Results 121 to 130 of about 509,068 (300)

Understanding Travel Behaviors and Mobility Challenges Faced by Older Adults during the COVID-19 Pandemic

open access: yesJournal of Ageing and Longevity
Background: During the COVID-19 pandemic, older adults were considered one of the most vulnerable groups as they faced obstacles when traveling for daily activities.
Troyee Saha   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Compatibility of Glyphosate with Galerucella calmariensis; a Biological Control Agent for Purple Loosestrife (Lythrum salicaria) [PDF]

open access: yes, 1999
By integrating Galerucella calmariensis with glyphosate there is potential to achieve both immediate and sustained control of purple loosestrife (Lythrum salicaria).
Gabor, T. Shane   +2 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Leveraging State Economic Development Resources to Create Job Opportunities for People with Disabilities [PDF]

open access: yes, 2009
A 2009 research brief produced for the NTAR Leadership Center, a consortium led by the John H. Heldrich Center for Workforce Development at Rutgers, The State University of New Jersey.
Allison Kopicki   +2 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

How Housing Matters: Americans' Attitudes Transformed by the Housing Crisis & Changing Lifestyles [PDF]

open access: yes, 2013
On behalf of the MacArthur Foundation, Hart Research Associates undertook a comprehensive research study to explore the role that housing plays in Americans' lives and to inform the policy discourse on housing in America.

core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

SSI and Postsecondary Education Support for Students with Disabilities [PDF]

open access: yes, 2002
Young adults with disabilities who receive Supplementary Security Income (SSI) may think that postsecondary education is beyond their financial reach because their SSI benefits do not provide them with enough income for living and medical expenses after ...
Golden, Thomas P., Jones, Megan A.
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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