Results 41 to 50 of about 2,646,395 (299)

Evolutionary features of new picorna-like viruses in Culex (Melanoconion) mosquitoes

Current Research in Parasitology and Vector-Borne Diseases
In this study, we investigated unclassified picorna-like viruses in Culex (Melanoconion) mosquitoes from São Paulo, Brazil, an area of high mosquito biodiversity and arbovirus activity.
Lilian de Oliveira Guimarães, Ariel Rocha de Almeida, Endrya do Socorro Foro Ramos, Juliana Telles-de-Deus, Vanessa Christe Helfstein, Vanessa dos Santos Morais, Jesus Maia dos Santos, Ramendra Pati Pandey, Vera Lucia Fonseca de Camargo-Neves, Antonio Charlys da Costa, Karin Kirchgatter, Élcio Leal   +11 more
doaj   +1 more source

The Prevalence of Viral Pathogens among Bats in Kazakhstan

Viruses, 2022
Bats carry thousands of viruses from 28 different families. To determine the presence of various pathogens in bat populations in Kazakhstan, 1149 samples (393 oropharyngeal swabs, 349 brain samples, 407 guano) were collected.
Adilbay I. Karagulov, Takhmina U. Argimbayeva, Zamira D. Omarova, Ali B. Tulendibayev, Laura Zh. Dushayeva, Marina A. Svotina, Aibarys M. Melisbek, Nurdos A. Aubakir, Sabyrkhan M. Barmak, Kulyaisan T. Sultankulova, Dana A. Alibekova, Tanat T. Yermekbai, Askar M. Nametov, Dmitry A. Lozovoy, Khairulla B. Abeuov, Mukhit B. Orynbayev   +15 more
doaj   +1 more source

Duck gut viral metagenome analysis captures snapshot of viral diversity [PDF]

Gut Pathogens, 2016
Ducks (Anas platyrhynchos) an economically important waterfowl for meat, eggs and feathers; is also a natural reservoir for influenza A viruses. The emergence of novel viruses is attributed to the status of co-existence of multiple types and subtypes of viruses in the reservoir hosts.
Fawaz, Mohammed, Vijayakumar, Periyasamy, Mishra, Anamika, Gandhale, Pradeep N., Dutta, Rupam, Kamble, Nitin M., Sudhakar, Shashi B., Roychoudhary, Parimal, Kumar, Himanshu, Kulkarni, Diwakar D., Raut, Ashwin Ashok   +10 more
openaire   +2 more sources

Putative Novel Viruses in the Families Lispiviridae and Rhabdoviridae Detected in Culex and Anopheles Mosquitoes Collected at the São Paulo Zoo

Advances in Virology
Several viruses belonging to the order Mononegavirales are recognized as highly pathogenic in humans and are often associated with lethal disease outcomes.
Lilian de Oliveira Guimarães, Roseane da Silva Couto, Geovani de Oliveira Ribeiro, Juliana Telles-de-Deus, Endrya do Socorro Foro Ramos, Vanessa Christe Helfstein, Vanessa dos Santos Morais, Jesus Maia dos Santos, Ramendra Pati Pandey, Vera Lucia Fonseca de Camargo-Neves, Antonio Charlys da Costa, Karin Kirchgatter, Élcio Leal   +12 more
doaj   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Exploring the Genomics of Marnaviridae Family: Identification, Characterization, and Taxonomic Implications

International Journal of Microbiology
In this study, we characterized sequences similar to Marnaviridae obtained from water samples in the state of São Paulo, Brazil. Sixteen complete or nearly complete genomes were determined, all of them positive-sense single-stranded RNA, with lengths ...
Mikaela Renata Funada Barbosa, Endrya do Socorro Foro Ramos, Fabiola Villanova, Renan Lourenço Oliveira Silva, Suzi Cristina Garcia, Ronalda Silva de Araújo, Maria Cássia Mendes-Correa, Tania Regina Tozetto-Mendoza, Wen Zhang, Ramendra Pati Pandey, Adriana Luchs, Maria Inês Zanoli Sato, Antonio Charlys da Costa, Elcio Leal   +13 more
doaj   +1 more source

Abatacept for Prophylaxis of Acute and Chronic Graft‐Versus‐Host‐Disease in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation—A Systematic Review and Meta‐Analysis of Cohort Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Graft‐versus‐host disease (GvHD) remains one of the most significant complications of hematopoietic stem cell transplantation (HSCT). Abatacept, a selective T‐cell costimulation modulator, is a relatively novel prophylactic agent, though pediatric data remain limited.
Matthijs D. Kruizinga, Anne B. Verbeek, Caroline A. Lindemans, Emilie P. Buddingh   +3 more
wiley   +1 more source

The Role of the Flavivirus Replicase in Viral Diversity and Adaptation

Viruses, 2022
Flaviviruses include several emerging and re-emerging arboviruses which cause millions of infections each year. Although relatively well-studied, much remains unknown regarding the mechanisms and means by which these viruses readily alternate and adapt to different hosts and environments.
Haley S. Caldwell, Janice D. Pata, Alexander T. Ciota   +2 more
openaire   +3 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Diverse viral proteases activate the NLRP1 inflammasome [PDF]

eLife, 2020
The NLRP1 inflammasome is a multiprotein complex that is a potent activator of inflammation. Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, resulting in degradation of the N-terminal domains of NLRP1B and liberation of the bioactive C-terminal domain, which includes the caspase activation and ...
Brian V Tsu, Christopher Beierschmitt, Andrew P Ryan, Rimjhim Agarwal, Patrick S Mitchell, Matthew D Daugherty   +5 more
openaire   +4 more sources