Results 41 to 50 of about 2,929,622 (336)
High Heritability Is Compatible with the Broad Distribution of Set Point Viral Load in HIV Carriers. [PDF]
Set point viral load in HIV patients ranges over several orders of magnitude and is a key determinant of disease progression in HIV. A number of recent studies have reported high heritability of set point viral load implying that viral genetic factors ...
Bonhoeffer, S, Fraser, C, Leventhal, GE
core +3 more sources
High error rates of viral RNA-dependent RNA polymerases lead to diverse intra-host viral populations during infection. Errors made during replication that are not strongly deleterious to the virus can lead to the generation of minority variants. However,
A. Roder +20 more
semanticscholar +1 more source
Genetic diversity in the env V1-V2 region of proviral quasispecies from long-term controller MHC-typed cynomolgus macaques infected with SHIVSF162P4cy [PDF]
Intra-host evolution of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) has been shown by viral RNA analysis in subjects who naturally suppress plasma viremia to low levels, known as controllers.
Borsetti, Alessandra +11 more
core +1 more source
Viral sensors: diversity in pathogen recognition [PDF]
Summary: Innate sensors of viral infection detect viral products and initiate the signal cascades that lead to the antiviral response. Several proteins have been identified to play a role in this process, mostly members of the Toll‐like receptor and retinoic acid‐inducible gene I‐like receptor families.
Stephen A, McCartney, Marco, Colonna
openaire +2 more sources
Assessing the Diversity of Endogenous Viruses Throughout Ant Genomes
Endogenous viral elements (EVEs) can play a significant role in the evolution of their hosts and have been identified in animals, plants, and fungi.
Peter J. Flynn +3 more
doaj +1 more source
Microbial and metabolic succession on common building materials under high humidity conditions. [PDF]
Despite considerable efforts to characterize the microbial ecology of the built environment, the metabolic mechanisms underpinning microbial colonization and successional dynamics remain unclear, particularly at high moisture conditions. Here, we applied
Cardona, Cesar +12 more
core +3 more sources
Although traditionally viewed as streamlined and simple, discoveries over the last century have revealed that viruses can exhibit surprisingly complex physical structures, genomic organization, ecological interactions, and evolutionary histories. Viruses
Frank O. Aylward, Mohammad Moniruzzaman
doaj +1 more source
A marine viral halogenase that iodinates diverse substrates [PDF]
Oceanic cyanobacteria are the most abundant oxygen-generating phototrophs on our planet and are therefore important to life. These organisms are infected by viruses called cyanophages, which have recently shown to encode metabolic genes that modulate host photosynthesis, phosphorus cycling and nucleotide metabolism.
Gkotsi, Danai S +11 more
openaire +7 more sources
Human rhinovirus (HRV) remains a leading cause of several human diseases including the common cold. Despite considerable research over the last 60 years, development of an effective vaccine to HRV has been viewed by many as unfeasible due, in part, to ...
Christopher C. Stobart +3 more
doaj +1 more source
Shared and Distinct Features of Human Milk and Infant Stool Viromes. [PDF]
Infants acquire many of their microbes from their mothers during the birth process. The acquisition of these microbes is believed to be critical in the development of the infant immune system.
Abdul A. Saboory +9 more
core +2 more sources

