Results 51 to 60 of about 71,512 (251)
Vincristine is an essential chemotherapy agent administered for various pediatric cancers including acute lymphoblastic leukemia (ALL). While multi-agent chemotherapy for pediatric ALL is highly curative, with survival approaching 95%, it carries the ...
Jonas Yeung +10 more
doaj +1 more source
The terpene-indole alkaloids loaded erythrocytes as a drug carrier: design and assessment
The aim of this work was to elucidate the certain parameters (morphological, physicochemical) of terpene-indole alkaloids (TIAs) encapsulated human erythrocytes as a drug delivery system, and in addition to providing insight into the functional state of ...
Halahakoon Mudiyanselge Amila Jeewantha +1 more
doaj +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
ABSTRACT Treatment of sarcoma includes high‐dose anthracyclines, which can cause cardiotoxicity. This study assesses the correlation of cardiac biomarkers and echocardiographic parameters on asymptomatic cardiotoxicity in sarcoma patients treated with anthracyclines.
Elissa A. S. Polomski +6 more
wiley +1 more source
Successful propranolol therapy for infantile hepatic hemangioma with cardiac failure
Abstract Infantile hepatic hemangioma (IHH) can cause severe complications such as high‐output cardiac failure and growth faltering, requiring prompt diagnosis and intervention. In the absence of standardized treatment guidelines, propranolol has emerged as an effective and well‐tolerated therapy.
Fadhel Al Ateeqi +4 more
wiley +1 more source
A Case of Cutaneous B Lymphoblastic Lymphoma With Multiple Cutaneous Tumors
ABSTRACT A 17‐year‐old Japanese male patient was referred to our hospital due to an erythematous tumor on part of the right mandible that had developed 3 months earlier, and similar tumors had appeared on the trunk and lower extremities. A complete blood count showed no specific abnormalities.
Tomomichi Shimizu +4 more
wiley +1 more source
Nail Toxicities Associated With Anticancer Therapies in Children
ABSTRACT Nail toxicities are a frequent yet often underrecognized component of dermatologic adverse events in children receiving anticancer therapies. Both conventional cytotoxic chemotherapy and newer targeted agents can affect the nail matrix, nail bed and periungual tissues, producing a broad spectrum of clinical manifestations that range from ...
Luca Rapparini, Michela Starace
wiley +1 more source
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu +5 more
wiley +1 more source
Residual and recurrent disease in advanced juvenile nasopharyngeal angiofibromas (JNAs) demonstrate spontaneous involution, reduction in size, or long‐term stability following initial treatment in 95% of patients. In this systematic review of 131 patients with advanced JNA, only 2% of patients demonstrated disease progression during surveillance, but ...
Shivani Angelique Kumar +2 more
wiley +1 more source
A ten year old mongrel bitch was diagnosed with a primary vulvar transmissible venereal tumor (TVT) causing subcutaneous, mammary and splenic metastasis and it was successfully treated with vincristine. Four months later the animal presented neurological
Pedro PINCZOWSKI +5 more
doaj +1 more source

