Results 51 to 60 of about 53,171 (233)

Continuous Evolution System Based on Toxin–Antitoxin System Combined with Base Deaminase Accelerates the In Vivo Modification of Target Proteins

open access: yesAdvanced Science, EarlyView.
The promoted Escherichia coli‐assisted continuous evolution (PEACE) system operates through a stringent three step genetic circuit: target gene mutation via a deaminase–T7 RNA polymerase (T7 RNAP) fusion, coupling variant function to antitoxin expression, and growth based selection of surviving cells.
Xinyu Zhang   +10 more
wiley   +1 more source

INPATIENTS NUTRITIONAL REQUIREMENTS INDICATOR AT ARMY HOSPITAL DR. SOEPRAOEN MALANG

open access: yesJurnal Ners, 2017
Introduction: Patient acceptance to diet in fl uences patient intake during the hospitalization. Patient acceptance on meals provided by the hospital can be seen from the left over.
Kumboyono Kumboyono, Vina Vina
doaj   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

open access: yesAdvanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang   +19 more
wiley   +1 more source

Aromatski profil vina priznatih klonova sorte 'Graševina'

open access: yesGlasnik Zaštite Bilja, 2023
Klonska selekcija sorte 'Graševina' rezultirala je registracijom četiri klona, OB-412, OB-414, OB-435 i OB-445. S obzirom na raširenost sorte 'Graševina' u Hrvatskoj, kvaliteta vina je vrlo važan čimbenik u prihvaćenosti od strane potrošača.
Iva Šikuten   +4 more
doaj  

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Povijesni pregled proizvodnje vina u Hercegovini

open access: yesGlasnik Zaštite Bilja, 2022
Prema povijesnim podatcima vinova loza se na području Hercegovine uzgajala i u vrijeme starih Ilira, odnosno plemena Daorsa. Ljetopisi navode da su Rimljani, Dubrovčani, Turci i Habsburgovci bili pohlepni za ovom zemljom upravo zbog vinove loze i grožđa.
Nino Rotim
doaj  

Oral history interview with Mick and Vina Weiberg

open access: yes, 2021
Mick and Vina Weiberg share memories of their son Jared who died in the 2001 Oklahoma State University (OSU) plane crash. They recall his childhood, his work ethic, his dream of being a college basketball coach, and his genuine love of people.
Weiberg, Mick; Weiberg, Vina
core  

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

Prilagodba ekspertnih ocjenjivača vina manje poznatim metodama senzornih ispitivanja bez prethodne pripreme

open access: yesGlasnik Zaštite Bilja, 2022
Senzorna ispitivanja vina provode ocjenjivači koje se obično bira i priprema sukladno metodi ispitivanja i njihove vještine mogu varirati ovisno o različitim čimbenicima.
Ivana Alpeza, Katarina Rončević
doaj  

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