Results 51 to 60 of about 2,929,622 (336)

Raw Sewage Harbors Diverse Viral Populations [PDF]

open access: yesmBio, 2011
ABSTRACT At this time, about 3,000 different viruses are recognized, but metagenomic studies suggest that these viruses are a small fraction of the viruses that exist in nature. We have explored viral diversity by deep sequencing nucleic acids obtained from virion populations enriched from raw sewage.
Cantalupo, Paul G   +10 more
openaire   +5 more sources

Metagenomic analysis of viral diversity in Portuguese bats. [PDF]

open access: yesVet Res Commun
Abstract Bats are highly diverse mammals and known reservoirs of numerous zoonotic viruses. Their role in the ecology of emerging infectious diseases continues to be of significant interest. This study aimed to evaluate the occurrence of coronaviruses (CoVs) in Portuguese bats and predict the affinity of their ...
Hemnani M   +8 more
europepmc   +6 more sources

Estimating T-cell repertoire diversity: limitations of classical estimators and a new approach [PDF]

open access: yes, 2015
A highly diverse T-cell receptor (TCR) repertoire is a fundamental property of an effective immune system, and is associated with efficient control of viral infections and other pathogens. However, direct measurement of total TCR diversity is impossible.
Asquith, RE, Bangham, C, Laydon, D
core   +1 more source

Norovirus Epidemiology and Genetic Diversity in Leipzig, Germany during 2013–2017

open access: yesViruses, 2021
Globally and in all age groups, noroviruses are a main cause of gastroenteritis. To assess their local epidemiology and genetic diversity, stool samples of 7509 inpatients with gastrointestinal complaints from all age groups were analyzed.
Nora Ennuschat   +3 more
doaj   +1 more source

High Transcriptional Activity and Diverse Functional Repertoires of Hundreds of Giant Viruses in a Coastal Marine System

open access: yesmSystems, 2021
Viruses belonging to the Nucleocytoviricota phylum are globally distributed and include members with notably large genomes and complex functional repertoires.
Anh D. Ha   +2 more
doaj   +1 more source

Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]

open access: yes, 2015
Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric   +14 more
core   +2 more sources

Viromes of Coastal Waters of the North Caspian Sea: Initial Assessment of Diversity and Functional Potential

open access: yesDiversity, 2023
In recent years, the study of marine viromes has become one of the most relevant areas of geoecology. Viruses are the most numerous, genetically diverse and pervasive biological entities on Earth, including in aquatic ecosystems.
Madina S. Alexyuk   +5 more
doaj   +1 more source

Virus and host factors affecting the clinical outcome of bluetongue virus infection [PDF]

open access: yes, 2014
Bluetongue is a major infectious disease of ruminants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides. Here, we assessed virus and host factors influencing the clinical outcome of BTV infection using a single experimental ...
Caporale, Marco   +9 more
core   +3 more sources

Coping with Viral Diversity in HIV Vaccine Design [PDF]

open access: yesPLoS Computational Biology, 2007
The ability of human immunodeficiency virus type 1 (HIV-1) to develop high levels of genetic diversity, and thereby acquire mutations to escape immune pressures, contributes to the difficulties in producing a vaccine. Possibly no single HIV-1 sequence can induce sufficiently broad immunity to protect against a wide variety of infectious strains, or ...
David C. Nickle   +8 more
openaire   +5 more sources

Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic

open access: yesViruses, 2021
During the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution ...
Blanca Taboada   +22 more
doaj   +1 more source

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