Results 41 to 50 of about 241,468 (251)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

RETRACTED ARTICLE: Screening for the presence and prevalence of Edwardsiella tarda infection in fish harvested from Lakes Zeway and Langano, Southern Oromia, Ethiopia

Cogent Food & Agriculture, 2016
A study was carried out from October 2009 to April 2010 with the objective of isolating E. tarda an important fish pathogen from fish harvested for human consumption from Lake Zeway and Langanoo.
Teshome Habtamu, Bedaso Kebede
doaj   +1 more source

Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles [PDF]

, 2012
The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels.
Mucalo, Michael R., Rathbone, Michael J.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Use of phytotherapics in dogs and cats. [PDF]

, 2008
Phytotherapy is one of the most utilized non conventional medicines (NCM) both in human and veterinary medicine. It can be used to mitigate and prevent slight diseases and to support conventional medicine using allopathic drugs. In this paper the Authors
AUTORE G., DE TOMMASI N., MARZOCCO S., RUSSO, ROSARIO, SEVERINO, LORELLA   +4 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Comparative Evaluation of Modified Vaccinia Ankara as a Surrogate Virus for Disinfectant Efficacy Testing Against AIV, FMDV, and ASFV

Viruses
Surrogate viruses provide a safe and scalable alternative for evaluating disinfectant efficacy when access to high-risk pathogens is restricted. This study evaluated the potential of Modified Vaccinia Ankara (MVA) virus, which can be handled under BSL-1 ...
Sok Song, Su-Jeong Kim, Kyu-Sik Shin, So-Hee Park, Yong Yi Joo, Bokhee Han, Cho-Yeon Lee, Gong-Woo Park, Hyun-Ok Ku, Wooseog Jeong, Choi-Kyu Park   +10 more
doaj   +1 more source

Proteomic analysis of the second-generation merozoites of Eimeria tenella under nitromezuril and ethanamizuril stress

Parasites & Vectors, 2019
Background Eimeria tenella is a highly pathogenic coccidian that causes avian coccidiosis. Both nitromezuril (NZL) and ethanamizuril (EZL) are novel triazine compounds with high anticoccidial activity, but the mechanisms of their action are still unclear.
Xue-Yan Li, Li-Li Liu, Min Zhang, Li-Fang Zhang, Xiao-Yang Wang, Mi Wang, Ke-Yu Zhang, Ying-Chun Liu, Chun-Mei Wang, Fei-Qun Xue, Chen-Zhong Fei   +10 more
doaj   +1 more source

Supply Chain and Delivery of Antimicrobial Drugs in Smallholder Livestock Production Systems in Uganda

Frontiers in Veterinary Science, 2021
This study assessed the veterinary drug supply chain in Uganda, the constraints faced by the actors, and how the challenges influence the use of antimicrobial (AMs) by livestock farmers.
Michel Mainack Dione, Winfred Christine Amia, Francis Ejobi, Emily Awuor Ouma, Barbara Wieland, Barbara Wieland   +5 more
doaj   +1 more source

Enrofloxacin-based therapeutic strategy for the prevention of endometritis in susceptible mares [PDF]

, 2010
Enrofloxacin (EFX) is often used empirically to prevent uterine infections in mares in order to improve efficiency on Commercial Embryo Transfer Farms.
Confalonieri, Alejandra, Fumuso, Elida Ana, García, J., González, C., Moreno, Laura Susana, Rivulgo, Virginia Margarita, Sanchez Bruni, Sergio Fabian, Sparo, Mónica Delfina   +7 more
core   +1 more source