Results 211 to 220 of about 57,494 (245)

Comparative analysis of CDR3 length-dependent patterns in VHHs. [PDF]

Front Immunol
Zhang L, Yang T, Zhang Y, Yan J, Li J, Xu W, Zhu W, Wang X.   +7 more
europepmc   +1 more source

Product Innovation and Transportation Technology in a Cournot Duopoly. [PDF]

A. Mantovani
core  

Applications of VHH in cancer diagnosis and therapy

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Detecting Nuclear Pore Complex assembly in living cells

Veldsink AC, Fischer JS, Terpstra HM, Mannino P, de Lange EM, Hell S, van Benthem KJ, Saba LJ, Steen A, Vlijm R, Heinemann M, Weis K, Lusk CP, Veenhoff LM.   +13 more
europepmc   +1 more source

STAMPS: Signal-peptide Transformer for Augmenting Mammalian Protein Secretion

Gabrielli J, Exposito-Rodriguez M, Briliūtė J, Burrell M, Thom G, Kontoravdi C, Ceroni F.   +6 more
europepmc   +1 more source

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Construction of Synthetic VHH Libraries in Ribosome Display Format

Methods in molecular biology, 2023
Single-domain antibodies, or VHH, represent an attractive molecular basis to design affinity proteins with favorable properties. Beyond high affinity and specificity for their cognate target, they usually show high stability and high production yields in bacteria, yeast, or mammalian cells.
Guilbaud, Audrey, Pecorari, Frédéric
openaire   +5 more sources

Small-Scale Secretory VHH Expression in Saccharomyces cerevisiae

Methods in molecular biology, 2022
After isolation of a single-domain antibody (VHH) binding to an antigen of interest, the soluble VHH is often produced in Escherichia coli. However, targeting VHH expression to the secretory pathway of Saccharomyces cerevisiae (baker's yeast) enables the secretion of correctly folded, soluble, disulfide-bonded, and N-glycosylated VHHs into the culture ...
Harmsen, Michiel M., van Hagen-van Setten, Marga, Willemsen, Peter T.J.   +2 more
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Abstract 4103: The IgG4 hinge with CD28 transmembrane domain improves VHH-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer

Cancer Research, 2023
Heterogeneous antigen expression is a key barrier influencing the activity of chimeric antigen receptor (CAR) T cells in solid tumors. Here, we developed CAR T cells targeting glypican-1 (GPC1), an oncofetal antigen expressed in pancreatic cancer.
Nan Li, Alex Quan, Dan Li, Hua Ren, Weiming Ni, Jing Zhou, R. Cachau, Mitchell Ho   +7 more
semanticscholar   +1 more source