A CRISPR activation screen identifies CH25H as a restriction factor against influenza viruses by targeting accessible cholesterol. [PDF]
Huang J +15 more
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Cargo-driven extracellular vesicles as pharmaceutical nanocarriers: A pharmaceutics-oriented comparison of animal exosomes and plant-derived exosome-like nanoparticles. [PDF]
Xu H, Zhang J, Li M.
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TPC2 regulates proteomic remodeling, bioenergetic phenotypes, and mitochondrial stress adaptation in melanoma. [PDF]
As Sobeai HM +10 more
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A Highly Conserved SNARE-Associated Protein Enhances Plant Immunity by Regulating Vesicle Trafficking. [PDF]
Hawk TE +15 more
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ELAPOR1 regulates VPS54-mediated GARP complex formation and proacrosomal vesicle fusion during spermatogenesis. [PDF]
Ding C +13 more
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THE ROLE OF VESICULAR TRANSPORT PROTEINS IN SYNAPTIC TRANSMISSION AND NEURAL DEGENERATION
Annual Review of Neuroscience, 1997▪ Abstract Classical neurotransmitters are synthesized in the cytoplasm, so they require transport into secretory vesicles for regulated exocytotic release. Previous work has identified distinct vesicular transport activities for the different classical transmitters, and all depend on the H+-electrochemical gradient across the vesicle membrane but ...
R H Edwards
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Non-vesicular lipid transport by lipid-transfer proteins and beyond
Nature Reviews Molecular Cell Biology, 2010The movement of lipids within and between intracellular membranes is mediated by different lipid transport mechanisms and is crucial for maintaining the identities of different cellular organelles. Non-vesicular lipid transport has a crucial role in intracellular lipid trafficking and distribution, but its underlying mechanisms remain unclear.
Sima Lev
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Small GTP-binding proteins in vesicular transport
Trends in Biochemical Sciences, 1990Recent recognition of the abundance of small GTP-binding proteins in eukaryotic cells has sparked off a search for the possible function of these proteins. Evidence is accumulating that SAR1, ARF, SEC4 and YPT1 in yeast and the rab and arf family in mammalian cells play a central role in the regulation of vesicle transport and organelle function.
William E Balch
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Proteins involved in vesicular transport and membrane fusion
Current Opinion in Cell Biology, 1991In the past year, new information about proteins involved in vesicular transport has been plentiful. Particularly noteworthy are the complementary findings that Sec17p is required for vesicle consumption in endoplasmic reticulum-to-Golgi transport in yeast and that an analogous activity in mammalian cells, termed SNAP, is required for transport from ...
M Gérard Waters, J E Rothman
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The plant vesicular transport engineering for production of useful recombinant proteins
Journal of Molecular Catalysis B: Enzymatic, 2004Abstract The molecular breeding of plants that have been genetically engineered for improved disease resistance and stress tolerance has been undertaken with the goal of improving food production. More recently, it has been realized that transgenic plants can serve as bioreactors for the production of proteins or compounds with industrial or clinical
Takeshi Matsui, Atsuhiko Shinmyo
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