Results 91 to 100 of about 149,274 (318)

Optimized ACE2‐Fc fusion proteins with picomolar neutralization activity against highly evolved SARS‐CoV‐2 variants

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract The rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has compromised the efficacy of many authorized monoclonal antibody products. This highlights the need for alternative strategies, especially for vulnerable populations such as immunocompromised individuals.
Ferran Abancó   +16 more
wiley   +1 more source

Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Shriya Makam, Hana M. Dobrovolny
wiley   +1 more source

Safety of Recombinant VSV–Ebola Virus Vaccine Vector in Pigs

open access: yesEmerging Infectious Diseases, 2015
The ongoing Ebola outbreak in West Africa has resulted in fast-track development of vaccine candidates. We tested a vesicular stomatitis virus vector expressing Ebola virus glycoprotein for safety in pigs.
Emmie de Wit   +7 more
doaj   +1 more source

Molecular Screening of Black Flies (Diptera: Simuliidae) for Vector‐Borne Zoonotic Pathogens, South Moravia, Czech Republic

open access: yesZoonoses and Public Health, Volume 73, Issue 1, Page 95-106, February 2026.
ABSTRACT Introduction Black flies (Simuliidae) are globally distributed blood‐feeding arthropods and vectors of viral, bacterial, and parasitic pathogens to many animal species, including humans. We investigated the occurrence of selected vector‐borne pathogens in black flies in South Moravia, Czech Republic, and evaluated their possible role in the ...
Silvie Šikutová   +10 more
wiley   +1 more source

RISK OF INTRODUCING HIGHLY DANGEROUS ANIMAL VESICULAR DISEASES INTO THE RUSSIAN FEDERATION

open access: yesВетеринария сегодня, 2019
Animal vesicular diseases are rather widespread in the world. Transboundary vesicular diseases are mainly registered in African and Asian countries. They primarily include foot and mouth disease, sheep and goat pox, peste des petits ruminants, lumpy skin
V. P. Semakina   +3 more
doaj   +1 more source

Differentiation of Foot-and-Mouth Disease-Infected pigs from Vaccinated Pigs Using Antibody-Detecting Sandwich ELISA [PDF]

open access: yes, 2011
The presence of serum antibodies for nonstructural proteins of the foot-and-mouth disease virus (FMDV) can differentiate FMDV-infected animals from vaccinated animals.
Aldo DEKKER   +10 more
core   +3 more sources

Bee products as alternatives in the treatment of viral infections

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 1, Page 33-54, 15 January 2026.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba   +3 more
wiley   +1 more source

Full Genomic Sequencing of Vesicular Stomatitis Virus Isolates from the 2004–2006 US Outbreaks Reveals Associations of Viral Genetics to Environmental Variables

open access: yesProceedings, 2020
Vesicular stomatitis (VS) outbreaks in the western USA occur cyclically, approximately every 8–10 years. Phylogenetic evidence based on a 450 nt region of the P coding sequences suggests that the initial introduction was a single viral lineage closely ...
Rachel Palinski   +7 more
doaj   +1 more source

Selection of single-chain antibodies that specifically interact with vesicular stomatitis virus (VSV) nucleocapsid and inhibit viral RNA synthesis. [PDF]

open access: yes, 2005
International audienceThe RNA genome of non-segmented negative-strand RNA viruses is completely covered by the nucleoprotein (N) forming a ribonucleoprotein complex, the nucleocapsid.
Cortay, Jean-Claude   +2 more
core   +3 more sources

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

open access: yesFEBS Open Bio, Volume 16, Issue 1, Page 41-51, January 2026.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

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