Results 31 to 40 of about 2,726 (170)
, 1986 Thermodynamic and biochemical factors such as membrane diffusion and membrane metabolism play an integral role in rational dosage form design (prodrug).
Durrani, Manzer Jamil Khan
core +5 more sources
The Concise Guide to PHARMACOLOGY 2023/24: Transporters
British Journal of Pharmacology, Volume 180, Issue S2, Page S374-S469, October 2023., 2023 The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links
Stephen P. H. Alexander +27 more
wiley +1 more source
In Silico Exploration of Potential Natural Inhibitors against SARS-Cov-2 nsp10
Molecules, 2021 In continuation of our previous effort, different in silico selection methods were applied to 310 naturally isolated metabolites that exhibited antiviral potentialities before.
Ibrahim H. Eissa +5 more
doaj +1 more source
The FEBS Journal, Volume 290, Issue 20, Page 4899-4920, October 2023., 2023 The expanding fields of mRNA therapeutics and epitranscriptomics require methods to produce RNA containing unnatural nucleosides. We have devised an adaptable system for the enzymatic triphosphorylation of a wide variety of non‐canonical nucleosides. This allows in vitro transcription of RNA containing modified nucleoside analogues and subsequent mRNA ...
Patricia Benčić +9 more
wiley +1 more source
Neonatal herpes simplex virus infection: From the maternal infection to the child outcome
Journal of Medical Virology, Volume 95, Issue 8, August 2023., 2023 Abstract This review examines the recent literature on the management of herpes simplex virus (HSV) infections in neonates. We summarized the three clinical categories of maternal HSV infection during pregnancy (primary first episode, nonprimary first episode, or recurrent episode) and the mechanisms of fetal damage.
Domenico Umberto De Rose +9 more
wiley +1 more source
Marine Sponge is a Promising Natural Source of Anti-SARS-CoV-2 Scaffold
Frontiers in Pharmacology, 2021 The current pandemic caused by SARS-CoV2 and named COVID-19 urgent the need for novel lead antiviral drugs. Recently, United States Food and Drug Administration (FDA) approved the use of remdesivir as anti-SARS-CoV-2.
Alshaimaa M. Hamoda +12 more
doaj +1 more source
Herpes Zoster Encephalitis: Successful Therapy with Vidarabine [PDF]
, 1980 A 77-year-old woman was seen who had encephalitis complicating trigeminal herpes zoster. Diagnosis was made by clinical and cerebrospinal fluid findings and electroencephalogram.
Wees, Steve J., Madhavan, Tom
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Pharmacokinetics of Paracetamol, Diclofenac and Vidarabine during Plasma Exchange
, 1988 In order to establish guidelines for prescribing drugs in patients treated with plasma exchange (PE), we studied the pharmacokinetics of paracetamol (5 patients), diclofenac (4 patients) and vidarabine (3 patients) during one or several PE. Results were
A. Leon +4 more
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