skin is an attractive site for drug administration partly because of its easy accessibility and favorable properties (e.g., less invasiveness and high patient compliance) over some other common routes of administration.
Wing-Fu Lai, Ryan Tang, Wing-Tak Wong
doaj   +1 more source

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