Results 51 to 60 of about 86,503 (159)
Vincristine is an essential chemotherapy agent administered for various pediatric cancers including acute lymphoblastic leukemia (ALL). While multi-agent chemotherapy for pediatric ALL is highly curative, with survival approaching 95%, it carries the ...
Jonas Yeung +10 more
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The terpene-indole alkaloids loaded erythrocytes as a drug carrier: design and assessment
The aim of this work was to elucidate the certain parameters (morphological, physicochemical) of terpene-indole alkaloids (TIAs) encapsulated human erythrocytes as a drug delivery system, and in addition to providing insight into the functional state of ...
Halahakoon Mudiyanselge Amila Jeewantha +1 more
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Vincristine Neurotoxicity (Cont.)
To the Editor: We read with interest the case, recently reported by P. L. Weiden and S. E. Wright, concerning a peculiar sensitivity to vincristine observed in a patient with the Charcot–Marie–Tooth syndrome (N Engl J Med 286: 1369, 1972).
Kenis, Yvon +3 more
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Vincristine induced CL content changes.
(A) Percentage of CL species in control and after 48-hr of vincristine treatment. Experiments are in triplicates and analyzed by t-test (*p p p < 0.001). (B) The changes of CL contents after 48-hr of vincristine treatment.
Jui-Fen Chan (3120369) +2 more
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Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes. [PDF]
Vincristine is an effective chemotherapeutic drug for various cancers, including acute lymphoblastic leukemia (ALL). Unfortunately, clinical utility is restricted by dose-limiting vincristine-induced peripheral neuropathies (VIPN). We sought to determine
Bruce C. Carleton +15 more
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Vincristine-induced neurotoxicity: electrophysiological features in children
Objective: Neuropathy caused by vincristine toxicity can be diagnosed by electrophysiological examination.
TEMUÇİN, ÇAĞRI MESUT, YILDIZ, FERAH
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Ying Liu,1,* Man He,1,* Mengmeng Niu,1 Yiqing Zhao,1 Yuanzhang Zhu,1 Zhenhua Li,2 Nianping Feng1 1Department of Pharmaceutical Sciences, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China;
Liu Y +6 more
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Mononeuropathy due to vincristine toxicity.
Vincristine sulfate is a known neurotoxin. Peripheral neuropathy is the most common toxic manifestation and is usually of the symmetrical, mixed, sensory-motor type.
Prager, D, Levitt, Lawrence
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A ten year old mongrel bitch was diagnosed with a primary vulvar transmissible venereal tumor (TVT) causing subcutaneous, mammary and splenic metastasis and it was successfully treated with vincristine. Four months later the animal presented neurological
Pedro PINCZOWSKI +5 more
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Yuzhen Xu,1 Liyan Qiu2 1College of Pharmaceutical Sciences, 2Ministry of Education Key Laboratory of Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, People’s Republic of China ...
Qiu LY, Xu YZ
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