Results 71 to 80 of about 1,940,966 (390)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Decoration and Use of Carya Speciees Planting in Urban Gardening
Науковий вісник НЛТУ України, 2017 The main structural component of the park landscape is the tree and shrub vegetation. Carya is the species that depends a lot on growing conditions. An objective assessment of this species can be given only during long-term observations, including the ...
V.O. Bozhok
doaj +1 more source
Pharmaceutical Biology, 2022 Context M2 phenotype macrophage polarization is an attractive target for therapeutic intervention. Asiaticoside (ATS) has multiple pharmacological functions.Objective This study investigates the effect of ATS on M2 phenotype macrophage polarization in ...
Dang-ke Li, Guang-hui Wang
doaj +1 more source
Catastrophe Management and Inter-Reserve Distance for Marine Reserve Networks [PDF]
Ecol Model 201 (2007) 82-88, 2003 We consider the optimal spacing between marine reserves for maximising the viability of a species occupying a reserve network. The closer the networks are placed together, the higher the probability of colonisation of an empty reserve by an occupied reserve, thus increasing population viability. However, the closer the networks are placed together, the
arxiv +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
Frontiers in Oncology, 2019 Surfactant Protein D (SP-D), a pattern recognition innate immune molecule, has been implicated in the immune surveillance against cancer. A recent report showed an association of decreased SP-D expression in human prostate adenocarcinoma with an ...
Gargi Thakur +10 more
doaj +1 more source
Thoracic Cancer, 2020 Background Circular RNAs (circRNAs) participate in the development of human cancers by regulating multiple cell processes. CircRNA antisense to the cerebellar degeneration‐related protein 1 transcript (circCDR1as) expression is dysregulated in many ...
Yaming Li +5 more
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Journal of Threatened Taxa, 2016 Gymnacranthera canarica (King) Warb. is an exclusive Myristica swamp species endemic to the Western Ghats. The Myristica swamp is a Critically Endangered ecosystem.
K. Keshavachandra, G. Krishnakumar
doaj +1 more source