Results 71 to 80 of about 2,929,622 (336)

Virome of Rhipicephalus ticks by metagenomic analysis in Guangdong, southern China

Frontiers in Microbiology, 2022
Tick-borne viruses (TBVs) have increasingly caused a global public health concern. This study collected Rhipicephalus ticks in Guangdong, southern China to identify RNA viruses.
Luanying Guo, Jun Ma, Junwei Lin, Meiyi Chen, Wei Liu, Jin Zha, Qinqin Jin, Hongrong Hong, Weinan Huang, Li Zhang, Ketong Zhang, Zhengkai Wei, Quan Liu, Quan Liu   +13 more
doaj   +1 more source

Reproducibly sampling SARS-CoV-2 genomes across time, geography, and viral diversity.

F1000Research, 2020
The COVID-19 pandemic has led to a rapid accumulation of SARS-CoV-2 genomes, enabling genomic epidemiology on local and global scales. Collections of genomes from resources such as GISAID must be subsampled to enable computationally feasible phylogenetic
Evan Bolyen, Matthew R. Dillon, N. Bokulich, J. Ladner, B. Larsen, Crystal M. Hepp, D. Lemmer, J. Sahl, Andrew Sanchez, C. Holdgraf, C. Sewell, Aakash G Choudhury, J. Stachurski, M. Mckay, D. Engelthaler, M. Worobey, P. Keim, P. Keim, J. Caporaso   +18 more
semanticscholar   +1 more source

Strength in Diversity: Nuclear Export of Viral RNAs [PDF]

Viruses, 2020
The nuclear export of cellular mRNAs is a complex process that requires the orchestrated participation of many proteins that are recruited during the early steps of mRNA synthesis and processing. This strategy allows the cell to guarantee the conformity of the messengers accessing the cytoplasm and the translation machinery.
Jón Pol Gales, Julie Kubina, Angèle Geldreich, Maria Dimitrova   +3 more
openaire   +4 more sources

Exploring the Genomics of Marnaviridae Family: Identification, Characterization, and Taxonomic Implications

International Journal of Microbiology
In this study, we characterized sequences similar to Marnaviridae obtained from water samples in the state of São Paulo, Brazil. Sixteen complete or nearly complete genomes were determined, all of them positive-sense single-stranded RNA, with lengths ...
Mikaela Renata Funada Barbosa, Endrya do Socorro Foro Ramos, Fabiola Villanova, Renan Lourenço Oliveira Silva, Suzi Cristina Garcia, Ronalda Silva de Araújo, Maria Cássia Mendes-Correa, Tania Regina Tozetto-Mendoza, Wen Zhang, Ramendra Pati Pandey, Adriana Luchs, Maria Inês Zanoli Sato, Antonio Charlys da Costa, Elcio Leal   +13 more
doaj   +1 more source

Global estimates of mammalian viral diversity accounting for host sharing

Nature Ecology & Evolution, 2019
Present estimates suggest there are over 1 million virus species found in mammals alone, with about half a million posing a possible threat to human health.
C. Carlson, C. Zipfel, R. Garnier, S. Bansal   +3 more
semanticscholar   +1 more source

Characterization of SARS-CoV-2 viral diversity within and across hosts

bioRxiv, 2020
In light of the current COVID-19 pandemic, there is an urgent need to accurately infer the evolutionary and transmission history of the virus to inform real-time outbreak management, public health policies and mitigation strategies.
P. Sashittal, Yunan Luo, Jian Peng, M. El-kebir   +3 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Role of the Flavivirus Replicase in Viral Diversity and Adaptation

Viruses, 2022
Flaviviruses include several emerging and re-emerging arboviruses which cause millions of infections each year. Although relatively well-studied, much remains unknown regarding the mechanisms and means by which these viruses readily alternate and adapt to different hosts and environments.
Haley S. Caldwell, Janice D. Pata, Alexander T. Ciota   +2 more
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Metagenomic-based Surveillance of Pacific Coast tick Dermacentor occidentalis Identifies Two Novel Bunyaviruses and an Emerging Human Ricksettsial Pathogen. [PDF]

, 2017
An increasing number of emerging tick-borne diseases has been reported in the United States since the 1970s. Using metagenomic next generation sequencing, we detected nucleic acid sequences from 2 novel viruses in the family Bunyaviridae and an emerging ...
Bouquet, Jerome, Chiu, Charles Y, Delwart, Eric, Lane, Robert S, Melgar, Michael, Swei, Andrea   +5 more
core   +2 more sources