Results 51 to 60 of about 11,623,584 (386)

The relationship between COVID‐19 viral load and disease severity: A systematic review

Immunity, Inflammation and Disease, 2021
Patients with COVID‐19 may present different viral loads levels. However, the relationship between viral load and disease severity in COVID‐19 is still unknown. Therefore, this study aimed to systematically review the association between SARS‐CoV‐2 viral
Omid Dadras, A. Afsahi, Z. Pashaei, Hengameh Mojdeganlou, A. Karimi, Pedram Habibi, A. Barzegary, Amirata Fakhfouri, P. Mirzapour, Nazanin Janfaza, Soheil Dehghani, Fatemeh Afroughi, M. Dashti, S. Khodaei, E. Mehraeen, F. Voltarelli, J. Sabatier, Seyedahmad Seyedalinaghi   +17 more
semanticscholar   +1 more source

Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study. [PDF]

, 2016
BackgroundThe capacity of electronic health record (EHR) data to guide targeted surveillance in chronic kidney disease (CKD) is unclear. We sought to leverage EHR data for predicting risk of progressing from CKD to end-stage renal disease (ESRD) to help ...
Chertow, Glenn M, Hall, Yoshio N, Himmelfarb, Jonathan, Maziarz, Marlena, Tuot, Delphine S, Xie, Yuxiang   +5 more
core   +2 more sources

Impact of Severe Acute Respiratory Syndrome Coronavirus 2 Viral Load on Risk of Intubation and Mortality Among Hospitalized Patients With Coronavirus Disease 2019

Clinical Infectious Diseases, 2020
Background Patients hospitalized with coronavirus disease 2019 (COVID-19) frequently require mechanical ventilation and have high mortality rates. However, the impact of viral burden on these outcomes is unknown.
Reed Magleby, L. Westblade, Alex Trzebucki, M. Simon, M. Rajan, Joel C Park, P. Goyal, M. Safford, M. Satlin   +8 more
semanticscholar   +1 more source

Applicability of duplex real time and lateral flow strip reverse-transcription recombinase aided amplification assays for the detection of Enterovirus 71 and Coxsackievirus A16

Virology Journal, 2019
Background Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the two main etiological agents of Hand, Foot and Mouth Disease (HFMD). Simple and rapid detection of EV71 and CA16 is critical in resource-limited settings.
Xin-na Li, Xin-xin Shen, Ming-hui Li, Ju-ju Qi, Rui-huan Wang, Qing-xia Duan, Rui-qing Zhang, Tao Fan, Xue-ding Bai, Guo-hao Fan, Yao Xie, Xue-jun Ma   +11 more
doaj   +1 more source

Digestive Symptoms in COVID-19 Patients With Mild Disease Severity: Clinical Presentation, Stool Viral RNA Testing, and Outcomes

American Journal of Gastroenterology, 2020
OBJECTIVES: Coronavirus disease 2019 (COVID-19) most commonly presents with respiratory symptoms, including cough, shortness of breath, and sore throat.
Chaoqun Han, Caihan Duan, Shengyan Zhang, B. Spiegel, Huiying Shi, Weijun Wang, Lei Zhang, Rong Lin, Jun Liu, Zhen Ding, X. Hou   +10 more
semanticscholar   +1 more source

Association between upper respiratory tract viral load, comorbidities, disease severity and outcome of patients with SARS-CoV-2 infection

Journal of Infectious Diseases, 2021
Background There is limited information on the association between upper respiratory tract (URT) viral loads, host factors, and disease severity in SARS-CoV-2 infected patients. Methods We studied 1,122 patients (mean age: 46 years) diagnosed by PCR. URT
H. Maltezou, V. Raftopoulos, R. Vorou, K. Papadima, K. Mellou, N. Spanakis, A. Kossyvakis, G. Gioula, M. Exindari, Elisavet Froukala, B. Martinez-Gonzalez, G. Panayiotakopoulos, A. Papa, A. Mentis, A. Tsakris   +14 more
semanticscholar   +1 more source

Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons. [PDF]

, 2017
Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and ...
Boback, Scott M, DeRisi, Joseph L, Drazenovich, Tracy, Garcia, Valentina E, Hawkins, Michelle G, Hoon-Hanks, Laura L, Keel, M Kevin, Layton, Marylee L, Sanchez-Migallon Guzman, David, Stenglein, Mark D   +9 more
core   +1 more source

High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer

Journal of Extracellular Vesicles, 2019
Biological nanoparticles, including viruses and extracellular vesicles (EVs), are of interest to many fields of medicine as biomarkers and mediators of or treatments for disease.
A. Morales-Kastresana, Thomas Musich, J. Welsh, W. Telford, T. Demberg, James C S Wood, M. Bigos, Carley D Ross, Aliaksander Kachynski, Alan Dean, E. J. Felton, Jonathan E. Van Dyke, J. Tigges, Vasilis Toxavidis, D. Parks, W. R. Overton, A. Kesarwala, G. Freeman, Ariel Rosner, S. Perfetto, L. Pasquet, M. Terabe, K. McKinnon, V. Kapoor, J. Trepel, A. Puri, Hisataka Kobayashi, Bryant C Yung, Xiaoyuan Chen, P. Guion, P. Choyke, S. Knox, I. Ghiran, M. Robert-Guroff, J. Berzofsky, Jennifer C. Jones   +35 more
semanticscholar   +1 more source

Potential Application of the CRISPR/Cas9 System against Herpesvirus Infections. [PDF]

, 2018
The CRISPR/Cas9 system has been applied in the genome editing and disruption of latent infections for herpesviruses such as the herpes simplex virus, Epstein⁻Barr virus, cytomegalovirus, and Kaposi's sarcoma-associated herpesvirus.
Chen, Yuan-Chuan, Liu, Fenyong, Sheng, Jingxue, Trang, Phong   +3 more
core   +2 more sources

A host-protein signature is superior to other biomarkers for differentiating between bacterial and viral disease in patients with respiratory infection and fever without source: a prospective observational study

European Journal of Clinical Microbiology and Infectious Diseases, 2018
Bacterial and viral infections often present with similar symptoms. Etiologic misdiagnosis can alter the trajectory of patient care, including antibiotic overuse. A host-protein signature comprising tumor necrosis factor-related apoptosis-inducing ligand
L. Ashkenazi-Hoffnung, K. Oved, R. Navon, T. Friedman, O. Boíco, M. Paz, Gali Kronenfeld, L. Etshtein, Asi Cohen, T. Gottlieb, E. Eden, I. Chistyakov, I. Srugo, A. Klein, S. Ashkenazi, O. Scheuerman   +15 more
semanticscholar   +1 more source