Results 11 to 20 of about 915,858 (361)

Nanosecond pulsed electric field (nsPEF) and vaccines: a novel technique for the inactivation of SARS-CoV-2 and other viruses?

open access: yesAnnals of Medicine, 2022
Since the beginning of 2020, worldwide attention has been focused on SARS-CoV-2, the second strain of the severe acute respiratory syndrome virus.
A. R. Ruiz-Fernández   +2 more
doaj   +1 more source

A pandemia da COVID-19 e as mudanças no estilo de vida dos brasileiros adultos: um estudo transversal, 2020

open access: yesEpidemiologia e Serviços de Saúde, 2020
Resumo Objetivo Descrever as mudanças nos estilos de vida, quanto ao consumo de tabaco, bebidas alcoólicas, alimentação e atividade física, no período de restrição social consequente à pandemia da COVID-19.
D. Malta   +14 more
semanticscholar   +1 more source

Correlação entre uso de álcool e drogas e o risco de suicídio em pessoas diagnosticadas com transtorno afetivo bipolar: uma visão geral

open access: yesDebates em Psiquiatria, 2023
Introdução: O transtorno afetivo bipolar (TAB) é uma condição psiquiátrica complexa, caracterizada por alterações extremas de humor, incluindo episódios de mania e depressão. A relação entre o uso de álcool, drogas e o risco de suicídio em pacientes com
Stéfanie Venturini Fanton   +5 more
doaj   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä   +18 more
wiley   +1 more source

Health‐related quality of life following total minimally invasive, hybrid minimally invasive or open oesophagectomy: a population‐based cohort study

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
All patients operated for oesophageal cancer in Sweden from 2013 to April 2018 were identified, and 246 patients were recruited to this population‐based nationwide Swedish study. The results show that longitudinal health‐related quality of life after minimally invasive oesophagectomy was similar to that of the open surgical approach.
F. Klevebro   +4 more
wiley   +1 more source

Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro

open access: yesBiological Research, 2021
Background The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, apoptosis and invasiveness ...
Nicole Farfán   +4 more
doaj   +1 more source

Draft genome sequence of the type strain of the sulfur-oxidizing acidophile, Acidithiobacillus albertensis (DSM 14366)

open access: yesStandards in Genomic Sciences, 2017
Acidithiobacillus albertensis is an extremely acidophilic, mesophilic, obligatory autotrophic sulfur-oxidizer, with potential importance in the bioleaching of sulfidic metal ores, first described in the 1980s. Here we present the draft genome sequence of
Matías Castro   +11 more
doaj   +1 more source

Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancer

open access: yesOncoImmunology, 2023
Gallbladder cancer (GBC) is commonly diagnosed at late stages when conventional treatments achieve only modest clinical benefit. Therefore, effective treatments for advanced GBC are needed.
Ernesto Lopez   +11 more
doaj   +1 more source

GPR43 stimulation on TCRαβ+ intraepithelial colonic lymphocytes inhibits the recruitment of encephalitogenic T-cells into the central nervous system and attenuates the development of autoimmunity

open access: yesJournal of Neuroinflammation, 2023
Introduction Gut microbiota plays a critical role in the regulation of immune homeostasis. Accordingly, several autoimmune disorders have been associated with dysbiosis in the gut microbiota. Notably, the dysbiosis associated with central nervous system (
Carolina Prado   +6 more
doaj   +1 more source

Pangenome-level analysis of nucleoid-associated proteins in the Acidithiobacillia class: insights into their functional roles in mobile genetic elements biology

open access: yesFrontiers in Microbiology, 2023
Mobile genetic elements (MGEs) are relevant agents in bacterial adaptation and evolutionary diversification. Stable appropriation of these DNA elements depends on host factors, among which are the nucleoid-associated proteins (NAPs).
Simón Beard   +12 more
doaj   +1 more source

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