Results 31 to 40 of about 66,916 (254)
Cells, 2019 Ageing is the result of changes in biochemical and biophysical processes at the cellular level that lead to progressive organ decline. Here we focus on the biophysical changes that impair cellular function of human dermal fibroblasts using donors of ...
Kristina Sliogeryte, Núria Gavara
doaj +1 more source
Characterization of cells of amniotic fluids by immunological identification of intermediate-sized filaments: Presence of cells of different tissue origin [PDF]
, 1981 Antibodies against intermediate-sized filaments, of the prekeratin or vimentin type, were used to investigate the presence of these filaments by indirect immunofluorescence microscopy in cultured and non-cultured amniotic fluid cells, in frozen sections ...
Cremer, Marion +4 more
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Vimentin regulates peripheral nerve myelination [PDF]
Development, 2012 Myelination is a complex process that requires coordinated Schwann cell-axon interactions during development and regeneration. Positive and negative regulators of myelination have been recently described, and can belong either to Schwann cells or neurons.
Triolo D +11 more
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Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific [PDF]
, 2015 Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells.
Ali, RR +6 more
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Site-Specific Labeling of Proteins with Near-IR Heptamethine Cyanine Dyes
Molecules, 2018 Convenient labeling of proteins is important for observing its function under physiological conditions. In tissues particularly, heptamethine cyanine dyes (Cy-7) are valuable because they absorb in the near-infrared (NIR) region (750⁻900 nm) where ...
Chen-Ming Lin +2 more
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Cells, 2020 Long intergenic non-coding RNAs (lincRNAs) play important roles in human cancer development, including cell differentiation, apoptosis, and tumor progression. However, their underlying mechanisms of action are largely unknown at present.
Syuan-Ling Lin +6 more
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Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]
, 2018 Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton +58 more
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Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples [PDF]
, 2013 Emerging evidence has shown that the tumor microenvironment plays a crucial role in prostate cancer (PCa) development and progression. However, the mechanism(s) through which stromal cells regulate epithelial cells and the differences among prostatic ...
Clemente, Luigi Di +7 more
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Vimentin Knockdown Decreases Corneal Opacity [PDF]
Investigative Opthalmology & Visual Science, 2014 Wound induced corneal fibrosis can lead to permanent visual impairment. Keratocyte activation and differentiation play a key role in fibrosis, and vimentin, a major structural type III intermediate filament, is a required component of this process. The purpose of our study was to develop a nonviral therapeutic strategy for treating corneal fibrosis in ...
Subrata K, Das +8 more
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DACH1 suppresses breast cancer as a negative regulator of CD44. [PDF]
, 2017 Dachshund homolog 1 (DACH1), a key cell fate determination factor, contributes to tumorigenesis, invasion, metastasis of human breast neoplasm. However, the exact molecular mechanisms for the anti-tumor roles of DACH1 in breast carcinoma are still lack ...
Kuang, Dong +6 more
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