Results 61 to 70 of about 447,313 (350)

Exploring viral diversity in fermented vegetables through viral metagenomics

Food Microbiology
Fermented vegetables are traditionally produced using the endogenous microorganisms present in raw ingredients. While the diversity of bacteria and fungi in fermented vegetables has been relatively well studied, phage communities remain largely unexplored.
Cantuti Gendre, Julia, Le Marrec, Claire, Chaillou, Stéphane, Omhover-Fougy, Lysiane, Landaud, Sophie, Dugat-Bony, Eric   +5 more
openaire   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

A marine viral halogenase that iodinates diverse substrates [PDF]

Nature Chemistry, 2019
Oceanic cyanobacteria are the most abundant oxygen-generating phototrophs on our planet and are therefore important to life. These organisms are infected by viruses called cyanophages, which have recently shown to encode metabolic genes that modulate host photosynthesis, phosphorus cycling and nucleotide metabolism.
Gkotsi, Danai S, Ludewig, Hannes, Sharma, Sunil V, Connolly, Jack A, Dhaliwal, Jagwinder, Wang, Yunpeng, Unsworth, William P, Taylor, Richard J K, McLachlan, Matthew M W, Shanahan, Stephen, Naismith, James H, Goss, Rebecca J M   +11 more
openaire   +6 more sources

Previously unknown evolutionary groups dominate the ssDNA gokushoviruses in oxic and anoxic waters of a coastal marine environment

Frontiers in Microbiology, 2015
Metagenomic studies have revealed that ssDNA phages from the family Microviridae subfamily Gokushovirinae are widespread in aquatic ecosystems. It is hypothesized that gokushoviruses occupy specialized niches, resulting in differences among genotypes ...
Jessica M. Labonté, Steven eHallam, Curtis A. Suttle   +2 more
doaj   +1 more source

Viral Metagenomic Analysis of the Fecal Samples in Domestic Dogs (Canis lupus familiaris)

Viruses, 2023
Canine diarrhea is a common intestinal illness that is usually caused by viruses, bacteria, and parasites, and canine diarrhea may induce morbidity and mortality of domestic dogs if treated improperly.
Hongyan Wang, Zongjie Li, Chuanfeng Li, Yanfeng Ma, Qing Sun, Hailong Zhang, Guangbin Niu, Jianchao Wei, Huochun Yao, Zhiyong Ma   +9 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

High-level of viral genomic diversity in cervical cancers: a Brazilian study on human papillomavirus type 16 [PDF]

, 2015
Invasive cervical cancer (ICC) is the third most frequent cancer among women worldwide and is associated with persistent infection by carcinogenic human papillomaviruses (HPVs).
Adhemar Longatto-Filho, Akagi, Antonsson, Aromseree, Beckman, Bernard, Bouvard, Bragg, Bravo, Bravo, Bruni, Burk, Byrne, Canadas, Chen, Chen, Chen, Cristina Mendes de Oliveira, Cubie, Dall, de Oliveira, de Sanjose, de Sanjose, de Villiers, De Vuyst, Dillner, DiLorenzo, Doorbar, Doorbar, Edgar, Flores, Freitas, Gheit, Ignacio G. Bravo, Jesus Paula Carvalho, José Eduardo Levi, José Humberto Tavares Guerreiro Fregnani, Kukimoto, Levi, Li, Li, Liu, Loeb, Maria Luiza Nogueira Dias Genta, Maricy Tacla, Munk, Murray, Nathália Caroline Santiago e Souza, Orav, Quint, Rebollo, Smith, Stamatakis, Sun, Thorvaldsdottir, Valmary-Degano, Vartanian, Walboomers, Wang, Wang, Watts, Wentzensen, Xu, Yuan   +63 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Atypical viral dynamics from transport through popular places

, 2016
The flux of visitors through popular places undoubtedly influences viral spreading -- from H1N1 and Zika viruses spreading through physical spaces such as airports, to rumors and ideas spreading though online spaces such as chatrooms and social media ...
Hui, Pak Ming, Johnson, Neil F., Manrique, Pedro D., Xu, Chen   +3 more
core   +1 more source