Results 31 to 40 of about 2,646,395 (299)
Coping with Viral Diversity in HIV Vaccine Design [PDF]
PLoS Computational Biology, 2007 The ability of human immunodeficiency virus type 1 (HIV-1) to develop high levels of genetic diversity, and thereby acquire mutations to escape immune pressures, contributes to the difficulties in producing a vaccine. Possibly no single HIV-1 sequence can induce sufficiently broad immunity to protect against a wide variety of infectious strains, or ...
David C. Nickle +8 more
openaire +6 more sources
Frontiers in Microbiology, 2017 Human rhinovirus (HRV) remains a leading cause of several human diseases including the common cold. Despite considerable research over the last 60 years, development of an effective vaccine to HRV has been viewed by many as unfeasible due, in part, to ...
Christopher C. Stobart +3 more
doaj +1 more source
Biomolecules, 2022 Although traditionally viewed as streamlined and simple, discoveries over the last century have revealed that viruses can exhibit surprisingly complex physical structures, genomic organization, ecological interactions, and evolutionary histories. Viruses
Frank O. Aylward, Mohammad Moniruzzaman
doaj +1 more source
, 2022 Pineapple (Ananas comosus L. [Merr.]) accessions from the U.S. Tropical Plant Genetic Resources and Disease Research (TPGRDR) in Hilo, Hawaii were subjected to RNA-sequencing to study the occurrence of viral populations associated with this vegetatively ...
Ryan Domingo +19 more
core +1 more source
Norovirus Epidemiology and Genetic Diversity in Leipzig, Germany during 2013–2017
Viruses, 2021 Globally and in all age groups, noroviruses are a main cause of gastroenteritis. To assess their local epidemiology and genetic diversity, stool samples of 7509 inpatients with gastrointestinal complaints from all age groups were analyzed.
Nora Ennuschat +3 more
doaj +1 more source
mSystems, 2021 Viruses belonging to the Nucleocytoviricota phylum are globally distributed and include members with notably large genomes and complex functional repertoires.
Anh D. Ha +2 more
doaj +1 more source
Diversity, 2023 In recent years, the study of marine viromes has become one of the most relevant areas of geoecology. Viruses are the most numerous, genetically diverse and pervasive biological entities on Earth, including in aquatic ecosystems.
Madina S. Alexyuk +5 more
doaj +1 more source
Metagenomic analysis of viral diversity in Portuguese bats. [PDF]
Vet Res CommunAbstract Bats are highly diverse mammals and known reservoirs of numerous zoonotic viruses. Their role in the ecology of emerging infectious diseases continues to be of significant interest. This study aimed to evaluate the occurrence of coronaviruses (CoVs) in Portuguese bats and predict the affinity of their ...
Hemnani M +8 more
europepmc +7 more sources
RNA virome comparison between sylvatic and urban-interface mosquitoes from Southeastern Brazil
Frontiers in Cellular and Infection MicrobiologyIntroductionMosquitoes (Diptera: Culicidae) are primary vectors of public health pathogens, yet their core viromes remain poorly characterized, particularly in Neotropical sylvatic lineages.
Geovani de Oliveira Ribeiro +15 more
doaj +1 more source
Genetic Analysis of SARS-CoV-2 Variants in Mexico during the First Year of the COVID-19 Pandemic
Viruses, 2021 During the first year of the SARS-CoV-2 pandemic in Mexico, more than two million people were infected. In this study, we analyzed full genome sequences from 27 February 2020 to 28 February 2021 to characterize the geographical and temporal distribution ...
Blanca Taboada +22 more
doaj +1 more source