Results 111 to 120 of about 1,140,792 (221)

A Vesicular Stomatitis Virus Replicon-Based Bioassay for the Rapid and Sensitive Determination of Multi-Species Type I Interferon

PLoS ONE, 2011
Type I interferons (IFN) comprise a family of cytokines that signal through a common cellular receptor to induce a plethora of genes with antiviral and other activities. Recombinant IFNs are used for the treatment of hepatitis C virus infection, multiple
Marianne Berger Rentsch, G. Zimmer
semanticscholar   +1 more source

Ribonucleic Acid Synthesis of Vesicular Stomatitis Virus, II. An RNA Polymerase in the Virion [PDF]

, 1970
The virions of vesicular stomatitis virus contain an enzyme that catalyzes the incorporation of ribonucleotides into RNA. The product of the reaction is mainly RNA complementary in base sequence to that of vesicular stomatitis virus ...
Stampfer, Martha, Baltimore, David, Huang, Alice S.   +2 more
core  

Pseudotyping of vesicular stomatitis virus with the envelope glycoproteins of highly pathogenic avian influenza viruses

, 2014
Pseudotype viruses are useful for studying the envelope proteins of harmful viruses. This work describes the pseudotyping of vesicular stomatitis virus (VSV) with the envelope glycoproteins of highly pathogenic avian influenza viruses.
Zimmer, Gert, Halbherr, Stefan J, Berger Rentsch, Marianne, Locher, Samira   +3 more
core   +1 more source

Acute malaria dysregulates specialized lymph node macrophages to suppress vaccine-elicited protection against the Ebola virus

mBio
The filovirus, Ebola virus (EBOV), causes outbreaks of EBOV disease (EVD) throughout equatorial Africa. ERVEBO is a replication-competent recombinant vesicular stomatitis virus-vectored vaccine encoding the EBOV glycoprotein (recombinant vesicular ...
Jonah Elliff, Lindsey Grady, Kyle L. O'Donnell, Caitlin Messingham, Kai J. Rogers, Jobaida Akther, Andrew Thurman, Rahul Vijay, Alejandro Pezzulo, Troy Randall, Andrea Marzi, Noah S. Butler, Wendy Maury   +12 more
doaj   +1 more source

Interferon Response and Viral Evasion by Members of the Family Rhabdoviridae

Viruses, 2009
Like many animal viruses, those of the Rhabdoviridae family, are able to antagonize the type I interferon response and cause disease in mammalian hosts. Though these negative-stranded RNA viruses are very simple and code for as few as five proteins, they
Matthias J. Schnell, Elizabeth J. Faul, Douglas S. Lyles   +2 more
doaj   +1 more source

Structure of the Vesicular Stomatitis Virus N0-P Complex

PLoS Pathogens, 2011
Replication of non-segmented negative-strand RNA viruses requires the continuous supply of the nucleoprotein (N) in the form of a complex with the phosphoprotein (P).
C. Leyrat, F. Yabukarski, N. Tarbouriech, E. Ribeiro, M. R. Jensen, M. Blackledge, R. Ruigrok, M. Jamin   +7 more
semanticscholar   +1 more source

The structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex reveals the protein-membrane and lateral protein-protein interaction [PDF]

, 2013
Glycoprotein B (gB) is a key component of the complex herpesvirus fusion machinery. We studied membrane interaction of two gB ectodomain forms and present an electron cryotomography structure of the gB-bilayer complex.
Topf, Maya, Huiskonen, JT, Topf, M., Maurer, U., Whitbeck, J., Maurer, U.E., Gruenewald, Kay, Cohen, G., Cairns, T.M., Eisenberg, R.J., Huiskonen, Juha T., Whitbeck, J.C., Zeev-Ben-Mordehai, T, Cohen, Gary H., Cohen, GH, Cairns, Tina M., Hannah, BP, Hannah, B.P., Cohen, G.H., Pandurangan, A., Zeev-Ben-Mordehai, T., Grünewald, K, Eisenberg, Roselyn J., Cairns, T., Huiskonen, J.T., Maurer, Ulrike E., Grünewald, Kay, Eisenberg, RJ, Topf, M, Grünewald, K., Maurer, UE, Pandurangan, Arun Prasad, Whitbeck, JC, Zeev-Ben-Mordehai, Tzviya, Huiskonen, J., Hannah, Brian P., Hannah, B., Pandurangan, Arun, Pandurangan, AP, Eisenberg, R., Whitbeck, J. Charles, Cairns, TM   +41 more
core   +2 more sources

Vesicular stomatitis virus as a treatment for colorectal cancer

Cancer Gene Therapy, 2011
M protein mutant vesicular stomatitis virus is an attractive candidate oncolytic virus for the treatment of metastatic colorectal cancer due to its ability to kill cancer cells that are defective in their antiviral responses.
J. Stewart, Maryam Ahmed, S. Northrup, M. Willingham, D. Lyles   +4 more
semanticscholar   +1 more source

Autographa californica Multicapsid Nucleopolyhedrovirus efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH [PDF]

, 2010
The budded virus (BV) of the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) infects insect cells and transduces mammalian cells mainly through the endocytosis pathway.
F. Deng, M. Wang, Dong, S., Vlak, J.M., Deng, F., S. Dong, Wang, M., Qiu, Z., Z. Hu, Hu, Z.H., J. M. Vlak, H. Wang, Z. Qiu, Wang, H.L.   +13 more
core   +1 more source

Fewer protective cytotoxic T-cell epitopes than T-helper-cell epitopes on vesicular stomatitis virus.

, 1993
Cytotoxic T-lymphocyte (CTL) and T-helper-cell responses in various mouse strains were monitored. Protective CTL responsiveness against three proteins of vesicular stomatitis virus was H-2 linked and inducible only in half of the 15 combinations tested ...
Castelmur, I, Binder, D, Zinkernagel, RM, Abraham, D, Hengartner, H, Bachmann, MF, Kündig, TM   +6 more
core   +2 more sources