Results 21 to 30 of about 24,925 (205)

Phenotypic lentivirus screens to identify functional single domain antibodies [PDF]

, 2016
Manipulation of proteins is key in assessing their in vivo function. Although genetic ablation is straightforward, reversible and specific perturbation of protein function remains a challenge.
Brewer, Rebeccah, Brusic, Vesna, Hanke, Leo, Morin, Benjamin, Ploegh, Hidde, Schmidt, Florian I., Whelan, Sean P.J.   +6 more
core   +2 more sources

Comparative analysis of oncolytic potential of vesicular stomatitis virus serotypes Indiana and New Jersey in cancer cell lines

Сеченовский вестник, 2023
Aim. Compare the lytic efficiency and the kinetics of accumulation of vesicular stomatitis virus serotypes Indiana (VSV-IND) and New Jersey (VSV-NJ) on cell lines of mouse melanoma B16F10, human hepatocellular carcinoma HepG2 and human mammary ...
A. S. Isaeva, N. O. Porozova, E. Idota, S. I. Volodina, A. N. Lukashev, A. S. Malogolovkin   +5 more
doaj   +1 more source

Cytokine-modified VSV is attenuated for neural pathology, but is both highly immunogenic and oncolytic [PDF]

, 2009
Vesicular stomatitis virus (VSV), an enveloped, nonsegmented, negative-stranded RNA virus, is being tested by several laboratories as an antitumor agent.
Bidula, Sarah M, Jensen, Troels M, Miller, James, Reiss, Carol Shoshkes   +3 more
core   +1 more source

First case report of vesicular stomatitis in the State of Paraíba, Brazil

Semina: Ciências Agrárias, 2014
The present report describes the first case of vesicular stomatitis in the State of Paraíba, Brazil. Records from the Official Veterinary Services of the State of Paraíba were analyzed while responding to a suspected case of vesicular disease at a ...
Inácio José Clementino , Janete Okamoto Lima , Daniella Godoy Coutinho , Ericka Rejane Correia de Albuquerque , Albério Antônio de Barros Gomes , Sérgio Santos de Azevedo   +5 more
doaj   +1 more source

Single Nucleotide Variants of the Human TIM-1 IgV Domain with Reduced Ability to Promote Viral Entry into Cells

Viruses, 2022
Human T-cell immunoglobulin mucin 1 (hTIM-1) is known to promote cellular entry of enveloped viruses. Previous studies suggested that the polymorphisms of hTIM-1 affected its function.
Takanari Hattori, Takeshi Saito, Hiroko Miyamoto, Masahiro Kajihara, Manabu Igarashi, Ayato Takada   +5 more
doaj   +1 more source

Modified Alphavirus-Vesiculovirus Hybrid Vaccine Vectors for Homologous Prime-Boost Immunotherapy of Chronic Hepatitis B

Vaccines, 2020
Virus-like vesicles (VLV) are hybrid vectors based on an evolved Semliki Forest virus (SFV) RNA replicon and the envelope glycoprotein (G) from vesicular stomatitis virus (VSV).
Carolina Chiale, Timur O. Yarovinsky, Stephen W. Mason, Bhaskara R. Madina, Manisha Menon, Marie M. Krady, Safiehkhatoon Moshkani, Anasuya Chattopadhyay Pal, Bijan Almassian, John K. Rose, Michael D. Robek, Valerian Nakaar   +11 more
doaj   +1 more source

Transcriptome dataset of six human pathogen RNA viruses generated by nanopore sequencing

Data in Brief, 2022
Long-read sequencing (LRS) approaches shed new light on the complexity of viral (Kakuk et al., 2021 [1]; Boldogkői et al., 2019 [2]; Depledge et a., 2019 [3]), bacterial (Yan et al., 2018 [4]) and eukaryotic (Tilgner et al., 2014 [5]) transcriptomes ...
István Prazsák, Zsolt Csabai, Gábor Torma, Henrietta Papp, Fanni Földes, Gábor Kemenesi, Ferenc Jakab, Gábor Gulyás, Ádám Fülöp, Klára Megyeri, Béla Dénes, Zsolt Boldogkői, Dóra Tombácz   +12 more
doaj   +1 more source

Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma [PDF]

, 2010
A fully intact immune system would be expected to hinder the efficacy of oncolytic virotherapy by inhibiting viral replication. Simultaneously, however, it may also enhance antitumor therapy through initiation of proinflammatory, antiviral cytokine ...
Barber, G, Diaz, RM, Galivo, F, Kottke, T, Melcher, A, Thompson, J, Vile, R, Wongthida, P   +7 more
core   +1 more source

Malpais spring virus is a new species in the genus vesiculovirus [PDF]

, 2013
BACKGROUND: Malpais Spring virus (MSPV) is a mosquito-borne rhabdovirus that infects a variety of wild and feral ungulates in New Mexico, including horses and deer. Although, initial serologic tests and electron microscopy at the time of isolation nearly
Amelia PA Travassos da Rosa, Edward C Holmes, Nikos Vasilakis, Peter J Walker, Robert B Tesh, Steven Widen, Thomas G Wood   +6 more
core   +1 more source

USE OF REAL-TIME qRT-PCR FOR FMD VIRUS DETECTION IN CATTLE MILK

Ветеринария сегодня, 2019
FMDV can be shed with milk of infected animals and infect susceptible animals. The possibility of using real-time qRT-PCR for FMD virus detection in cattle milk was assessed. To prepare samples of FMDV infected milk the following strains were used: А No.
A. M. Timina, S. N. Fomina, Т. К. Mayorova   +2 more
doaj   +1 more source