Results 131 to 140 of about 509,068 (300)

Effectiveness of an educational intervention on knowledge-attitude-practice of older adults’ caregivers

Revista Brasileira de Enfermagem
Objective: To compare the knowledge, attitude and practice of older adults’ caregivers before and after an educational intervention in the domains of the care between caregiver and older adult, feeding, bathing, hygiene and mobility and transportation ...
Andréa Carvalho Araújo Moreira, Maria Josefina da Silva, Juan José Tirado Darder, Janaína Fonseca Victor Coutinho, Maristela Inês Osawa Vasconcelos, Marília Braga Marques   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

LTSS Choices: Adult Family Care - A Viable Alternative to Nursing Homes [PDF]

, 2021
Robert Mollica, Kathleen Ujvari
openaire   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

E-grocery continuance among older Malaysians: extending the technology acceptance model with psychological and physical health factors

Cogent Business & Management
As the population ages, traditional grocery shopping presents challenges for older adults, increasing food insecurity and reducing independence. E-grocery services provide a viable solution, yet their sustained use remains underexplored.
Yee-Yann Yap, Siow-Hooi Tan, Man Seong Chan   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Childhood and Marketing: A Briefing [PDF]

, 2009
The 
present
 briefing
 overviews
 and
 samples
 a 
number 
of 
issues
 relating 
to
 childhood
 and 
business ...
Spadaro-Bliss, Simon
core   +1 more source

OLDER ADULT HOME HEALTH AIDES: A VIABLE OPTION

Innovation in Aging, 2017
G. McGhan, D. McCaughey, R. Herald
openaire   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source