Results 131 to 140 of about 9,455 (159)

Loss of Striatal Vesicular Monoamine Transporter Protein (VMAT2) in Human Cocaine Users

American Journal of Psychiatry, 2003
The hypothesis that human cocaine users lose vesicular monoamine transporter (VMAT2) protein was tested in striatal samples from cocaine users and age-, sex-, and postmortem interval-matched comparison subjects.Striatal samples were retrieved at autopsy; immunoblot assays were then performed by using a highly specific VMAT2 antibody.
Karley Y, Little, David M, Krolewski, Lian, Zhang, Bader J, Cassin   +3 more
openaire   +2 more sources

Protein Kinase A Affects Trafficking of the Vesicular Monoamine Transporters in PC12 Cells

Traffic, 2004
Previous studies have shown that the vesicular monoamine transporter 2 (VMAT2) is localized to both large dense core vesicles and synaptic vesicles in vivo. However, when exogenously expressed in PC12 cells, VMAT2 localizes only to large dense core vesicles. This distribution is similar to that of the endogenous vesicular monoamine transporter 1 (VMAT1)
Jia, Yao, Jeffrey D, Erickson, Louis B, Hersh   +2 more
openaire   +2 more sources

Vesicular monoamine transporter-1 (VMAT-1) mRNA and immunoreactive proteins in mouse brain.

Neuro endocrinology letters, 2011
Vesicular monoamine transporter 1 (VMAT-1) mRNA and protein were examined (1) to determine whether adult mouse brain expresses full-length VMAT-1 mRNA that can be translated to functional transporter protein and (2) to compare immunoreactive VMAT-1 proteins in brain and adrenal.VMAT-1 mRNA was detected in mouse brain with RT-PCR. The cDNA was sequenced,
Karen M, Ashe, Wan-Ling, Chiu, Ahmed M, Khalifa, Antoine N, Nicolas, Bonnie L, Brown, Randall R, De Martino, Clayton P, Alexander, Christopher T, Waggener, Krista, Fischer-Stenger, Jennifer K, Stewart   +9 more
openaire   +2 more sources

Vesicular monoamine transporter protein expression in neuroblastoma: A report from the Children’s Oncology Group.

Journal of Clinical Oncology, 2015
10043 Background: Vesicular monoamine transporters 1 and 2 (VMAT1 and VMAT2) are thought to mediate MIBG uptake in adult neuroendocrine tumors.
Steven G. DuBois, William Temple, Lori Mendelsohn, Grace E. Kim, Erin Nekritz, Clay Gustafson, Lawrence Lin, Kathy Giacomini, Arlene Naranjo, Collin Van Ryn, Gregory A Yanik, Susan G. Kreissman, Michael D. Hogarty, Katherine K. Matthay   +13 more
openaire   +1 more source

Structural organization of the human vesicular monoamine transporter type-2 gene and promoter analysis using the jelly fish green fluorescent protein as a reporter

Molecular Brain Research, 1997
The genomic structure of a human vesicle monoamine transporter, type-2 (hVMAT2) was determined from two overlapping cosmids, phVMAT2-cos1 and phVMT2-cos2, spanning more than 35 kb. The hVMAT2 open reading frame is encoded by 16 exons, with translation initiation and termination in exon 2 and exon 16, respectively.
W, Xu, L, Liu, K, Mooslehner, P C, Emson
openaire   +2 more sources

MUTATION OF THE VESICULAR MONOAMINE TRANSPORTER-1 GENE ALTERS ITS PROTEIN PRODUCT

2010
VCU Theses and ...
openaire   +1 more source

Regulation of Vesicular Monoamine and Glutamate Transporters by Vesicle-Associated Trimeric G Proteins: New Jobs for Long-Known Signal Transduction Molecules

2006
Neurotransmitters of neurons and neuroendocrine cells are concentrated first in the cytosol and then in either small synaptic vesicles ofpresynaptic terminals or in secretory vesicles by the activity of specific transporters of the plasma and the vesicular membrane, respectively.
I, Brunk, M, Höltje, B, von Jagow, S, Winter, J, Sternberg, C, Blex, I, Pahner, G, Ahnert-Hilger   +7 more
openaire   +2 more sources

Expression of vesicular monoamine transporters, synaptosomal-associated protein 25 and syntaxin1: a signature of human small cell lung carcinoma.

Cancer research, 2001
Vesicular monoamine transporters (VMATs) are a prerequisite for the uptake of biogenic amines into intracellular storage organelles, whereas soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs; such as SNAP-25 and syntaxin1) are essential for exocytosis of biogenic amines by neurons and endocrine cells.
L, Graff, F, Castrop, M, Bauer, H, Höfler, M, Gratzl   +4 more
openaire   +1 more source

425. Cocaine effects on striatal dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) protein in humans

Biological Psychiatry, 2000
S. Oakman, L. Zhang, R. Maddox, K.Y. Little   +3 more
openaire   +1 more source

SNX5 targets a monoamine transporter to the TGN for assembly into dense core vesicles by AP-3

Journal of Cell Biology, 2022
Hongfei Xu, Robert H Edwards
exaly