Results 61 to 70 of about 10,975,124 (324)

The relationship between COVID‐19 viral load and disease severity: A systematic review

Immunity, Inflammation and Disease, 2021
Patients with COVID‐19 may present different viral loads levels. However, the relationship between viral load and disease severity in COVID‐19 is still unknown. Therefore, this study aimed to systematically review the association between SARS‐CoV‐2 viral
O. Dadras, A. Afsahi, Z. Pashaei, Hengameh Mojdeganlou, A. Karimi, Pedram Habibi, A. Barzegary, Amirata Fakhfouri, P. Mirzapour, Nazanin Janfaza, Soheil Dehghani, Fatemeh Afroughi, Mohsen Dashti, S. Khodaei, E. Mehraeen, F. Voltarelli, J. Sabatier, Seyedahmad Seyedalinaghi   +17 more
semanticscholar   +1 more source

FTY720 (fingolimod) modulates the severity of viral-induced encephalomyelitis and demyelination. [PDF]

, 2014
BackgroundFTY720 (fingolimod) is the first oral drug approved by the Food and Drug Administration for treatment of patients with the relapsing-remitting form of the human demyelinating disease multiple sclerosis.
Blanc, Caroline A, Lane, Thomas E, Rosen, Hugh   +2 more
core   +1 more source

Applicability of duplex real time and lateral flow strip reverse-transcription recombinase aided amplification assays for the detection of Enterovirus 71 and Coxsackievirus A16

Virology Journal, 2019
Background Enterovirus 71 (EV71) and coxsackievirus A16 (CA16) are the two main etiological agents of Hand, Foot and Mouth Disease (HFMD). Simple and rapid detection of EV71 and CA16 is critical in resource-limited settings.
Xin-na Li, Xin-xin Shen, Ming-hui Li, Ju-ju Qi, Rui-huan Wang, Qing-xia Duan, Rui-qing Zhang, Tao Fan, Xue-ding Bai, Guo-hao Fan, Yao Xie, Xue-jun Ma   +11 more
doaj   +1 more source

Restriction-Assembly: A Solution to Construct Novel Adenovirus Vector

Viruses, 2022
Gene therapy and vaccine development need more novel adenovirus vectors. Here, we attempt to provide strategies to construct adenovirus vectors based on restriction-assembly for researchers with little experience in this field.
Xiaojuan Guo, Yangyang Sun, Juan Chen, Xiaohui Zou, Wenzhe Hou, Wenjie Tan, Tao Hung, Zhuozhuang Lu   +7 more
doaj   +1 more source

High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer

Journal of Extracellular Vesicles, 2019
Biological nanoparticles, including viruses and extracellular vesicles (EVs), are of interest to many fields of medicine as biomarkers and mediators of or treatments for disease.
A. Morales-Kastresana, Thomas Musich, J. Welsh, W. Telford, T. Demberg, James C S Wood, M. Bigos, Carley D Ross, Aliaksander Kachynski, Alan Dean, E. J. Felton, Jonathan E. Van Dyke, J. Tigges, Vasilis Toxavidis, D. Parks, W. R. Overton, A. Kesarwala, G. Freeman, Ariel Rosner, S. Perfetto, L. Pasquet, M. Terabe, K. McKinnon, V. Kapoor, J. Trepel, A. Puri, Hisataka Kobayashi, Bryant C Yung, Xiaoyuan Chen, P. Guion, P. Choyke, S. Knox, I. Ghiran, M. Robert-Guroff, J. Berzofsky, Jennifer C. Jones   +35 more
semanticscholar   +1 more source

Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019

JAMA Network Open, 2020
Key Points Question What are the incidence rates of gastrointestinal symptoms among patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection?
S. Parasa, M. Desai, V. Thoguluva Chandrasekar, H. Patel, K. Kennedy, T. Roesch, M. Spadaccini, M. Colombo, R. Gabbiadini, E. Artifon, A. Repici, Prateek Sharma   +11 more
semanticscholar   +1 more source

Association between upper respiratory tract viral load, comorbidities, disease severity and outcome of patients with SARS-CoV-2 infection

Journal of Infectious Diseases, 2021
Background There is limited information on the association between upper respiratory tract (URT) viral loads, host factors, and disease severity in SARS-CoV-2 infected patients. Methods We studied 1,122 patients (mean age: 46 years) diagnosed by PCR. URT
H. Maltezou, V. Raftopoulos, R. Vorou, K. Papadima, K. Mellou, N. Spanakis, A. Kossyvakis, G. Gioula, M. Exindari, Elisavet Froukala, B. Martinez-Gonzalez, G. Panayiotakopoulos, A. Papa, A. Mentis, A. Tsakris   +14 more
semanticscholar   +1 more source

Viral Diseases

, 2012
The major focus of this chapter is the naturally occurring viral diseases of rabbits and hares. The viral diseases of rabbits are discussed in an order based on the taxonomic groups to which the viruses belong and are independent of the order of importance of the various diseases.
Ronald F Di Giacomo, Thea Brabb
openaire   +5 more sources

Tissue Tropism in Host Transcriptional Response to Members of the Bovine Respiratory Disease Complex. [PDF]

, 2017
Bovine respiratory disease (BRD) is the most common infectious disease of beef and dairy cattle and is characterized by a complex infectious etiology that includes a variety of viral and bacterial pathogens.
Behura, Susanta K, Gershwin, Laurel J, Grupioni, Natalia V, Kim, JaeWoo, Neibergs, Holly L, Regitano, Luciana CA, Schnabel, Robert D, Seabury, Christopher M, Taylor, Jeremy F, Tizioto, Polyana C, Toaff-Rosenstein, Rachel, Van Eenennaam, Alison L   +11 more
core   +3 more sources

A host-protein signature is superior to other biomarkers for differentiating between bacterial and viral disease in patients with respiratory infection and fever without source: a prospective observational study

European Journal of Clinical Microbiology and Infectious Diseases, 2018
Bacterial and viral infections often present with similar symptoms. Etiologic misdiagnosis can alter the trajectory of patient care, including antibiotic overuse. A host-protein signature comprising tumor necrosis factor-related apoptosis-inducing ligand
L. Ashkenazi-Hoffnung, K. Oved, R. Navon, T. Friedman, O. Boíco, M. Paz, Gali Kronenfeld, L. Etshtein, Asi Cohen, T. Gottlieb, E. Eden, I. Chistyakov, I. Srugo, A. Klein, S. Ashkenazi, O. Scheuerman   +15 more
semanticscholar   +1 more source