Results 11 to 20 of about 12,236 (230)
Vigabatrin-Induced Encephalopathy in a 5.5-Month-Old Girl with Infantile Spasms due to Tuberous Sclerosis [PDF]
Case Reports in Pediatrics, 2019 A 5.5-month-old female infant with tuberous sclerosis complex presented with infantile spasms and was treated with vigabatrin. As her condition did not improve, she was given adrenocorticotropic hormone (ACTH) intramuscularly which stopped the spasms and
Eleni Klinaki +6 more
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Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21 [PDF]
Frontiers in PediatricsBackgroundInfantile Epileptic Spasms Syndrome (IESS) is the most common epilepsy syndrome in children with trisomy 21. First-line standard treatments for IESS include adrenocorticotropic hormone (ACTH), oral corticosteroids, and vigabatrin.
Henry Chen +13 more
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UK Multicenter Randomized Trial of Hormonal Treatments Vs Vigabatrin for Infantile Spasms [PDF]
Pediatric Neurology Briefs, 2010 The UK Infantile Spasms Multicenter Study previously showed that seizure control after 14 days and development at 14 months are better following hormonal treatments (prednisolone or tetracosactide depot) than following vigabatrin.
J Gordon Millichap
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Tuberous sclerosis presents with self-injurious behavior as an adverse event of Vigabatrin. [PDF]
Indian J PsychiatryMeghana V, Sakhardande KA, Thomas TL.
europepmc +2 more sources
Short Course and Early Switch of Vigabatrin for Infantile spasms [PDF]
Annals of Child Neurology, 2020 Purpose Vigabatrin has proven efficacy in the treatment of infantile spasms, but it carries the risk of irreversible visual field constriction. The incidence of vigabatrin-induced visual field constriction seems to depend on the extent of vigabatrin ...
Hye Won Ryu +6 more
doaj +1 more source
Neurotherapeutics, 2007 Refractory epilepsies such as infantile spasms (IS) and complex partial seizures (CPS) can have a severe negative impact on the neurological integrity and quality of life of affected patients, in addition to drastically increasing their risk of premature mortality.
James W, Wheless +2 more
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EVALUATION OF THE STABILITY OF VIGABATRIN IN HOSPITALAR EXTEMPORANEOUS FORMULATIONS
Drug Analytical Research, 2019 The aim of this study was to analyze the chemical stability of the anticonvulsant vigabatrin extemporaneous formulation from tablets in storage conditions of different temperatures and types of packaging used.
Marcio Vinicius Ayres +4 more
doaj +9 more sources
Peripheral visual field defect of vigabatrin in pediatric epilepsy: A review
The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2023 Vigabatrin is the medication used for the treatment of infantile spasms and refractory complex partial seizures, but its usage has always been contradictory due to its effect on vision.
Umme Habeeba A. Pathan +3 more
doaj +1 more source
Developmental Medicine and Child Neurology, 2001 The new antiepileptic drugs introduced over the last decade provide a welcome increase in the therapeutic options available for the 25% of children with epilepsy who remain refractory to traditional therapy.1 In the mid 1980s, vigabatrin (VGB) was the first of these to be made available in clinical practice.
H, Lewis, S J, Wallace
openaire +2 more sources