Results 1 to 10 of about 2,099 (169)
Lentivector Producer Cell Lines with Stably Expressed Vesiculovirus Envelopes [PDF]
Molecular Therapy - Methods & Clinical Development, 2018 Retroviral and lentiviral vectors often use the envelope G protein from the vesicular stomatitis virus Indiana strain (VSVind.G). However, lentivector producer cell lines that stably express VSVind.G have not been reported, presumably because of its cytotoxicity, preventing simple scale-up of vector production.
Mary Collins +17 more
doaj +12 more sources
Phylodynamics of Alagoas vesiculovirus in Brazil [PDF]
Brazilian Journal of Microbiology, 2022 The vesicular stomatitis virus belongs to the Rhabdoviridae family, genus Vesiculovirus. Four species (New Jersey, Indiana, Cocal, and Alagoas) are responsible for disease outbreaks in Western Hemisphere countries. In Brazil, the Alagoas virus is responsible for the main outbreaks of the disease, mainly in the states of the Northeast, Midwest, and ...
Antônio Augusto, Fonseca Júnior +6 more
europepmc +6 more sources
Multi-modal efficacy of a chimeric vesiculovirus expressing the Morreton glycoprotein in sarcoma [PDF]
Molecular Therapy - Oncolytics, 2022 AbstractVesiculoviruses are attractive oncolytic virus (OV) platforms due to their rapid replication, genome with appreciable transgene capacity, broad tropism, limited pre-existing immunity, and type I interferon response gradient between malignant and normal cells.
Chelsae R. Watters +12 more
europepmc +8 more sources
Outbreaks of Vesicular Stomatitis in Brazil caused by a distinct lineage of Alagoas vesiculovirus [PDF]
Brazilian Journal of Microbiology, 2021 This article describes the recurrence of outbreaks of Vesicular Stomatitis in the State of Maranhão, Brazil. The procedures for treating the outbreak of vesicular disease, sample collection, laboratory tests performed, and the results obtained were described. The clinical signs and observed injuries have been described.
Marcelo Fernandes Camargos +6 more
europepmc +7 more sources
Leader RNA regulates snakehead vesiculovirus replication via interacting with viral nucleoprotein [PDF]
RNA Biology, 2020 Leader RNA, a kind of virus-derived small noncoding RNA, has been proposed to play an important role in regulating virus replication, but the underlying mechanism remains elusive. In this study, snakehead vesiculovirus (SHVV), a kind of fish rhabdovirus causing high mortality to the cultured snakehead fish in China, was used to unveil the molecular ...
Xiangmou Qin +6 more
semanticscholar +6 more sources
Reviewing Chandipura: A Vesiculovirus in Human Epidemics [PDF]
Bioscience Reports, 2007 Chandipura virus, a member of the rhabdoviridae family and vesiculovirus genera, has recently emerged as human pathogen that is associated with a number of outbreaks in different parts of India. Although, the virus closely resembles with the prototype vesiculovirus, Vesicular Stomatitis Virus, it could be readily distinguished by its ability to infect ...
Arindam Mondal +4 more
openaire +4 more sources
Structural intermediates in the fusion‐associated transition of vesiculovirus glycoprotein [PDF]
The EMBO Journal, 2017 Vesiculoviruses enter cells by membrane fusion, driven by a large, low-pH-induced, conformational change in the fusion glycoprotein G that involves transition from a trimeric pre-fusion toward a trimeric post-fusion state via monomeric intermediates.
Eduard Baquero +10 more
openaire +7 more sources
Malpais spring virus is a new species in the genus vesiculovirus [PDF]
Virology Journal, 2013 Malpais Spring virus (MSPV) is a mosquito-borne rhabdovirus that infects a variety of wild and feral ungulates in New Mexico, including horses and deer. Although, initial serologic tests and electron microscopy at the time of isolation nearly 25 years ago provided evidence that MSPV is a novel virus, possibly related to vesiculoviruses, the virus still
Nikos Vasilakis +7 more
openaire +4 more sources
Susceptibility of various animals to the vesiculovirus Piry [PDF]
Journal of Hygiene, 1984 SUMMARYTo determine the pathogenic potential of the vesiculovirus Piry for domestic animals, two ponies, two steers, three sheep, three goats and three pigs were inoculated intradermally in the tongue or, in the case of the pigs, in the snout, heel and coronary band.
C. R. Wilks, J. A. House
openaire +5 more sources
Vesiculovirus Neutralization by Natural IgM and Complement [PDF]
Journal of Virology, 2014 ABSTRACTBecause of its very low human seroprevalence, vesicular stomatitis virus (VSV) has promise as a systemic oncolytic agent for human cancer therapy. However, as demonstrated in this report, the VSV infectious titer drops by 4 log units during the first hour of exposure to nonimmune human serum.
Stephen J. Russell +6 more
openaire +4 more sources