Results 91 to 100 of about 83,240 (318)
Transsynaptic Tracing with Vesicular Stomatitis Virus Reveals Novel Retinal Circuitry
The use of neurotropic viruses as transsynaptic tracers was first described in the 1960s, but only recently have such viruses gained popularity as a method for labeling neural circuits.
Kevin T. Beier +5 more
semanticscholar +1 more source
A Novel Murine Model of Hemophagocytic Lymphohistiocytosis‐Like Inflammation in ZNFX1 Deficiency
LCMV‐infected Znfx1‐deficient mice develop hemophagocytic lymphohistiocytosis (HLH)‐like immune dysregulation, mirroring key aspects of the immunopathology observed in ZNFX1‐deficient patients. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a severe inflammatory syndrome characterized by persistent activation of lymphocytes and macrophages ...
Diana Tintor +9 more
wiley +1 more source
Immune evasion of the CD1d/NKT cell axis [PDF]
Many reviews on the CD1d/NKT cell axis focus on the ability of CD1d-restricted NKT cells to serve as effector cells in a variety of disorders, be they infectious diseases, cancer or autoimmunity.
Brutkiewicz, Randy R. +2 more
core +1 more source
Cultivation of Vesicular Stomatitis Virus
Carrel, Olitsky, and Long1 reported the successful cultivation of the virus of vesicular stomatitis of horses in 1928. In their cultivation experiments, guinea pig tissues were used throughout. The method they employed consisted in placing embryonic tissue or adult bone marrow in contact with the virus which had been suspended in Tyrode's solution for ...
Cox, H. R. +2 more
openaire +1 more source
Vesicular stomatitis virus as a flexible platform for oncolytic virotherapy against cancer.
Oncolytic virus (OV) therapy is an emerging anti-cancer approach that utilizes viruses to preferentially infect and kill cancer cells, while not harming healthy cells.
Eric Hastie, V. Grdzelishvili
semanticscholar +1 more source
This review explores nanoparticle (NP)‐based biosensors and nanovaccine platforms for arboviral infections, highlighting their design, performance, and translational potential. By comparing case studies across viruses, it identifies gold‐standard nanomaterials such as gold NPs (AuNPs), zinc oxide NPs (ZnONPs), molybdenum disulfide (MoS2) nanocomposites,
Peyman Halvaeikhanekahdani +3 more
wiley +1 more source
Differentiation of Foot-and-Mouth Disease-Infected pigs from Vaccinated Pigs Using Antibody-Detecting Sandwich ELISA [PDF]
The presence of serum antibodies for nonstructural proteins of the foot-and-mouth disease virus (FMDV) can differentiate FMDV-infected animals from vaccinated animals.
Aldo DEKKER +10 more
core +3 more sources
Vesicular stomatitis virus (VSV) represents an attractive oncolytic virotherapy platform because of its potent tumor cell-killing and immune-stimulating properties; yet the clinical translation of VSV faces numerous challenges, such as inefficient ...
Michael Karl Melzer +7 more
doaj +1 more source
Abstract The rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has compromised the efficacy of many authorized monoclonal antibody products. This highlights the need for alternative strategies, especially for vulnerable populations such as immunocompromised individuals.
Ferran Abancó +16 more
wiley +1 more source
Mathematical Modeling of the Role of Cytokines in Sindbis Virus Treatment of Glioblastoma
ABSTRACT Oncolytic viruses, specifically Sindbis virus (SINV), combined with cytokines show promising results in slowing glioma progression, but a quantitative understanding of their effects remains limited. In this study, we use an ordinary differential equation (ODE) model to examine the effect of adding cytokines to oncolytic SINV therapy.
Shriya Makam, Hana M. Dobrovolny
wiley +1 more source

