Results 41 to 50 of about 15,616 (165)

Neoadjuvant Combination Chemotherapy with Pegylated Liposomal Doxorubicin and Vinorelbine for Locally Advanced Breast Cancer

Cancer Biology & Medicine, 2010
OBJECTIVE In China, vinorelbine plus an anthracycline is a common neoadjuvant regimen for locally-advanced breast cancer (LABC). Pegylated liposomal doxorubicin (PLD) is an alternate anthracycline formulation with a more favorable safety profi le ...
Zhen-zhou SHEN, Zhi-min SHAO, Bing-he XU
doaj   +1 more source

Survival outcomes in dogs treated with vinorelbine‐based adjuvant treatment following surgical resection of grade II and III pulmonary carcinoma

Journal of Small Animal Practice, EarlyView.
Objectives Pulmonary carcinoma in dogs is commonly managed with surgical resection; however, the role of adjuvant chemotherapy for grade II and III carcinomas remains unclear. This retrospective multicentre study investigated the outcomes in dogs treated with vinorelbine‐based adjuvant treatment (as monotherapy or combined chemotherapy) following ...
N. Wong, L. Brockley, S. Rajan, J. Yu
wiley   +1 more source

Analysis of Histopathologic Parameters and Patterns of Invasion in Oral Squamous Cell Carcinoma and Their Correlation With Patient Survival

Oral Diseases, EarlyView.
ABSTRACT Introduction Oral squamous cell carcinoma is the most prevalent malignant neoplasm in the head and neck region, and its prognosis is influenced by various histopathological and clinical factors. pTNM tumor staging and invasion patterns are fundamental for predicting therapeutic response and patient survival.
Ana Mirian da Silva Cavalcante, Janderson Fernando da Silva, Tayane Oliveira Gonçalves, Fabrício Bitu Sousa, Erick Ibraim Carlos da Costa, Ana Paula Negreiros Nunes Alves, Jennifer Viana Barbosa, Dayrine Silveira de Paula, Paulo Goberlânio de Barros Silva, Thinali Sousa Dantas   +9 more
wiley   +1 more source

A Phase I Comparative Pharmacokinetic and Safety Study of Two Intravenous Formulations of Vinorelbine in Patients With Advanced Non-Small Cell Lung Cancer

Frontiers in Pharmacology, 2019
Purpose: The aim of this study was to compare the pharmacokinetics and safety between two vinorelbine formulations [a new oil-in-water emulsion formulation (ANX) versus a previously marketed solution formulation (Navelbine)] in Chinese patients with ...
Guolan Wu, Guolan Wu, Lihua Wu, Lihua Wu, Huili Zhou, Huili Zhou, Meihua Lin, Meihua Lin, Ling Peng, Yina Wang, You Zhai, You Zhai, Xingjiang Hu, Xingjiang Hu, Yunliang Zheng, Yunliang Zheng, Duo Lv, Duo Lv, Jian Liu, Jian Liu, Jianzhong Shentu, Jianzhong Shentu   +21 more
doaj   +1 more source

Clinicogenomic Features and Outcomes of Adenoid Cystic Carcinoma With Central Nervous System Metastases: A Single‐Institution Cohort Study

Head &Neck, Volume 48, Issue 11, Page 3193-3201, November 2026.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is a rare malignancy with a propensity for perineural invasion and hematogenous spread. Central nervous system (CNS) involvement is uncommon, and detailed clinical and genomic data on this aspect of the disease remain limited.
Omar Elghawy, Jack Stylli, Martin Kurian, Eitan Halper‐Stromberg, Aditi Singh, Christopher D'Avella, Lee Hartner, Roger B. Cohen   +7 more
wiley   +1 more source

Vinorelbine- Autophagy Agent Combinations Induce Synergistic Cytotoxicity in SH-SY5Y Neuroblastoma Cells

Recent Trends in Pharmacology
Objective: To investigate whether pharmacological agents associated with autophagy induction or inhibition modulate vinorelbine-induced cytotoxic responses in SH-SY5Y neuroblastoma cells.
Berna Yıldırım, Melike Seçilmiş, Burcu Biltekin, Mete Hakan Karalök, Turgay Barut, Ayhan Bilir   +5 more
doaj   +1 more source

Vinorelbine as a radiosensitizer in Pakistani patients with locally advanced unresectable head & neck cancer (HNC) in tertiary care hospital of Pakistan

International Journal of Endorsing Health Science Research, 2019
Background: Head and neck cancer (HNC) is one of the most common cancers in Pakistan. Disease free survival in HNC remains poor due to inefficient loco-regional disease control. The aim of the present study was to assess the response rate and toxicity of
Rana Atique Anwer Khan, Ahmed Ijaz Masood, Sadaqat Ali Gorchani, Muhammad Junaid, Ali Yasir Khan   +4 more
doaj   +1 more source

Serial growth plate monitoring in a 3‐month‐old Labrador retriever receiving vinblastine chemotherapy

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract A 3‐month‐old, male, entire Labrador retriever was presented for evaluation of a congenital mast cell tumour of the right pinna. Pinnectomy and regional lymphadenectomy confirmed a high‐grade mast cell tumour with nodal pre‐metastasis. Eight vinblastine chemotherapy treatments were administered over 12 weeks.
Paige A. A. Brown, Kate M. Sippel, Alison Masyr   +2 more
wiley   +1 more source

Vinca Alkaloids

International Journal of Preventive Medicine, 2013
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects.
Maryam Moudi, Rusea Go, Christina Yong Seok Yien, Mohd Nazre   +3 more
doaj  

Vinorelbine causes a neuropathic pain-like state in mice via STING and MNK1 signaling associated with type I interferon induction

iScience
Summary: Type I interferons (IFNs) increase the excitability of dorsal root ganglia (DRGs) neurons via MNK-eIF4E signaling to promote pain sensitization in mice.
Úrzula Franco-Enzástiga, Keerthana Natarajan, Eric T. David, Krish Patel, Abhira Ravirala, Theodore J. Price   +5 more
doaj   +1 more source