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Intra-cellular VHH targeting the FSHR and LHR

Intracellular variable fragments from heavy-chain antibody from camelids (intra-VHH) have beensuccessfully used as chaperones to solve the 3D structure of active G protein-coupled receptors(GPCRs) bound to their cognate transducers. They may also provide a better understanding onthe relationships between receptor conformation and signalling activity ...
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Structure and Function of Camelid VHH

Jianliang Xu, Kai Xu
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