Results 91 to 100 of about 146,054 (301)

Evaluating Temperature Sensitivity of Vesicular Stomatitis Virus–Based Vaccines

Emerging Infectious Diseases, 2019
Use of the vesicular stomatitis virus (VSV)–based Ebola virus vaccine during outbreaks and the potential use of a similar VSV-based Lassa virus vaccine has raised questions about the vaccines’ stability should the cold chain fail.
Derek R. Stein, Patrycja Sroga, Bryce M. Warner, Yvon Deschambault, Guillaume Poliquin, David Safronetz   +5 more
doaj   +1 more source

Neurotropism of Vesicular Stomatitis Virus

Experimental Biology and Medicine, 1933
The virus of vesicular stomatitis is peculiarly epitheliotropic (der-motropic) in the guinea pig: only the pad tissue of the dermal surface is uniformly susceptible.1, 2, 3Through the kindness of Dr. W. E. Cotton, samples were sent us of Indiana and New Jersey strains of virus propagated in guinea pig pads for several years.
Herald R. Cox, Peter K. Olitsky
openaire   +2 more sources

Vesicular Stomatitis Virus: Mode of Transcription

Journal of General Virology, 1977
Recent studies on the mechanism by which the virion-associated RNA polymerase of vesicular stomatitis virus transcribes RNA have revealed several new biological features of general interest. The mode of synthesis of the 5'-terminal cap structure of the mRNAs, the sequential transcription of the genes and the presence of a transcribed "leader" RNA ...
R. J. Colonno, G. Abraham, Amiya K. Banerjee   +2 more
openaire   +3 more sources

Structural Proteins of Vesicular Stomatitis Viruses [PDF]

Journal of Virology, 1969
Three major and three minor structural proteins were identified by polyacrylamide gel electrophoresis of purified infectious virions of the Indiana serotype of vesicular stomatitis (VS) virus disrupted with acetic acid, 0.5 m urea, sodium dodecyl sulfate (SDS), and 2-mercaptoethanol.
Terry A. Schnaitman, Robert R. Wagner, Ruth M. Snyder   +2 more
openaire   +3 more sources

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

Vesicular stomatitis virus G glycoprotein pseudotyped retroviral vectors: concentration to very high titer and efficient gene transfer into mammalian and nonmammalian cells.

Proceedings of the National Academy of Sciences of the United States of America, 1993
The restricted host-cell range and low titer of retroviral vectors limit their use for stable gene transfer in eukaryotic cells. To overcome these limitations, we have produced murine leukemia virus-derived vectors in which the retroviral envelope ...
J. Burns, T. Friedmann, W. Driever, M. Burrascano, J. Yee   +4 more
semanticscholar   +1 more source

Ultrafiltration of the Virus of Vesicular Stomatitis

Experimental Biology and Medicine, 1935
SummaryThe filtration end-point of the virus of vesicular stomatitis, or the average pore diameter of the finest membrane passing the virus, was found to be approximately 140 mμ. Two im-munologically distinct strains of the virus, the “Indiana” and the “New Jersey” maintained either in tissue culture or in mouse brain, were studied, and the filtration ...
Johannes H. Bauer, Herald E. Cox
openaire   +2 more sources

Advanced Imaging and Cytometric Techniques to Characterize Lipid Accumulation in Wolman Disease

Cytometry Part A, EarlyView.
ABSTRACT Wolman disease (WD) is a severe lysosomal storage disorder characterized by fatal lipid accumulation caused by the deficiency of a lipid metabolic enzyme, Lysosomal Acid Lipase (LAL), involved in the lysosomal hydrolysis of cholesterols and triglycerides.
Marine Laurent, Jérémie Cosette, Giulia Pavani, Sarah Bayol, Christine Jenny, Rim Harb, Julie Oustelandt, Anais Brassier, Daniel Stockholm, Mario Amendola   +9 more
wiley   +1 more source

Postexposure Treatment of Marburg Virus Infection

Emerging Infectious Diseases, 2010
Rhesus monkeys are protected from disease when a recombinant vesicular stomatitis virus–based vaccine is administered 20–30 min after infection with Marburg virus.
Thomas W. Geisbert, Lisa E. Hensley, Joan B. Geisbert, Anders Leung, Joshua C. Johnson, Allen Grolla, Heinz Feldmann   +6 more
doaj   +1 more source

Bee products as alternatives in the treatment of viral infections

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba, Łukasz Marek, Jerzy Stojko, Anna Rzepecka‐Stojko   +3 more
wiley   +1 more source