Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P+3 more
core +1 more source
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has threatened human health and the global economy. Development of additional vaccines and therapeutics is urgently required, but such development with live virus must be ...
Yoichiro Fujioka+7 more
doaj +1 more source
Revisam-se as doenças que devem ser consideradas no diagnóstico diferencial de febre aftosa. Dentre as doenças vesiculares ou erosivas, descrevem-se os principais aspectos relacionados ao diagnóstico da estomatite vesicular, diarréia viral bovina, febre ...
Franklin Riet-Correa+3 more
doaj +1 more source
The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials
The devastating Ebola virus (EBOV) epidemic in West Africa in 2013–2016 accelerated the progress of several vaccines and antivirals through clinical trials, including the replication-competent vesicular stomatitis virus-based vaccine expressing the EBOV ...
Ellen L. Suder+4 more
semanticscholar +1 more source
Autophagy gene activity may act as a key factor for sensitivity of tumor cells to oncolytic vesicular stomatitis virus [PDF]
Background: Beclin1 is an important, primary molecule for autophagy. Objectives: It is suggested that the control of the autophagy path increases the sensitivity of tumor cells to VSV.
Arefian, E.+3 more
core +2 more sources
Bat Employs a Conserved MDA5 Gene to Trigger Antiviral Innate Immune Responses
Bats are important hosts for various zoonotic viral diseases. However, they rarely show signs of disease infection with such viruses. As the first line for virus control, the innate immune system of bats attracted our full attention.
Jie Wang+9 more
doaj +1 more source
Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor
The large (L) proteins of non-segmented, negative-strand RNA viruses are multifunctional enzymes that produce capped, methylated and polyadenylated mRNAs and replicate the viral genome.
S. Jenni+6 more
semanticscholar +1 more source
Recombinant vesicular stomatitis virus vector vaccines for WHO blueprint priority pathogens
The devastating Ebola virus (EBOV) outbreak in West Africa in 2013–2016 has flagged the need for the timely development of vaccines for high-threat pathogens. To be better prepared for new epidemics, the WHO has compiled a list of priority pathogens that
Anahita Fathi, C. Dahlke, M. Addo
semanticscholar +1 more source
Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes [PDF]
Synthetic phospholipid vesicles (liposomes) containing the purified glycoprotein (G) of vesicular stomatitis virus (VSV) and solubilized membrane proteins from cells of the appropriate H-2 haplotype elicited H-2-restricted cytotoxic T lymphocytes (CTL ...
Baltimore, David+4 more
core +1 more source
Cultivation of Vesicular Stomatitis Virus
Carrel, Olitsky, and Long1 reported the successful cultivation of the virus of vesicular stomatitis of horses in 1928. In their cultivation experiments, guinea pig tissues were used throughout. The method they employed consisted in placing embryonic tissue or adult bone marrow in contact with the virus which had been suspended in Tyrode's solution for ...
Jerome T. Syverton+2 more
openaire +2 more sources