Results 31 to 40 of about 10,523,720 (359)

Mechanisms of viral inflammation and disease in humans

open access: yesScience, 2021
Description Disease and accompanying inflammation are uncommon outcomes of viral infection in humans. Clinical inflammation occurs if steady-state cell-intrinsic and leukocytic immunity to viruses fails.
J. Casanova, L. Abel
semanticscholar   +1 more source

Incidence of acute diarrheal illness in Chinese communities: a meta-analysis

open access: yesBMC Gastroenterology, 2018
Background Acute diarrheal illness (ADI) is an important public health problem worldwide. We estimated the morbidity, distribution, and burden of self-reported ADI in China over the last three decades. Methods We used the keywords “diarrhea and morbidity”
Pengwei Cui   +3 more
doaj   +1 more source

SARS-CoV-2 viral load is associated with increased disease severity and mortality

open access: yesNature Communications, 2020
The relationship between SARS-CoV-2 viral load and risk of disease progression remains largely undefined in coronavirus disease 2019 (COVID-19). Here, we quantify SARS-CoV-2 viral load from participants with a diverse range of COVID-19 disease severity ...
Jesse Fajnzylber   +130 more
semanticscholar   +1 more source

The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes

open access: yesMucosal Immunology, 2021
Bacteria that colonize the human gastrointestinal tract are essential for good health. The gut microbiota has a critical role in pulmonary immunity and host’s defense against viral respiratory infections. The gut microbiota’s composition and function can
V. Sencio, M. G. Machado, F. Trottein
semanticscholar   +1 more source

Upregulation of nuclear factor E2-related factor 2 (Nrf2) represses the replication of herpes simplex virus type 1

open access: yesVirology Journal, 2022
Background Nuclear factor E2-related factor 2 (Nrf2) is an important transcription factor which plays a pivotal role in detoxifying reactive oxygen species (ROS) and has been more recently shown to regulate inflammatory and antiviral responses.
Li Zhang   +5 more
doaj   +1 more source

Genetic characteristics of HA gene of influenza A (H1N1) virus isolated from severe and fatal infection cases in Guizhou province in 2019

open access: yesZhongguo gonggong weisheng, 2023
ObjectiveTo analyze characteristics and specific molecular sites of hemagglutinin (HA) gene of influenza A (H1N1) virus isolated among severe and deadly infection cases in Guizhou province in 2019 for providing evidence to influenza prevention and ...
Lijuan REN   +4 more
doaj   +1 more source

Viral Dynamics and Real-Time RT-PCR Ct Values Correlation with Disease Severity in COVID-19

open access: yesDiagnostics, 2021
Real-time RT-PCR is considered the gold standard confirmatory test for coronavirus disease 2019 (COVID-19). However, many scientists disagree, and it is essential to understand that several factors and variables can cause a false-negative test.
A. Rabaan   +15 more
semanticscholar   +1 more source

Viral diseases of the rabbit

open access: yesVeterinary Clinics of North America: Exotic Animal Practice, 2005
Viral disease in the rabbit is encountered infrequently by the clinical practitioner; however, several viral diseases were reported to occur in this species. Viral diseases that are described in the rabbit primarily may affect the integument, gastrointestinal tract or, central nervous system or maybe multi-systemic in nature.
Aric Krogstad   +2 more
openaire   +3 more sources

Complete genome analysis of hepatitis B virus in Qinghai-Tibet plateau: the geographical distribution, genetic diversity, and co-existence of HBsAg and anti-HBs antibodies

open access: yesVirology Journal, 2020
Background The genetic variation and origin of Hepatitis B Virus (HBV) in Qinghai-Tibet Plateau were poorly studied. The coexistence of HBsAg and anti-HBs has been described as a puzzle and has never been reported in the indigenous population or in ...
He Liu   +9 more
doaj   +1 more source

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load on Risk of Intubation and Mortality Among Hospitalized Patients With Coronavirus Disease 2019

open access: yesClinical Infectious Diseases, 2020
Background Patients hospitalized with coronavirus disease 2019 (COVID-19) frequently require mechanical ventilation and have high mortality rates. However, the impact of viral burden on these outcomes is unknown.
Reed Magleby   +8 more
semanticscholar   +1 more source

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