Results 61 to 70 of about 80,112 (305)
Neurotropism of Vesicular Stomatitis Virus
The virus of vesicular stomatitis is peculiarly epitheliotropic (der-motropic) in the guinea pig: only the pad tissue of the dermal surface is uniformly susceptible.1, 2, 3Through the kindness of Dr. W. E. Cotton, samples were sent us of Indiana and New Jersey strains of virus propagated in guinea pig pads for several years.
Herald R. Cox, Peter K. Olitsky
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Vesicular Stomatitis Virus: Mode of Transcription
Recent studies on the mechanism by which the virion-associated RNA polymerase of vesicular stomatitis virus transcribes RNA have revealed several new biological features of general interest. The mode of synthesis of the 5'-terminal cap structure of the mRNAs, the sequential transcription of the genes and the presence of a transcribed "leader" RNA ...
R. J. Colonno+2 more
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Ultrafiltration of the Virus of Vesicular Stomatitis
SummaryThe filtration end-point of the virus of vesicular stomatitis, or the average pore diameter of the finest membrane passing the virus, was found to be approximately 140 mμ. Two im-munologically distinct strains of the virus, the “Indiana” and the “New Jersey” maintained either in tissue culture or in mouse brain, were studied, and the filtration ...
Johannes H. Bauer, Herald E. Cox
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Measuring Genetic Robustness in Vesicular Stomatitis Virus
Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes. Thus, more robust viruses have an increased neutral mutation rate.
Isabel Novella
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Recent reports have revealed that oncolytic viruses (OVs) play a significant role in cancer therapy. The infection of OVs such as oncolytic vaccinia virus (OVV), vesicular stomatitis virus (VSV), parvovirus, mammalian reovirus (MRV), human adenovirus ...
Yi-Ying Wu+9 more
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Proteins of Vesicular Stomatitis Virus and of Phenotypically Mixed Vesicular Stomatitis Virus-Simian Virus 5 Virions [PDF]
The identity of the glycoprotein of vesicular stomatitis virus (VSV) as the spike protein has been confirmed by the removal of the spikes with a protease from Streptomyces griseus , leaving bullet-shaped particles bounded by a smooth membrane.
Purnell W. Choppin+2 more
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Epitaxial piezoelectric α‐quartz/Si BioNEMS sensors, made using soft chemistry, effectively detect the Chikungunya virus. They have a mass sensitivity of 205 pg Hz−1 in liquid and can detect the virus at a limit of 9 ng mL−1. This development enables high‐frequency mass devices for point‐of‐care testing in healthcare and other electronic applications ...
Raissa Rathar+12 more
wiley +1 more source
Cytokine-modified VSV is attenuated for neural pathology, but is both highly immunogenic and oncolytic [PDF]
Vesicular stomatitis virus (VSV), an enveloped, nonsegmented, negative-stranded RNA virus, is being tested by several laboratories as an antitumor agent.
Bidula, Sarah M+3 more
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The restricted host-cell range and low titer of retroviral vectors limit their use for stable gene transfer in eukaryotic cells. To overcome these limitations, we have produced murine leukemia virus-derived vectors in which the retroviral envelope ...
J. Burns+4 more
semanticscholar +1 more source
Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu+13 more
wiley +1 more source