A Genomic Surveillance Circuit for Emerging Viral Pathogens
Genomic surveillance has been crucial in monitoring the evolution and spread of SARS-CoV-2. In Andalusia (Spain), a coordinated genomic surveillance circuit was established to systematically sequence and analyze viral genomes across the region. This initiative organizes sample collection through 27 hospitals, which act as regional hubs within their ...
Carlos S, Casimiro-Soriguer +16 more
openaire +5 more sources
Ten years of surveillance for invasive Streptococcus pneumoniae during the era of antiretroviral scale-up and cotrimoxazole prophylaxis in Malawi. [PDF]
OBJECTIVE: To document trends in invasive pneumococcal disease (IPD) in a central hospital in Malawi during the period of national scale-up of antiretroviral therapy (ART) and cotrimoxazole prophylaxis.
Mavuto Mukaka +41 more
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A One Health cross-sectoral surveillance approach was implemented to screen biological samples from bats, pigs, and humans at high-risk interfaces for zoonotic viral spillover for five viral families with zoonotic potential in Viet Nam.
Alice Latinne +22 more
doaj +1 more source
Recombination in enteroviruses is a biphasic replicative process involving the generation of greater-than genome length 'imprecise' intermediates [PDF]
Recombination in enteroviruses provides an evolutionary mechanism for acquiring extensive regions of novel sequence, is suggested to have a role in genotype diversity and is known to have been key to the emergence of novel neuropathogenic variants of ...
David J Evans +13 more
core +1 more source
Nationwide wastewater sequencing surveillance of SARS-CoV-2 lineages: validation against clinical data across 28 U.S. states [PDF]
As clinical SARS-CoV-2 surveillance programs are being reduced, wastewater-based epidemiology (WBE) has emerged as a promising alternative for monitoring viral circulation.
Alessandro Zulli +6 more
doaj +2 more sources
Developing framework toward one health approach: Relevance and future implications
Against a constant background of recognized infections, epidemics of new and old infectious diseases periodically emerge, greatly magnifying the global burden of emerging and re-emerging diseases.
Suraj Kapoor
doaj +1 more source
Wastewater surveillance has been a tool for public health officials throughout the COVID-19 pandemic. Universities established pandemic response committees to facilitate safe learning for students, faculty, and staff. These committees met to analyze both
Alexis M. Porter +3 more
doaj +1 more source
Genomic diversity of SARS-CoV-2 in Oxford during United Kingdom’s first national lockdown
Epidemiological efforts to model the spread of SARS-CoV-2, the virus that causes COVID-19, are crucial to understanding and containing current and future outbreaks and to inform public health responses.
Altar M. Munis +4 more
doaj +1 more source
Recombination in Positive-Strand RNA Viruses
RNA recombination is a major driver of genetic shifts tightly linked to the evolution of RNA viruses. Genomic recombination contributes substantially to the emergence of new viral lineages, expansion in host tropism, adaptations to new environments, and ...
Haiwei Wang +3 more
doaj +1 more source
Spillover and emergence of bat-origin viral infections [PDF]
This thesis describes four years of research to quantify and characterise the system dynamics of bat-origin viral emergence events. Chapters 2–5 are comprised of four quantitative analyses: a compartmental model comparison of stochastic henipavirus ...
core +2 more sources

