Results 51 to 60 of about 86,503 (159)

Vincristine-induced brain toxicity is reduced with prevention of peripheral axon degeneration in Sarm1 knockout mice

open access: yesActa Neuropathologica Communications
Vincristine is an essential chemotherapy agent administered for various pediatric cancers including acute lymphoblastic leukemia (ALL). While multi-agent chemotherapy for pediatric ALL is highly curative, with survival approaching 95%, it carries the ...
Jonas Yeung   +10 more
doaj   +1 more source

The terpene-indole alkaloids loaded erythrocytes as a drug carrier: design and assessment

open access: yesRussian Open Medical Journal, 2018
The aim of this work was to elucidate the certain parameters (morphological, physicochemical) of terpene-indole alkaloids (TIAs) encapsulated human erythrocytes as a drug delivery system, and in addition to providing insight into the functional state of ...
Halahakoon Mudiyanselge Amila Jeewantha   +1 more
doaj   +1 more source

Vincristine Neurotoxicity (Cont.)

open access: yes, 1972
To the Editor: We read with interest the case, recently reported by P. L. Weiden and S. E. Wright, concerning a peculiar sensitivity to vincristine observed in a patient with the Charcot–Marie–Tooth syndrome (N Engl J Med 286: 1369, 1972).
Kenis, Yvon   +3 more
core   +1 more source

Vincristine induced CL content changes.

open access: yes, 2016
(A) Percentage of CL species in control and after 48-hr of vincristine treatment. Experiments are in triplicates and analyzed by t-test (*p p p < 0.001). (B) The changes of CL contents after 48-hr of vincristine treatment.
Jui-Fen Chan (3120369)   +2 more
core   +1 more source

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy Implicates Pharmacokinetic and Inherited Neuropathy Genes. [PDF]

open access: yes, 2019
Vincristine is an effective chemotherapeutic drug for various cancers, including acute lymphoblastic leukemia (ALL). Unfortunately, clinical utility is restricted by dose-limiting vincristine-induced peripheral neuropathies (VIPN). We sought to determine
Bruce C. Carleton   +15 more
core   +2 more sources

Vincristine-induced neurotoxicity: electrophysiological features in children

open access: yes, 2016
Objective: Neuropathy caused by vincristine toxicity can be diagnosed by electrophysiological examination.
TEMUÇİN, ÇAĞRI MESUT, YILDIZ, FERAH
core   +1 more source

Delivery of vincristine sulfate-conjugated gold nanoparticles using liposomes: a light-responsive nanocarrier with enhanced antitumor efficiency

open access: yes, 2015
Ying Liu,1,* Man He,1,* Mengmeng Niu,1 Yiqing Zhao,1 Yuanzhang Zhu,1 Zhenhua Li,2 Nianping Feng1 1Department of Pharmaceutical Sciences, School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China;
Liu Y   +6 more
core  

Mononeuropathy due to vincristine toxicity.

open access: yes, 1975
Vincristine sulfate is a known neurotoxin. Peripheral neuropathy is the most common toxic manifestation and is usually of the symmetrical, mixed, sensory-motor type.
Prager, D, Levitt, Lawrence
core   +1 more source

Brain Metastasis In A Case Of Canine Transmissible Venereal Tumor After A Supposed Successful Treatment With Vincristine Sulfate

open access: yesActa Veterinaria, 2015
A ten year old mongrel bitch was diagnosed with a primary vulvar transmissible venereal tumor (TVT) causing subcutaneous, mammary and splenic metastasis and it was successfully treated with vincristine. Four months later the animal presented neurological
Pedro PINCZOWSKI   +5 more
doaj   +1 more source

Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes

open access: yes, 2015
Yuzhen Xu,1 Liyan Qiu2 1College of Pharmaceutical Sciences, 2Ministry of Education Key Laboratory of Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, People’s Republic of China ...
Qiu LY, Xu YZ
core  

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